void DemonsRegistration::GenerateData2(const itk::Image<TPixel, VImageDimension>* itkImage1)
{
typedef typename itk::Image< TPixel, VImageDimension > FixedImageType;
typedef typename itk::Image< TPixel, VImageDimension > MovingImageType;
typedef float InternalPixelType;
typedef typename itk::Image< InternalPixelType, VImageDimension > InternalImageType;
typedef typename itk::CastImageFilter< FixedImageType,
InternalImageType > FixedImageCasterType;
typedef typename itk::CastImageFilter< MovingImageType,
InternalImageType > MovingImageCasterType;
typedef typename itk::Image< InternalPixelType, VImageDimension > InternalImageType;
typedef typename itk::Vector< float, VImageDimension > VectorPixelType;
typedef typename itk::Image< VectorPixelType, VImageDimension > DeformationFieldType;
typedef typename itk::DemonsRegistrationFilter<
InternalImageType,
InternalImageType,
DeformationFieldType> RegistrationFilterType;
typedef typename itk::WarpImageFilter<
MovingImageType,
MovingImageType,
DeformationFieldType > WarperType;
typedef typename itk::LinearInterpolateImageFunction<
MovingImageType,
double > InterpolatorType;
typedef TPixel OutputPixelType;
typedef typename itk::Image< OutputPixelType, VImageDimension > OutputImageType;
typedef typename itk::CastImageFilter<
MovingImageType,
OutputImageType > CastFilterType;
typedef typename itk::ImageFileWriter< OutputImageType > WriterType;
typedef typename itk::ImageFileWriter< DeformationFieldType > FieldWriterType;
typename FixedImageType::Pointer fixedImage = FixedImageType::New();
mitk::CastToItkImage(m_ReferenceImage, fixedImage);
typename MovingImageType::ConstPointer movingImage = itkImage1;
if (fixedImage.IsNotNull() && movingImage.IsNotNull())
{
typename RegistrationFilterType::Pointer filter = RegistrationFilterType::New();
this->AddStepsToDo(4);
typename itk::ReceptorMemberCommand<DemonsRegistration>::Pointer command = itk::ReceptorMemberCommand<DemonsRegistration>::New();
command->SetCallbackFunction(this, &DemonsRegistration::SetProgress);
filter->AddObserver( itk::IterationEvent(), command );
typename FixedImageCasterType::Pointer fixedImageCaster = FixedImageCasterType::New();
fixedImageCaster->SetInput(fixedImage);
filter->SetFixedImage( fixedImageCaster->GetOutput() );
typename MovingImageCasterType::Pointer movingImageCaster = MovingImageCasterType::New();
movingImageCaster->SetInput(movingImage);
filter->SetMovingImage(movingImageCaster->GetOutput());
filter->SetNumberOfIterations( m_Iterations );
filter->SetStandardDeviations( m_StandardDeviation );
filter->Update();
typename WarperType::Pointer warper = WarperType::New();
typename InterpolatorType::Pointer interpolator = InterpolatorType::New();
warper->SetInput( movingImage );
warper->SetInterpolator( interpolator );
warper->SetOutputSpacing( fixedImage->GetSpacing() );
warper->SetOutputOrigin( fixedImage->GetOrigin() );
warper->SetOutputDirection( fixedImage->GetDirection());
warper->SetDisplacementField( filter->GetOutput() );
warper->Update();
Image::Pointer outputImage = this->GetOutput();
mitk::CastToMitkImage( warper->GetOutput(), outputImage );
typename WriterType::Pointer writer = WriterType::New();
typename CastFilterType::Pointer caster = CastFilterType::New();
writer->SetFileName( m_ResultName );
caster->SetInput( warper->GetOutput() );
writer->SetInput( caster->GetOutput() );
if(m_SaveResult)
{
writer->Update();
}
if (VImageDimension == 2)
{
typedef DeformationFieldType VectorImage2DType;
typedef typename DeformationFieldType::PixelType Vector2DType;
typename VectorImage2DType::ConstPointer vectorImage2D = filter->GetOutput();
typename VectorImage2DType::RegionType region2D = vectorImage2D->GetBufferedRegion();
typename VectorImage2DType::IndexType index2D = region2D.GetIndex();
typename VectorImage2DType::SizeType size2D = region2D.GetSize();
typedef typename itk::Vector< float, 3 > Vector3DType;
typedef typename itk::Image< Vector3DType, 3 > VectorImage3DType;
typedef typename itk::ImageFileWriter< VectorImage3DType > WriterType;
typename WriterType::Pointer writer3D = WriterType::New();
typename VectorImage3DType::Pointer vectorImage3D = VectorImage3DType::New();
typename VectorImage3DType::RegionType region3D;
typename VectorImage3DType::IndexType index3D;
typename VectorImage3DType::SizeType size3D;
index3D[0] = index2D[0];
index3D[1] = index2D[1];
index3D[2] = 0;
size3D[0] = size2D[0];
size3D[1] = size2D[1];
size3D[2] = 1;
region3D.SetSize( size3D );
region3D.SetIndex( index3D );
typename VectorImage2DType::SpacingType spacing2D = vectorImage2D->GetSpacing();
typename VectorImage3DType::SpacingType spacing3D;
spacing3D[0] = spacing2D[0];
spacing3D[1] = spacing2D[1];
spacing3D[2] = 1.0;
vectorImage3D->SetSpacing( spacing3D );
vectorImage3D->SetRegions( region3D );
vectorImage3D->Allocate();
typedef typename itk::ImageRegionConstIterator< VectorImage2DType > Iterator2DType;
typedef typename itk::ImageRegionIterator< VectorImage3DType > Iterator3DType;
Iterator2DType it2( vectorImage2D, region2D );
Iterator3DType it3( vectorImage3D, region3D );
it2.GoToBegin();
it3.GoToBegin();
Vector2DType vector2D;
Vector3DType vector3D;
vector3D[2] = 0; // set Z component to zero.
