Arithmetic of subthreshold synaptic summation in a model CA1 pyramidal cell. Porazi P, Brannon T, Mel BW (2003a) Neuron 37:977-987
Pyramidal Neuron as Two-Layer Neural Network. Porazi P, Brannon T, Mel BW (2003b) Neuron 37:989-999
This model was originally developed in NEURON
More details on the original NEURON version of this model here
In addition we created a simplified NEURON version, with a single cell and current clamp (in order to create a .mep file, which against LEMS/NeuroML2 implementation could be tested). More detailes on this NEURON version here
This model will be converted to NeuroML2/LEMS ... see more here
Issues:
- T-type Ca++ channel (see more here)
- the setup of the NEURON model uses a custom distance measurement (perpendicular distance), which is not reproducable in NeuroML2 -> we suggest to keep the morphology and the channels, but reoptimise the model