Specs code implements several heuristic methods for detection of conserved regions on protein sequence and structure. The purpose of such an exercise is, typically, to help in the rational design of single-site mutational experiments, to estimate the impact of SNPs - inherited or arising in cancerous cells, or to guide computational docking.

To see the code at work on precompiled vertebrate sequences check out CubeDB server. To try it on your own set of seqeunces you can visit Cube server. To compile an run locally, read on.

See the original README file.