void MrtrixPeakImageConverter< PixelType >
::GenerateData()
{
// output vector field
vtkSmartPointer<vtkCellArray> m_VtkCellArray = vtkSmartPointer<vtkCellArray>::New();
vtkSmartPointer<vtkPoints> m_VtkPoints = vtkSmartPointer<vtkPoints>::New();
Vector<float, 4> spacing4 = m_InputImage->GetSpacing();
Point<float, 4> origin4 = m_InputImage->GetOrigin();
Matrix<double, 4, 4> direction4 = m_InputImage->GetDirection();
ImageRegion<4> imageRegion4 = m_InputImage->GetLargestPossibleRegion();
Vector<float, 3> spacing3;
Point<float, 3> origin3;
Matrix<double, 3, 3> direction3;
ImageRegion<3> imageRegion3;
spacing3[0] = spacing4[0]; spacing3[1] = spacing4[1]; spacing3[2] = spacing4[2];
origin3[0] = origin4[0]; origin3[1] = origin4[1]; origin3[2] = origin4[2];
for (int r=0; r<3; r++)
for (int c=0; c<3; c++)
direction3[r][c] = direction4[r][c];
imageRegion3.SetSize(0, imageRegion4.GetSize()[0]);
imageRegion3.SetSize(1, imageRegion4.GetSize()[1]);
imageRegion3.SetSize(2, imageRegion4.GetSize()[2]);
double minSpacing = spacing3[0];
if (spacing3[1]<minSpacing)
minSpacing = spacing3[1];
if (spacing3[2]<minSpacing)
minSpacing = spacing3[2];
m_DirectionImageContainer = DirectionImageContainerType::New();
typedef ImageRegionConstIterator< InputImageType > InputIteratorType;
int x = m_InputImage->GetLargestPossibleRegion().GetSize(0);
int y = m_InputImage->GetLargestPossibleRegion().GetSize(1);
int z = m_InputImage->GetLargestPossibleRegion().GetSize(2);
int numDirs = m_InputImage->GetLargestPossibleRegion().GetSize(3)/3;
m_NumDirectionsImage = ItkUcharImgType::New();
m_NumDirectionsImage->SetSpacing( spacing3 );
m_NumDirectionsImage->SetOrigin( origin3 );
m_NumDirectionsImage->SetDirection( direction3 );
m_NumDirectionsImage->SetRegions( imageRegion3 );
m_NumDirectionsImage->Allocate();
m_NumDirectionsImage->FillBuffer(0);
for (int i=0; i<numDirs; i++)
{
ItkDirectionImageType::Pointer directionImage = ItkDirectionImageType::New();
directionImage->SetSpacing( spacing3 );
directionImage->SetOrigin( origin3 );
directionImage->SetDirection( direction3 );
directionImage->SetRegions( imageRegion3 );
directionImage->Allocate();
Vector< PixelType, 3 > nullVec; nullVec.Fill(0.0);
directionImage->FillBuffer(nullVec);
for (int a=0; a<x; a++)
for (int b=0; b<y; b++)
for (int c=0; c<z; c++)
{
// generate vector field
typename InputImageType::IndexType index;
index.SetElement(0,a);
index.SetElement(1,b);
index.SetElement(2,c);
vnl_vector<double> dirVec; dirVec.set_size(4);
for (int k=0; k<3; k++)
{
index.SetElement(3,k+i*3);
dirVec[k] = m_InputImage->GetPixel(index);
}
dirVec[3] = 0;
vtkSmartPointer<vtkPolyLine> container = vtkSmartPointer<vtkPolyLine>::New();
itk::ContinuousIndex<double, 4> center;
center[0] = index[0];
center[1] = index[1];
center[2] = index[2];
center[3] = 0;
itk::Point<double, 4> worldCenter;
m_InputImage->TransformContinuousIndexToPhysicalPoint( center, worldCenter );
switch (m_NormalizationMethod)
{
case NO_NORM:
break;
case SINGLE_VEC_NORM:
dirVec.normalize();
break;
}
dirVec.normalize();
dirVec = m_InputImage->GetDirection()*dirVec;
