void SQRCheckButton::OnLButtonClick( uint32 nFlags, int32 x, int32 y )
{
//处理分组状态
//复选框,可同时选多个
if( GetStyle() & BTN_CHECK )
{
//切换状态
m_bCheck = !m_bCheck;
OnCheck( m_bCheck );
}
//单选框，同时只有一个可被选中
else if( GetStyle() & BTN_RADIO )
SetCheck( true );
SQRButton::OnLButtonClick( nFlags, x, y );
}
void SQRCheckButton::SetCheck( bool bCheck )
{
m_bCheck = bCheck;
//单选框，同时只有一个可被选中
if( m_bCheck && (GetStyle() & BTN_RADIO) && GetGroupID() >= 0 )
{
SQRWnd* pBrother = GetFirstBrother();
while( pBrother )
{
if( GetClassName() == pBrother->GetClassName() && pBrother != this &&
GetGroupID() == static_cast<SQRCheckButton*>(pBrother)->GetGroupID() )
static_cast<SQRCheckButton*>(pBrother)->SetCheck( false );
pBrother = pBrother->FindNextWnd();
}
}
OnCheck( m_bCheck );
}
BMARefinerOptionsDialog::BMARefinerOptionsDialog(wxWindow* parent,
const GeneralRefinerParams& current_genl,
const LeaveOneOutParams& current_loo,
const BlockEditingParams& current_be,
const vector < string >& titles) :
wxDialog(parent, -1, wxT("Alignment Refiner Options"), wxPoint(100,100), wxDefaultSize, wxDEFAULT_DIALOG_STYLE),
rowTitles(titles)
{
wxBoxSizer *hSizer;
rowsToExclude = current_loo.rowsToExclude;
// wxScrolledWindow *panel = new wxScrolledWindow(this, -1, wxDefaultPosition, wxDefaultSize, wxVSCROLL);
wxPanel *panel = new wxPanel(this, -1);
// Dialog heading
// wxBoxSizer *item1 = new wxBoxSizer( wxHORIZONTAL );
// wxStaticText *item2 = new wxStaticText( panel, ID_TEXT, wxT("Alignment Refiner Options"), wxDefaultPosition, wxDefaultSize, wxALIGN_CENTRE );
// item2->SetFont( wxFont( 16, wxROMAN, wxNORMAL, wxNORMAL ) );
// item1->Add( item2, 0, wxALIGN_CENTER|wxALL, 15 );
// ************************************************** //
// Start GUI elements for general parameters
// Cycles/trials
wxStaticBox *item60 = new wxStaticBox( panel, -1, wxT("General Refiner Parameters") );
item60->SetFont( wxFont( 10, wxROMAN, wxNORMAL, wxBOLD ) );
wxStaticBoxSizer *item64 = new wxStaticBoxSizer( item60, wxVERTICAL );
wxFlexGridSizer *item61 = new wxFlexGridSizer( 2, 0, 0 );
item61->AddGrowableCol( 1 );
// # of cycles/trial
wxStaticText *item63 = new wxStaticText( panel, ID_TEXT, wxT("Number of refinement cycles: "), wxDefaultPosition, wxDefaultSize, 0 );
item61->Add( item63, 0, wxALIGN_CENTER_VERTICAL|wxALL, 5 );
hSizer = new wxBoxSizer(wxHORIZONTAL);
nCyclesSpin = new IntegerSpinCtrl(panel,
1, 10, 1, current_genl.nCycles,
wxDefaultPosition, wxSize(80, SPIN_CTRL_HEIGHT), 0,
wxDefaultPosition, wxSize(-1, SPIN_CTRL_HEIGHT));
hSizer->Add(nCyclesSpin->GetTextCtrl(), 0, wxALIGN_RIGHT|wxLEFT|wxTOP|wxBOTTOM, 5);
hSizer->Add(nCyclesSpin->GetSpinButton(), 0, wxALIGN_LEFT|wxRIGHT|wxTOP|wxBOTTOM, 5);
item61->Add(hSizer, 0, wxALIGN_RIGHT);
// Order of phases (LOO->BE or BE->LOO)
int initialPOIndex = (current_genl.lnoFirst) ? 0 : 1;
wxStaticText *item65 = new wxStaticText( panel, ID_TEXT, wxT("Phase order:"), wxDefaultPosition, wxDefaultSize, 0 );
item61->Add( item65, 0, wxALIGN_CENTER_VERTICAL|wxALL, 5 );
phaseOrderCombo = new wxComboBox( panel, ID_PHASE_ORDER_COMBOBOX, phaseOrderStrings[initialPOIndex], wxDefaultPosition, wxDefaultSize, sizeof(phaseOrderStrings)/sizeof(phaseOrderStrings[0]), phaseOrderStrings, wxCB_READONLY );
item61->Add( phaseOrderCombo, 0, wxALIGN_RIGHT|wxALL, 5 );
item64->Add( item61, 0, wxALIGN_CENTER_VERTICAL, 0 );
// ************************************************** //
// Start GUI elements for LOO/LNO block shifting parameters
wxStaticBox *item4 = new wxStaticBox( panel, -1, wxT("Block Shifting Parameters") );
item4->SetFont( wxFont( 10, wxROMAN, wxNORMAL, wxBOLD ) );
wxStaticBoxSizer *item3 = new wxStaticBoxSizer( item4, wxVERTICAL );
wxFlexGridSizer *item5 = new wxFlexGridSizer( 2, 0, 0 );
item5->AddGrowableCol( 1 );
// Do LOO/LNO???