while( !it2.IsAtEnd() )
{
vector2D = it2.Get();
vector3D[0] = vector2D[0];
vector3D[1] = vector2D[1];
it3.Set( vector3D );
++it2;
++it3;
}
writer3D->SetInput( vectorImage3D );
m_DeformationField = vectorImage3D;
writer3D->SetFileName( m_FieldName );
try
{
if(m_SaveField)
{
writer3D->Update();
}
}
catch( itk::ExceptionObject & excp )
{
MITK_ERROR << excp << std::endl;
}
}
else
{
typename FieldWriterType::Pointer fieldwriter = FieldWriterType::New();
fieldwriter->SetFileName(m_FieldName);
fieldwriter->SetInput( filter->GetOutput() );
m_DeformationField = (itk::Image<itk::Vector<float, 3>,3> *)(filter->GetOutput());
if(m_SaveField)
{
fieldwriter->Update();
}
}
this->SetRemainingProgress(4);
}
}
typename TImage::Pointer modelBasedImageToImageRegistration(std::string referenceFilename,
std::string targetFilename,
typename TStatisticalModelType::Pointer model,
std::string outputDfFilename,
unsigned numberOfIterations){
typedef itk::ImageFileReader<TImage> ImageReaderType;
typedef itk::InterpolatingStatisticalDeformationModelTransform<TRepresenter, double, VImageDimension> TransformType;
typedef itk::LBFGSOptimizer OptimizerType;
typedef itk::ImageRegistrationMethod<TImage, TImage> RegistrationFilterType;
typedef itk::WarpImageFilter< TImage, TImage, TVectorImage > WarperType;
typedef itk::LinearInterpolateImageFunction< TImage, double > InterpolatorType;
typename ImageReaderType::Pointer referenceReader = ImageReaderType::New();
referenceReader->SetFileName(referenceFilename.c_str());
referenceReader->Update();
typename TImage::Pointer referenceImage = referenceReader->GetOutput();
referenceImage->Update();
typename ImageReaderType::Pointer targetReader = ImageReaderType::New();
targetReader->SetFileName(targetFilename.c_str());
targetReader->Update();
typename TImage::Pointer targetImage = targetReader->GetOutput();
targetImage->Update();
// do the fitting
typename TransformType::Pointer transform = TransformType::New();
transform->SetStatisticalModel(model);
transform->SetIdentity();
// Setting up the fitting
OptimizerType::Pointer optimizer = OptimizerType::New();
optimizer->MinimizeOn();
optimizer->SetMaximumNumberOfFunctionEvaluations(numberOfIterations);
typedef IterationStatusObserver ObserverType;
ObserverType::Pointer observer = ObserverType::New();
optimizer->AddObserver( itk::IterationEvent(), observer );
typename TMetricType::Pointer metric = TMetricType::New();
typename InterpolatorType::Pointer interpolator = InterpolatorType::New();
typename RegistrationFilterType::Pointer registration = RegistrationFilterType::New();
registration->SetInitialTransformParameters(transform->GetParameters());
registration->SetMetric(metric);
registration->SetOptimizer( optimizer );
registration->SetTransform( transform );
registration->SetInterpolator( interpolator );
registration->SetFixedImage( targetImage );
registration->SetFixedImageRegion(targetImage->GetBufferedRegion() );
registration->SetMovingImage( referenceImage );
try {
std::cout << "Performing registration... " << std::flush;
registration->Update();
std::cout << "[done]" << std::endl;
} catch ( itk::ExceptionObject& o ) {
std::cout << "caught exception " << o << std::endl;
}
typename TVectorImage::Pointer df = model->DrawSample(transform->GetCoefficients());
// write deformation field
if(outputDfFilename.size()>0){
typename itk::ImageFileWriter<TVectorImage>::Pointer df_writer = itk::ImageFileWriter<TVectorImage>::New();
df_writer->SetFileName(outputDfFilename);
df_writer->SetInput(df);
df_writer->Update();
}
// warp reference
std::cout << "Warping reference... " << std::flush;
typename WarperType::Pointer warper = WarperType::New();
warper->SetInput(referenceImage );
warper->SetInterpolator( interpolator );
warper->SetOutputSpacing( targetImage->GetSpacing() );
warper->SetOutputOrigin( targetImage->GetOrigin() );
warper->SetOutputDirection( targetImage->GetDirection() );
warper->SetDisplacementField( df );
warper->Update();
std::cout << "[done]" << std::endl;
return warper->GetOutput();
}