/**
* Calculates the length of a string considering formatting stuff like \033[31m.
* @param str The string.
* @return The amount of character (=length).
*/
int GameManager::getLength(std::string str)
{
// Length of 6:
// UNDERLINE : \033[4m
// BOLD : \033[1m
// NOTHING : \033[0m
// Length of 7:
// ROT : \033[31m
// DARK GREEN : \033[32m
// BROWN : \033[33m
// BLUE : \033[34m
// LIGHT GREEN: \033[36m
// GRAY : \033[37m
int amount6 = 0;
int amount7 = 0;
amount6 += countSubstring(str, "\033[0m");
amount6 += countSubstring(str, "\033[1m");
amount6 += countSubstring(str, "\033[4m");
amount7 += countSubstring(str, "\033[31m");
amount7 += countSubstring(str, "\033[32m");
amount7 += countSubstring(str, "\033[33m");
amount7 += countSubstring(str, "\033[34m");
amount7 += countSubstring(str, "\033[36m");
amount7 += countSubstring(str, "\033[37m");
return str.length() - amount6 * 6 - amount7 * 7 + 1;
}
// ===================================================
// Set Methods
// ===================================================
void
Parser::setString ( const std::string& string, const std::string& stringSeparator )
{
#ifdef HAVE_LIFEV_DEBUG
debugStream ( 5030 ) << "Parser::setString strings: " << string << "\n";
#endif
M_strings.clear();
boost::split ( M_strings, string, boost::is_any_of ( stringSeparator ) );
//Remove white space to speed up the parser
for ( UInt i = 0; i < M_strings.size(); ++i )
{
boost::replace_all ( M_strings[i], " ", "" );
}
//Reserve the space for results
M_results.clear();
M_results.reserve ( countSubstring ( "," ) + 1 );
M_evaluate = true;
}
//M+
void mp(
int MinCoreSize,
int MaxCoreSize,
int SamplingFreq,
int NumReplicates,
char* OutFilePath,
std::string Kernel,
vector<int> KernelAccessionIndex,
vector<int> AccessionNameList,
vector<vector<vector<int> > > ActiveAlleleByPopList,
vector<vector<vector<int> > > TargetAlleleByPopList,
vector<int> ActiveMaxAllelesList,
vector<int> TargetMaxAllelesList,
vector<std::string> FullAccessionNameList
)
{
//PERFORM INITIAL MPI STUFF
MPI_Status status; //this struct contains three fields which will contain info about the sender of a received message
// MPI_SOURCE, MPI_TAG, MPI_ERROR
//MPI::Init (); //Initialize MPI.
int nproc = MPI::COMM_WORLD.Get_size ( ); //Get the number of processes.
int procid = MPI::COMM_WORLD.Get_rank ( ); //Get the individual process ID.
//set up vectors to fill with results
//below is a stupid way to calculate the number of rows in the output file, value l (which = V1)
//used to monitor progress and as the maximum vector index for shared output vectors
int l=0;
for (int i=MinCoreSize;i<MaxCoreSize+1;i=i+SamplingFreq)
{
for (int j=0;j<NumReplicates;j++)
{
l++;
}
}
double V1 = (double)l; //(MaxCoreSize - MinCoreSize + 1)*NumReplicates; //number of rows in output vectors
vector<vector<double> > Results(V1, vector<double>(9)); //will contain numerical results
vector<vector<string> > Members(V1); //will contain core set members
//***MPI: RECEIVE RESULTS AT MASTER 0
//receive values from any slave, in any order, exiting when the number of 'receives' = the top vector size
if ( procid == 0 )
{
//set up variables for monitoring progress
int percent; //percent of analysis completed
int progindex = 0; //index to monitor progress, percent = 100*(progindex/l)
//receive and process results from slave processors
unsigned int i = 0;
while (i<2*(Results.size())) //two receives per row
{
//probe the incoming message to determine its tag
int nchar; //will contain the length of the char array passed with tag=1
int vchar; //will contain the length of the vector passed with tag=0
int tag; //tag of message from sender
int source; //procid of sender
MPI_Probe(MPI_ANY_SOURCE, MPI_ANY_TAG, MPI_COMM_WORLD, &status);
//MPI_Get_count(&status, MPI_CHAR, &nchar); //probes the length of the message, saves it in nchar
tag = status.MPI_TAG; //the tag defines which kind of comm it is, a vector of stats (0=resvec())
//or a char array describing the members of the core (1=cc)
source = status.MPI_SOURCE; //determine the source of the message so that you can define which sender to Recv from. This will avoid an intervening message coming in after the MPI_Probe with a different length, causing a message truncated error.