wxStaticText *item66 = new wxStaticText( panel, ID_TEXT, wxT("Shift blocks?"), wxDefaultPosition, wxDefaultSize, 0 );
item5->Add( item66, 0, wxALIGN_CENTER_VERTICAL|wxALL, 5 );
doLooCheck = new wxCheckBox( panel, ID_DO_LOO_CHECKBOX, wxT(""), wxDefaultPosition, wxDefaultSize, 0 );
doLooCheck->SetValue(current_loo.doLOO);
item5->Add( doLooCheck, 0, wxALIGN_RIGHT|wxALL, 5 );
// LNO parameter (1 == L00; >1 = group size for running LNO)
wxStaticText *item12 = new wxStaticText( panel, ID_TEXT, wxT("Group rows in sets of:"), wxDefaultPosition, wxDefaultSize, wxALIGN_CENTRE );
item5->Add( item12, 0, wxALIGN_CENTER_VERTICAL|wxALL, 5 );
hSizer = new wxBoxSizer(wxHORIZONTAL);
lnoSpin = new IntegerSpinCtrl(panel,
1, 50, 1, current_loo.lno,
wxDefaultPosition, wxSize(80, SPIN_CTRL_HEIGHT), 0,
wxDefaultPosition, wxSize(-1, SPIN_CTRL_HEIGHT));
hSizer->Add(lnoSpin->GetTextCtrl(), 0, wxALIGN_RIGHT|wxLEFT|wxTOP|wxBOTTOM, 5);
hSizer->Add(lnoSpin->GetSpinButton(), 0, wxALIGN_LEFT|wxRIGHT|wxTOP|wxBOTTOM, 5);
item5->Add(hSizer, 0, wxALIGN_RIGHT);
// Blank space
wxStaticText *item24 = new wxStaticText( panel, ID_TEXT, wxT(""), wxDefaultPosition, wxDefaultSize, 0 );
item5->Add( item24, 0, wxALIGN_CENTER, 5 );
wxStaticText *item25 = new wxStaticText( panel, ID_TEXT, wxT(""), wxDefaultPosition, wxDefaultSize, 0 );
item5->Add( item25, 0, wxALIGN_CENTER, 5 );
// perform LOO/LNO on structures?
wxStaticText *item6 = new wxStaticText( panel, ID_TEXT, wxT("Refine rows with structure:"), wxDefaultPosition, wxDefaultSize, 0 );
item5->Add( item6, 0, wxALIGN_CENTER_VERTICAL|wxALL, 5 );
// wxStaticText *item7 = new wxStaticText( panel, ID_TEXT, wxT(""), wxDefaultPosition, wxDefaultSize, 0 );
// item5->Add( item7, 0, wxALIGN_CENTRE|wxLEFT|wxTOP|wxBOTTOM, 5 );
fixStructCheck = new wxCheckBox( panel, ID_FIX_STRUCT_CHECKBOX, wxT(""), wxDefaultPosition, wxDefaultSize, 0 );
unsigned int nStructs = GetNumEmptyRowTitles(false);
bool hasNoStructures = (nStructs == 0);
bool hasOnlyStructures = (nStructs == rowTitles.size() - 1);
if (hasNoStructures)
fixStructCheck->SetValue(false);
else if (hasOnlyStructures)
fixStructCheck->SetValue(true);
else
fixStructCheck->SetValue(!current_loo.fixStructures);
item5->Add( fixStructCheck, 0, wxALIGN_RIGHT|wxALL, 5 );
// align all non-structured rows?
