// If `pickup_new_runs` is true we pick up runs starting at this supernode
static inline bool gcrawler_stop_at_ref_covg(const GraphCache *cache,
                                             const GCacheStep *step,
                                             BreakpointCaller *caller,
                                             KOccurRunBuffer *koruns,
                                             KOccurRunBuffer *koruns_ended,
                                             bool pickup_new_runs)
{
  GCacheSnode *snode = graph_cache_snode(cache, step->supernode);
  GCachePath *path = graph_cache_path(cache, step->pathid);
  const dBNode *nodes = graph_cache_first_node(cache, snode);
  bool forward = (step->orient == FORWARD);

  // Use index of last step as qoffset
  size_t qoffset = path->num_steps-1;

  // Kmer occurance runs are added to koruns_3p_ended only if they end and are
  // longer than the mininum length in kmers (caller->min_ref_nkmers)
  kograph_filter_extend(caller->kograph,
                        nodes, snode->num_nodes, forward,
                        caller->min_ref_nkmers, qoffset,
                        koruns, koruns_ended,
                        pickup_new_runs);

  size_t i, min_run_qoffset = SIZE_MAX, min_ended_run_qoffset = SIZE_MAX;
  for(i = 0; i < koruns->len; i++)
    min_run_qoffset = MIN2(min_run_qoffset, koruns->data[i].qoffset);

  // Stop if all our earliest runs have finished
  for(i = 0; i < koruns_ended->len; i++) {
    min_ended_run_qoffset = MIN2(min_ended_run_qoffset, koruns_ended->data[i].qoffset);
  }

  // Continue if...
  return min_run_qoffset <= min_ended_run_qoffset;
}
Example #2
0
static inline void walk_supernode_end(const GraphCache *cache,
                                      const GCacheSnode *snode,
                                      Orientation snorient,
                                      GraphWalker *wlk)
{
  // Only need to traverse the first and last nodes of a supernode
  const dBNode *first = graph_cache_first_node(cache, snode);
  const dBNode *last = graph_cache_last_node(cache, snode);
  dBNode lastnode;
  size_t num_nodes = last - first + 1;

  if(num_nodes > 1) {
    lastnode = (snorient == FORWARD ? *last : db_node_reverse(*first));
    graph_walker_jump_along_snode(wlk, lastnode, num_nodes);
  }
}
Example #3
0
void graph_crawler_reset_rpt_walker(RepeatWalker *rptwlk,
                                    const GraphCache *cache, uint32_t pathid)
{
  rpt_walker_fast_clear(rptwlk, NULL, 0);

  const GCachePath *path = graph_cache_path(cache, pathid);
  const GCacheStep *step = graph_cache_step(cache, path->first_step), *endstep;
  const GCacheSnode *snode;
  const dBNode *node0, *node1;

  // Loop over supernodes in the path
  for(endstep = step + path->num_steps; step < endstep; step++)
  {
    // We don't care about orientation here
    snode = graph_cache_snode(cache, step->supernode);
    node0 = graph_cache_first_node(cache, snode);
    node1 = graph_cache_last_node(cache, snode);
    rpt_walker_fast_clear_single_node(rptwlk, *node0);
    rpt_walker_fast_clear_single_node(rptwlk, *node1);
  }
}