if (tag == 0)
{
//determine the length of the message tagged 0
MPI_Get_count(&status, MPI_DOUBLE, &vchar);
//cout <<" vchar="<<vchar<<" tag="<<tag<<" MPI_SOURCE="<<status.MPI_SOURCE<<" MPI_ERROR="<<status.MPI_ERROR<<"\n";
//receive the vector of results, tagged 0, from:
//MPI_Send(&resvec[0], resvec.size(), MPI_DOUBLE, 0, 0, MPI_COMM_WORLD);
vector<double> t(10);
MPI_Recv(&t[0], vchar, MPI_DOUBLE, source, 0, MPI_COMM_WORLD, &status);
//load data from vector received onto Results, row number is last item t[9]
for (int j=0;j<9;++j)
{
Results[ t[9] ][j] = t[j];
}
t.clear();
}
else if (tag == 1)
{
//determine the length of the message tagged 1
MPI_Get_count(&status, MPI_CHAR, &nchar); //probes the length of the message, saves it in nchar
//cout <<" nchar="<<nchar<<" tag="<<tag<<" MPI_SOURCE="<<status.MPI_SOURCE<<" MPI_ERROR="<<status.MPI_ERROR<<"\n";
//receive the vector<string> of the core set, tagged 1, from:
//MPI_Send(&m[0], nchar, MPI_CHAR, 0, 1, MPI_COMM_WORLD);
//vector<string> m(nchar);
char m[nchar];
MPI_Recv(&m[0], nchar, MPI_CHAR, source, 1, MPI_COMM_WORLD, &status);
//load core set onto Members
//1. convert char array into a string
string mstr(m);
//2. split string on delimiter ',<!>,'
string delim = ",<!>,";
vector<string> mvec( countSubstring(mstr, delim) );
unsigned int st = 0;
std::size_t en = mstr.find(delim);
int k = 0;
while (en != std::string::npos)
{
mvec[k] = mstr.substr(st, en-st);
st = en + delim.length();
en = mstr.find(delim,st);
++k;
}
string z = mstr.substr(st); //get row number as last item in mstr
int zz = atoi(z.c_str()); //convert string to c-string then to int
//3. load onto Members
Members[zz] = mvec;
//4. clean up
memset(m, 0, nchar);; mstr=""; mvec.clear();
}
++i;
//display progress
progindex = progindex + 1;
percent = 100*( progindex/(V1*2) ); //number of rows X 2 repeats needed to complete search
printProgBar(percent);
}
}//***MPI: END MASTER RECEIVE***/
/***MPI: SEND RESULTS FROM SLAVE PROCESSES***/
else if ( procid != 0 )
{
unsigned int r; //r = core size,
//int nr, RandAcc, b, bsc, plateau; //nr = controller to repeat NumReplicates times
int RandAcc, b, bsc, plateau; //nr = controller to repeat NumReplicates times
//row = result vector row number, bsc = holds best sub core member, and other indexed accessions
//plateau = index of the number of reps in optimization loop with same diversity value
double RandomActiveDiversity;
double AltRandomActiveDiversity;
double StartingRandomActiveDiversity;
double StartingAltRandomActiveDiversity;
double RandomTargetDiversity;
double AltRandomTargetDiversity;
double StartingDiversity;
double TempAltOptimizedActiveDiversity;
double AltOptimizedActiveDiversity;
double OptimizedTargetDiversity;
double AltOptimizedTargetDiversity;
double best;
double nnew;
vector<vector<vector<int> > > AlleleList;
vector<vector<vector<int> > > CoreAlleles;
vector<vector<vector<int> > > TdTempList;
vector<vector<vector<int> > > BestSubCoreAlleles;
std::string Standardize = "yes"; //a run that mimics the MSTRAT approach can be accomplished by setting Standardize="no", and setting up the var file so that each column in the .dat file is treated as a single locus, rather than two (or more) adjacent columns being treated as a single codominant locus.