itk::Point<double> worldStart;
worldStart[0] = worldCenter[0]-dirVec[0]/2 * minSpacing;
worldStart[1] = worldCenter[1]-dirVec[1]/2 * minSpacing;
worldStart[2] = worldCenter[2]-dirVec[2]/2 * minSpacing;
vtkIdType id = m_VtkPoints->InsertNextPoint(worldStart.GetDataPointer());
container->GetPointIds()->InsertNextId(id);
itk::Point<double> worldEnd;
worldEnd[0] = worldCenter[0]+dirVec[0]/2 * minSpacing;
worldEnd[1] = worldCenter[1]+dirVec[1]/2 * minSpacing;
worldEnd[2] = worldCenter[2]+dirVec[2]/2 * minSpacing;
id = m_VtkPoints->InsertNextPoint(worldEnd.GetDataPointer());
container->GetPointIds()->InsertNextId(id);
m_VtkCellArray->InsertNextCell(container);
// generate direction image
typename ItkDirectionImageType::IndexType index2;
index2[0] = a; index2[1] = b; index2[2] = c;
Vector< PixelType, 3 > pixel;
pixel.SetElement(0, dirVec[0]);
pixel.SetElement(1, dirVec[1]);
pixel.SetElement(2, dirVec[2]);
directionImage->SetPixel(index2, pixel);
if (dirVec.magnitude()>0.0001)
m_NumDirectionsImage->SetPixel(index2, m_NumDirectionsImage->GetPixel(index2)+1);
}
m_DirectionImageContainer->InsertElement(m_DirectionImageContainer->Size(), directionImage);
}
vtkSmartPointer<vtkPolyData> directionsPolyData = vtkSmartPointer<vtkPolyData>::New();
directionsPolyData->SetPoints(m_VtkPoints);
directionsPolyData->SetLines(m_VtkCellArray);
m_OutputFiberBundle = mitk::FiberBundleX::New(directionsPolyData);
}
void TractsToVectorImageFilter< PixelType >::GenerateData()
{
mitk::BaseGeometry::Pointer geometry = m_FiberBundle->GetGeometry();
// calculate new image parameters
itk::Vector<double> spacing;
itk::Point<double> origin;
itk::Matrix<double, 3, 3> direction;
ImageRegion<3> imageRegion;
if (!m_MaskImage.IsNull())
{
spacing = m_MaskImage->GetSpacing();
imageRegion = m_MaskImage->GetLargestPossibleRegion();
origin = m_MaskImage->GetOrigin();
direction = m_MaskImage->GetDirection();
}
else
{
spacing = geometry->GetSpacing();
origin = geometry->GetOrigin();
mitk::BaseGeometry::BoundsArrayType bounds = geometry->GetBounds();
origin[0] += bounds.GetElement(0);
origin[1] += bounds.GetElement(2);
origin[2] += bounds.GetElement(4);
for (int i=0; i<3; i++)
for (int j=0; j<3; j++)
direction[j][i] = geometry->GetMatrixColumn(i)[j];
imageRegion.SetSize(0, geometry->GetExtent(0));
imageRegion.SetSize(1, geometry->GetExtent(1));
imageRegion.SetSize(2, geometry->GetExtent(2));
m_MaskImage = ItkUcharImgType::New();
m_MaskImage->SetSpacing( spacing );
m_MaskImage->SetOrigin( origin );
m_MaskImage->SetDirection( direction );
m_MaskImage->SetRegions( imageRegion );
m_MaskImage->Allocate();
m_MaskImage->FillBuffer(1);
}
OutputImageType::RegionType::SizeType outImageSize = imageRegion.GetSize();
m_OutImageSpacing = m_MaskImage->GetSpacing();
m_ClusteredDirectionsContainer = ContainerType::New();
// initialize num directions image
m_NumDirectionsImage = ItkUcharImgType::New();
m_NumDirectionsImage->SetSpacing( spacing );
m_NumDirectionsImage->SetOrigin( origin );
m_NumDirectionsImage->SetDirection( direction );