wxStaticText *item90 = new wxStaticText( panel, ID_TEXT, wxT("Refine all unstructured rows:"), wxDefaultPosition, wxDefaultSize, 0 );
item5->Add( item90, 0, wxALIGN_CENTER_VERTICAL|wxALL, 5 );
// wxStaticText *item100 = new wxStaticText( panel, ID_TEXT, wxT(""), wxDefaultPosition, wxDefaultSize, 0 );
// item5->Add( item100, 0, wxALIGN_CENTRE|wxLEFT|wxTOP|wxBOTTOM, 5 );
allUnstSeqCheck = new wxCheckBox( panel, ID_ALL_UNST_SEQ_CHECKBOX, wxT(""), wxDefaultPosition, wxDefaultSize, 0 );
allUnstSeqCheck->SetValue(!hasOnlyStructures);
item5->Add( allUnstSeqCheck, 0, wxALIGN_RIGHT|wxALL, 5 );
// Order of row selection in LOO/LNO
int initialSelOrderIndex = (int) current_loo.selectorCode;
// wxStaticText *item68 = new wxStaticText( panel, ID_TEXT, wxT("Row selection order:"), wxDefaultPosition, wxDefaultSize, 0 );
// item5->Add( item68, 0, wxALIGN_CENTER_VERTICAL|wxALL, 5 );
looSelectionOrderCombo = new wxComboBox( panel, ID_LOO_SEL_ORDER_COMBOBOX, looSelectionOrderStrings[initialSelOrderIndex], wxDefaultPosition, wxDefaultSize, sizeof(looSelectionOrderStrings)/sizeof(looSelectionOrderStrings[0]), looSelectionOrderStrings, wxCB_READONLY );
looSelectionOrderCombo->Show(false);
// item5->Add( looSelectionOrderCombo, 0, wxALIGN_RIGHT|wxALL, 5 );
// # of independent refinement trials
// wxStaticText *item62 = new wxStaticText( panel, ID_TEXT, wxT("Number of refinement trials:"), wxDefaultPosition, wxDefaultSize, 0 );
// item5->Add( item62, 0, wxALIGN_CENTER_VERTICAL|wxALL, 5 );
hSizer = new wxBoxSizer(wxHORIZONTAL);
nTrialsSpin = new IntegerSpinCtrl(panel,
1, 10, 1, current_genl.nTrials,
wxDefaultPosition, wxSize(80, SPIN_CTRL_HEIGHT), 0,
wxDefaultPosition, wxSize(-1, SPIN_CTRL_HEIGHT));
hSizer->Add(nTrialsSpin->GetTextCtrl(), 0, wxALIGN_RIGHT|wxLEFT|wxTOP|wxBOTTOM, 5);
hSizer->Add(nTrialsSpin->GetSpinButton(), 0, wxALIGN_LEFT|wxRIGHT|wxTOP|wxBOTTOM, 5);
nTrialsSpin->GetTextCtrl()->Show(false);
nTrialsSpin->GetSpinButton()->Show(false);
// item5->Add(hSizer, 0, wxALIGN_RIGHT);
// use entire sequence length, or restricted to aligned footprint
wxStaticText *item9 = new wxStaticText( panel, ID_TEXT, wxT("Refine using full sequence:"), wxDefaultPosition, wxDefaultSize, 0 );
item5->Add( item9, 0, wxALIGN_CENTER_VERTICAL|wxALL, 5 );
// wxStaticText *item10 = new wxStaticText( panel, ID_TEXT, wxT(""), wxDefaultPosition, wxDefaultSize, 0 );
// item5->Add( item10, 0, wxALIGN_CENTRE|wxLEFT|wxTOP|wxBOTTOM, 5 );
fullSeqCheck = new wxCheckBox( panel, ID_FULL_SEQ_CHECKBOX, wxT(""), wxDefaultPosition, wxDefaultSize, 0 );
fullSeqCheck->SetValue(current_loo.fullSequence);
item5->Add( fullSeqCheck, 0, wxALIGN_RIGHT|wxALL, 5 );
// Allow extension/contraction of footprint (N-terminus)