vector<int> AccessionsInCore;
vector<int> AccessionsInSubCore;
vector<int> BestSubCore;
vector<int> BestSubCoreRevSorted;
vector<int> TempList;
vector<int> TempList2;
vector<int> bestcore;
vector<std::string> TempListStr;
//seed the random number generator for each processor
int tt;
tt = (time(NULL));
srand ( abs(((tt*181)*((procid-83)*359))%104729) );
//do parallelization so that each rep by core size combo can be
//handled by a distinct thread. this involves figuring out the total
//number of reps*coresizes taking into account the SamplingFreq
int rsteps = 1 + floor( (MaxCoreSize - MinCoreSize) / SamplingFreq ); //number of steps from MinCoreSize to MaxCoreSize
//***MPI: figure out where to start and stop loop for each processor
int nreps = rsteps*NumReplicates;
int count = nreps/(nproc-1); //p-1 assumes a master, i.e. one less processor than total
int start = (procid-1) * count; //procid-1 makes you start at 0, assumes master is p0
int stop;
if (nreps % (nproc-1) > (procid-1))
{
start += procid - 1;
stop = start + (count + 1);
}
else
{
start += nreps % (nproc-1);
stop = start + count;
}
//iterate thru the relevant rows
for (int rnr=start;rnr<stop;++rnr)
{
r = MinCoreSize + ((rnr / NumReplicates) * SamplingFreq); //int rounds to floor
//develop random starting core set
//clear AccessionsInCore and set size
AccessionsInCore.clear();
AccessionsInCore.resize(r);
//add kernel accessions to core, if necessary
if (Kernel == "yes")
{
for (unsigned int i=0;i<KernelAccessionIndex.size();i++)
{
AccessionsInCore[i] = KernelAccessionIndex[i];
}
}
//clear TempList and set size
TempList.clear();
TempList.resize( AccessionNameList.size() );
//set list of available accessions in TempList, by erasing those already in the core
TempList = AccessionNameList;
//expunge the kernel accessions, so they are not available for random addition below
//KernelAccessionIndex has been reverse sorted so you don't go outside range after automatic resize by .erase
for (unsigned int i=0;i<KernelAccessionIndex.size();i++)
{
b = KernelAccessionIndex[i];
TempList.erase(TempList.begin()+b);
}
//randomly add accessions until r accessions are in the core. if there is a kernel, include those (done above)
//plus additional, randomly selected accessions, until you get r accessions
for (unsigned int i=KernelAccessionIndex.size();i<r;i++)
{
//choose an accession randomly from those available
RandAcc = rand() % TempList.size();
//add it to the list
AccessionsInCore[i] = TempList[RandAcc];
//remove it from the list of available accessions
TempList.erase(TempList.begin()+RandAcc);
}
//assemble genotypes for random core and calculate diversity
//1. put together initial list of active alleles
CoreAlleles.clear();
CoreAlleles.resize( AccessionsInCore.size() );
for (unsigned int i=0;i<AccessionsInCore.size();i++)
{
b = AccessionsInCore[i];
CoreAlleles[i] = ActiveAlleleByPopList[b];
}
//2. calculate diversity from random selection at active loci
AlleleList.clear();
AlleleList = CoreAlleles;
MyCalculateDiversity(AlleleList, ActiveMaxAllelesList, Standardize, RandomActiveDiversity, AltRandomActiveDiversity);
//in MyCalculateDiversity, latter two variables are updated as references
//save them away in non-updated variables
StartingRandomActiveDiversity = RandomActiveDiversity;
StartingAltRandomActiveDiversity = AltRandomActiveDiversity;
//3. calculate diversity from random selection at target loci
AlleleList.clear();
AlleleList.resize( AccessionsInCore.size() );
for (unsigned int j=0;j<AccessionsInCore.size();j++)
{
b = AccessionsInCore[j];
AlleleList[j] = TargetAlleleByPopList[b];
}
MyCalculateDiversity(AlleleList, TargetMaxAllelesList, Standardize, RandomTargetDiversity, AltRandomTargetDiversity);
//BEGIN OPTIMIZATION
StartingDiversity = 0; //this is the diversity recovered during the prior iteration.