m_NumDirectionsImage->SetRegions( imageRegion );
m_NumDirectionsImage->Allocate();
m_NumDirectionsImage->FillBuffer(0);
// initialize direction images
m_DirectionImageContainer = DirectionImageContainerType::New();
// resample fiber bundle
double minSpacing = 1;
if(m_OutImageSpacing[0]<m_OutImageSpacing[1] && m_OutImageSpacing[0]<m_OutImageSpacing[2])
minSpacing = m_OutImageSpacing[0];
else if (m_OutImageSpacing[1] < m_OutImageSpacing[2])
minSpacing = m_OutImageSpacing[1];
else
minSpacing = m_OutImageSpacing[2];
if (m_UseWorkingCopy)
m_FiberBundle = m_FiberBundle->GetDeepCopy();
// resample fiber bundle for sufficient voxel coverage
m_FiberBundle->ResampleSpline(minSpacing/10);
// iterate over all fibers
vtkSmartPointer<vtkPolyData> fiberPolyData = m_FiberBundle->GetFiberPolyData();
int numFibers = m_FiberBundle->GetNumFibers();
m_DirectionsContainer = ContainerType::New();
VectorContainer< unsigned int, std::vector< double > >::Pointer peakLengths = VectorContainer< unsigned int, std::vector< double > >::New();
MITK_INFO << "Generating directions from tractogram";
boost::progress_display disp(numFibers);
for( int i=0; i<numFibers; i++ )
{
++disp;
vtkCell* cell = fiberPolyData->GetCell(i);
int numPoints = cell->GetNumberOfPoints();
vtkPoints* points = cell->GetPoints();
if (numPoints<2)
continue;
vnl_vector_fixed<double, 3> dir;
itk::Point<double, 3> worldPos;
vnl_vector<double> v;
float fiberWeight = m_FiberBundle->GetFiberWeight(i);
for( int j=0; j<numPoints-1; j++)
{
// get current position along fiber in world coordinates
double* temp = points->GetPoint(j);
worldPos = GetItkPoint(temp);
itk::Index<3> index;
m_MaskImage->TransformPhysicalPointToIndex(worldPos, index);
if (!m_MaskImage->GetLargestPossibleRegion().IsInside(index) || m_MaskImage->GetPixel(index)==0)
continue;
// get fiber tangent direction at this position
v = GetVnlVector(temp);
dir = GetVnlVector(points->GetPoint(j+1))-v;
if (dir.is_zero())
continue;
dir.normalize();
// add direction to container
unsigned int idx = index[0] + outImageSize[0]*(index[1] + outImageSize[1]*index[2]);
DirectionContainerType::Pointer dirCont;
if (m_DirectionsContainer->IndexExists(idx))
{
peakLengths->ElementAt(idx).push_back(fiberWeight);
dirCont = m_DirectionsContainer->GetElement(idx);
if (dirCont.IsNull())
{
dirCont = DirectionContainerType::New();
dirCont->push_back(dir);
m_DirectionsContainer->InsertElement(idx, dirCont);
}
else
dirCont->push_back(dir);
}
else
{
dirCont = DirectionContainerType::New();
dirCont->push_back(dir);
m_DirectionsContainer->InsertElement(idx, dirCont);
std::vector< double > lengths; lengths.push_back(fiberWeight);
peakLengths->InsertElement(idx, lengths);
}
}
}
vtkSmartPointer<vtkCellArray> m_VtkCellArray = vtkSmartPointer<vtkCellArray>::New();
vtkSmartPointer<vtkPoints> m_VtkPoints = vtkSmartPointer<vtkPoints>::New();
itk::ImageRegionIterator<ItkUcharImgType> dirIt(m_NumDirectionsImage, m_NumDirectionsImage->GetLargestPossibleRegion());
MITK_INFO << "Clustering directions";
boost::progress_display disp2(outImageSize[0]*outImageSize[1]*outImageSize[2]);