plateau = 0; //count of the number of times you have found the best value, evaluates when you are
//stuck on a plateau, assuming acceptance criterion allows downhill steps
//this is the iterations step, now an indefinite loop that is broken when
//no improvement is made during the course of the optimization algorithm
//If r = kernel size = MinCoreSize then do no optimization but still calculate all variables.
if (KernelAccessionIndex.size() == r)
{
//assemble genotypes for core
//1. put together initial list
CoreAlleles.clear();
CoreAlleles.resize(r);
for (unsigned int i=0;i<r;i++)
{
b = AccessionsInCore[i];
CoreAlleles[i] = ActiveAlleleByPopList[b];
}
AlleleList = CoreAlleles;
MyCalculateDiversity(AlleleList, ActiveMaxAllelesList, Standardize, RandomActiveDiversity, AltRandomActiveDiversity);
best = RandomActiveDiversity; //best is equivalent to OptimizedActiveDiversity
AltOptimizedActiveDiversity = AltRandomActiveDiversity;
}
else
{
//do optimization
while ( true )
{
//assemble genotypes for core
//1. put together initial list
CoreAlleles.clear();
CoreAlleles.resize(r);
for (unsigned int i=0;i<r;i++)
{
b = AccessionsInCore[i];
CoreAlleles[i] = ActiveAlleleByPopList[b];
}
//2. go through all possible subsets of size r-1, one at a time, noting which is best.
//If there is a kernel, do not swap out any of those accessions (they are retained as the
//first KernelAccessionIndex.size() items in CoreAlleles). Accomplished by starting for loop
//at KernelAccessionIndex.size().
best=0;
for (unsigned int i=KernelAccessionIndex.size();i<CoreAlleles.size();i++)
{
//remove each item consecutively from the list of all populations in the core
AlleleList.clear();
TdTempList.clear();
TdTempList = CoreAlleles; //swap to temporary vector
TdTempList.erase( TdTempList.begin() + i);
AlleleList = TdTempList;
TempList2.clear();
TempList2 = AccessionsInCore;
TempList2.erase(TempList2.begin() + i);
AccessionsInSubCore = TempList2;
/*Data structure for SubCoreAlleles:
SubCore 1..r
Population 1..(r-1)
AlleleArray 1..NumLoci
--3. fuse alleles from the same locus into a single array, for all accessions, for the current subcore
--4. assemble a list of diversity (M) for each locus separately
--5. standardize the M values to the maximum possible number of alleles at that locus, and add them up to get final estimate of standardized allelic diversity in the core. then divide by the number of loci to get a number that is comparable across data sets.