while(!dirIt.IsAtEnd())
{
++disp2;
OutputImageType::IndexType index = dirIt.GetIndex();
int idx = index[0]+(index[1]+index[2]*outImageSize[1])*outImageSize[0];
if (!m_DirectionsContainer->IndexExists(idx))
{
++dirIt;
continue;
}
DirectionContainerType::Pointer dirCont = m_DirectionsContainer->GetElement(idx);
if (dirCont.IsNull() || dirCont->empty())
{
++dirIt;
continue;
}
// std::vector< double > lengths; lengths.resize(dirCont->size(), 1); // all peaks have size 1
DirectionContainerType::Pointer directions;
if (m_MaxNumDirections>0)
{
directions = FastClustering(dirCont, peakLengths->GetElement(idx));
std::sort( directions->begin(), directions->end(), CompareVectorLengths );
}
else
directions = dirCont;
unsigned int numDir = directions->size();
if (m_MaxNumDirections>0 && numDir>m_MaxNumDirections)
numDir = m_MaxNumDirections;
int count = 0;
for (unsigned int i=0; i<numDir; i++)
{
vtkSmartPointer<vtkPolyLine> container = vtkSmartPointer<vtkPolyLine>::New();
itk::ContinuousIndex<double, 3> center;
center[0] = index[0];
center[1] = index[1];
center[2] = index[2];
itk::Point<double> worldCenter;
m_MaskImage->TransformContinuousIndexToPhysicalPoint( center, worldCenter );
DirectionType dir = directions->at(i);
if (dir.magnitude()<m_SizeThreshold)
continue;
if (m_NormalizeVectors)
dir.normalize();
count++;
if (m_CreateDirectionImages && i<10)
{
if (i==m_DirectionImageContainer->size())
{
ItkDirectionImageType::Pointer directionImage = ItkDirectionImageType::New();
directionImage->SetSpacing( spacing );
directionImage->SetOrigin( origin );
directionImage->SetDirection( direction );
directionImage->SetRegions( imageRegion );
directionImage->Allocate();
Vector< float, 3 > nullVec; nullVec.Fill(0.0);
directionImage->FillBuffer(nullVec);
m_DirectionImageContainer->InsertElement(i, directionImage);
}
// set direction image pixel
ItkDirectionImageType::Pointer directionImage = m_DirectionImageContainer->GetElement(i);
Vector< float, 3 > pixel;
pixel.SetElement(0, dir[0]);
pixel.SetElement(1, dir[1]);
pixel.SetElement(2, dir[2]);
directionImage->SetPixel(index, pixel);
}
// add direction to vector field (with spacing compensation)
itk::Point<double> worldStart;
worldStart[0] = worldCenter[0]-dir[0]/2*minSpacing;
worldStart[1] = worldCenter[1]-dir[1]/2*minSpacing;
worldStart[2] = worldCenter[2]-dir[2]/2*minSpacing;
vtkIdType id = m_VtkPoints->InsertNextPoint(worldStart.GetDataPointer());
container->GetPointIds()->InsertNextId(id);
itk::Point<double> worldEnd;
worldEnd[0] = worldCenter[0]+dir[0]/2*minSpacing;
worldEnd[1] = worldCenter[1]+dir[1]/2*minSpacing;
worldEnd[2] = worldCenter[2]+dir[2]/2*minSpacing;
id = m_VtkPoints->InsertNextPoint(worldEnd.GetDataPointer());
container->GetPointIds()->InsertNextId(id);
m_VtkCellArray->InsertNextCell(container);
}
dirIt.Set(count);
++dirIt;
}
vtkSmartPointer<vtkPolyData> directionsPolyData = vtkSmartPointer<vtkPolyData>::New();
directionsPolyData->SetPoints(m_VtkPoints);
directionsPolyData->SetLines(m_VtkCellArray);
m_OutputFiberBundle = mitk::FiberBundle::New(directionsPolyData);
}