--5.5. simultaneous to the calculation, keep track of which subcore is best
*/
MyCalculateDiversity(AlleleList, ActiveMaxAllelesList, Standardize, RandomActiveDiversity, AltRandomActiveDiversity);
nnew = RandomActiveDiversity;
if (nnew >= best) // >= allows sideways movement during hill climbing
{
best = nnew;
BestSubCore.clear();
BestSubCore = AccessionsInSubCore;
BestSubCoreAlleles.clear();
BestSubCoreAlleles = AlleleList;
}
} //for loop cycles thru all subcores
//reverse sort BestSubCore to support easy assembly of pared TempList below
BestSubCoreRevSorted = BestSubCore;
std::sort(BestSubCoreRevSorted.begin(), BestSubCoreRevSorted.end(), std::greater<int>());
/*
6. take the subcore with greatest diversity and consecutively add each
possible additional accession from the base collection. find the core of size r
(not r-1 subcore) that has the greatest diversity.
suppress the IDs of those accessions found in the BestSubCore from the
list of all accessions to get a list of remaining accessions.*/
TempList = AccessionNameList;
for (unsigned int k=0;k<BestSubCoreRevSorted.size();k++)
{
bsc = BestSubCoreRevSorted[k];
TempList.erase( TempList.begin() + bsc );
}
//shuffle the list of remaining accessions, so addition order is not predictable
std::random_shuffle (TempList.begin(), TempList.end());
//add each remaining accession consecutively, calculate diversity, test
//whether it is better than the prior one
best = 0;
for (unsigned int k=0;k<TempList.size();k++)
{
bsc = TempList[k];
//define the core
TempList2 = BestSubCore;
TempList2.resize( TempList2.size() + 1 );
//TempList2.push_back(i);
TempList2[TempList2.size()-1] = bsc; //add new accession to last vector element
AccessionsInCore = TempList2;
//assemble the allelelist for the core
TdTempList = BestSubCoreAlleles;
TdTempList.resize( TdTempList.size() + 1 );
//TdTempList.push_back( ActiveAlleleByPopList[i] );
TdTempList[TdTempList.size()-1] = ActiveAlleleByPopList[bsc];
AlleleList = TdTempList;
//calculate diversity
MyCalculateDiversity(AlleleList, ActiveMaxAllelesList, Standardize, nnew, TempAltOptimizedActiveDiversity);
//test whether current diversity is higher than the best diversity found so far
if (nnew >= best) // >= allows sideways movement during hill climbing
{
best = nnew;
bestcore = AccessionsInCore;
//save the alternative diversity value for the best core
AltOptimizedActiveDiversity = TempAltOptimizedActiveDiversity;
}
}
AccessionsInCore = bestcore; //define starting variable for next MSTRAT iteration
//if there has been no improvement from the prior iteration, you have reached
// the plateau and should exit the repeat
if (best == StartingDiversity)
{
plateau++;
if (plateau > 0) break;
}
//update starting value and repeat
else if (best > StartingDiversity) StartingDiversity = best;
} //while(true) endless loop
}
//7. Calculate diversity at target loci
//assemble the target loci allelelist for the accessions in the best core
AlleleList.clear();
AlleleList.resize( AccessionsInCore.size() );
for (unsigned int j=0;j<AccessionsInCore.size();j++)
{
b = AccessionsInCore[j];
AlleleList[j] = TargetAlleleByPopList[b];
}
//calculate diversity at target loci based upon the optimized core selection
MyCalculateDiversity(AlleleList, TargetMaxAllelesList, Standardize, OptimizedTargetDiversity, AltOptimizedTargetDiversity);
//8. Assemble stats for optimized core and add to output vectors
//create a list of accession names from the list of accession ID's in AccessionsInCore
sort( AccessionsInCore.begin(), AccessionsInCore.end() );
TempListStr.clear();
TempListStr.resize(r);
for (unsigned int i=0;i<AccessionsInCore.size();i++)
{
b = AccessionsInCore[i];
TempListStr[i] = FullAccessionNameList[b];
}
/***MPI: BUILD & SEND RESULTS VECTOR***/
//load the variables onto the results vectors
//no need to calculate row number, it is the same as rnr, formula saved because it might be useful later
//row = ((r - MinCoreSize)*NumReplicates) + nr - ( (NumReplicates*(SamplingFreq-1))*( (r-MinCoreSize)/SamplingFreq ) );
// (r - MinCoreSize)*NumReplicates) + nr specifies row number if SamplingFreq=1
// (NumReplicates*(SamplingFreq-1)) specifies a step value to correct when SamplingFreq>1
// ( (r-MinCoreSize)/SamplingFreq ) specifies the replicate on core size, accounting for SamplingFreq
// see file Calculation of row value.xlsx for development of the 'row' index
//put results 0-8 into a vector, resvec, return row as last item
vector<double> resvec(10);
resvec[0] = double(r);
resvec[1] = StartingRandomActiveDiversity;//RandomActiveDiversity;
resvec[2] = best; //equivalent to OptimizedActiveDiversity
resvec[3] = RandomTargetDiversity;
resvec[4] = OptimizedTargetDiversity;
resvec[5] = StartingAltRandomActiveDiversity;//AltRandomActiveDiversity;
resvec[6] = AltOptimizedActiveDiversity;
resvec[7] = AltRandomTargetDiversity;
resvec[8] = AltOptimizedTargetDiversity;
resvec[9] = double(rnr);
//cout<<"MPI_Rank="<<MPI_Rank<<"
//send result vector to master 0, send row number, rnr, as last element.
//message is tagged as 0
//here you are pointing to the first element, then returning resvec.size() doubles-
//worth of memory from that starting location.
MPI_Send(&resvec[0], resvec.size(), MPI_DOUBLE, 0, 0, MPI_COMM_WORLD);
/***MPI: END BUILD & SEND RESULTS VECTOR***/
/***MPI: BUILD & SEND MEMBERS VECTOR***/
//add row number as last item in TempListStr
TempListStr.resize(TempListStr.size()+1);
stringstream ss;
ss << rnr; //convert int to stringstream to string
TempListStr[ TempListStr.size() - 1 ] = ss.str();
//convert vector<string> to a single, ',<!>,' delimited, string
string concat;
for (unsigned int i=0;i<TempListStr.size();++i)
{
concat += TempListStr[i]; //add vector element
if (i<TempListStr.size()-1) concat += ",<!>,"; //add delimiter, except for last item
}
//convert the string to a char array
char cc[concat.size()+1];
strcpy(cc, concat.c_str());
//send the char array to master0 tagged as 1
//tagged as 1 to distinguish from result vector send
MPI_Send(&cc, sizeof(cc), MPI_CHAR, 0, 1, MPI_COMM_WORLD);
} //end for loop over rows
} //***MPI: END SEND
/*MPI: MASTER 0 WRITES OUTPUT*/
if ( procid == 0 )
{
//set up file stream for output file
ofstream output;
output.open(OutFilePath);
output.close(); //quick open close done to clear any existing file each time program is run
output.open(OutFilePath, ios::out | ios::app); //open file in append mode
output << "core size random reference diversity optimized reference diversity random target diversity optimized target diversity alt random reference diversity alt optimized reference diversity alt random target diversity alt optimized target diversity core members" << "\n";
//write out results row by row
for (int i=0;i<V1;i++)
{
//write variables
output << Results[i][0]
<< " " << Results[i][1]
<< " " << Results[i][2]
<< " " << Results[i][3]
<< " " << Results[i][4]
<< " " << Results[i][5]
<< " " << Results[i][6]
<< " " << Results[i][7]
<< " " << Results[i][8]
<< " " << "(";
//write Accessions retained
for (unsigned int j=0;j<Members[i].size();j++)
{
if ( j==(Members[i].size() - 1) )
{
//add trailing parentheses and move to next row
output << Members[i][j] << ")\n";
}
else
{
output << Members[i][j] << ",";
}
}
}
//wrap up write step
output.close();
} /***MPI: END MASTER WRITE***/
//Terminate MPI.
//MPI::Finalize ( );
}