wxStaticText *item30 = new wxStaticText( panel, ID_TEXT, wxT("N-terminal footprint extension:"), wxDefaultPosition, wxDefaultSize, 0 );
item5->Add( item30, 0, wxALIGN_CENTER_VERTICAL|wxALL, 5 );
hSizer = new wxBoxSizer(wxHORIZONTAL);
nExtSpin = new IntegerSpinCtrl(panel,
-1000, 1000, 5, current_loo.nExt,
wxDefaultPosition, wxSize(80, SPIN_CTRL_HEIGHT), 0,
wxDefaultPosition, wxSize(-1, SPIN_CTRL_HEIGHT));
hSizer->Add(nExtSpin->GetTextCtrl(), 0, wxALIGN_RIGHT|wxLEFT|wxTOP|wxBOTTOM, 5);
hSizer->Add(nExtSpin->GetSpinButton(), 0, wxALIGN_LEFT|wxRIGHT|wxTOP|wxBOTTOM, 5);
item5->Add(hSizer, 0, wxALIGN_RIGHT);
// Allow extension/contraction of footprint (C-terminus)
wxStaticText *item33 = new wxStaticText( panel, ID_TEXT, wxT("C-terminal footprint extension:"), wxDefaultPosition, wxDefaultSize, 0 );
item5->Add( item33, 0, wxALIGN_CENTER_VERTICAL|wxALL, 5 );
hSizer = new wxBoxSizer(wxHORIZONTAL);
cExtSpin = new IntegerSpinCtrl(panel,
-1000, 1000, 5, current_loo.cExt,
wxDefaultPosition, wxSize(80, SPIN_CTRL_HEIGHT), 0,
wxDefaultPosition, wxSize(-1, SPIN_CTRL_HEIGHT));
hSizer->Add(cExtSpin->GetTextCtrl(), 0, wxALIGN_RIGHT|wxLEFT|wxTOP|wxBOTTOM, 5);
hSizer->Add(cExtSpin->GetSpinButton(), 0, wxALIGN_LEFT|wxRIGHT|wxTOP|wxBOTTOM, 5);
item5->Add(hSizer, 0, wxALIGN_RIGHT);
// Blank space
wxStaticText *item124 = new wxStaticText( panel, ID_TEXT, wxT(""), wxDefaultPosition, wxDefaultSize, 0 );
item5->Add( item124, 0, wxALIGN_CENTER, 5 );
wxStaticText *item125 = new wxStaticText( panel, ID_TEXT, wxT(""), wxDefaultPosition, wxDefaultSize, 0 );
item5->Add( item125, 0, wxALIGN_CENTER, 5 );
// wxStaticText *item26 = new wxStaticText( panel, ID_TEXT, wxT(""), wxDefaultPosition, wxDefaultSize, 0 );
// item5->Add( item26, 0, wxALIGN_CENTER, 5 );
// Block aligner's loop percentile parameter
wxStaticText *item15 = new wxStaticText( panel, ID_TEXT, wxT("Loop percentile:"), wxDefaultPosition, wxDefaultSize, wxALIGN_CENTRE );
item5->Add( item15, 0, wxALIGN_CENTER_VERTICAL|wxALL, 5 );
hSizer = new wxBoxSizer(wxHORIZONTAL);
loopPercentSpin = new FloatingPointSpinCtrl(panel,
0.0, 100.0, 0.1, current_loo.percentile,
wxDefaultPosition, wxSize(80, SPIN_CTRL_HEIGHT), 0,
wxDefaultPosition, wxSize(-1, SPIN_CTRL_HEIGHT));
hSizer->Add(loopPercentSpin->GetTextCtrl(), 0, wxALIGN_RIGHT|wxLEFT|wxTOP|wxBOTTOM, 5);
hSizer->Add(loopPercentSpin->GetSpinButton(), 0, wxALIGN_LEFT|wxRIGHT|wxTOP|wxBOTTOM, 5);
item5->Add(hSizer, 0, wxALIGN_RIGHT);
// Block aligner's loop extension parameter
wxStaticText *item18 = new wxStaticText( panel, ID_TEXT, wxT("Loop extension:"), wxDefaultPosition, wxDefaultSize, wxALIGN_CENTRE );
item5->Add( item18, 0, wxALIGN_CENTER_VERTICAL|wxALL, 5 );
hSizer = new wxBoxSizer(wxHORIZONTAL);
loopExtensionSpin = new IntegerSpinCtrl(panel,
0, 10000, 5, current_loo.extension,
wxDefaultPosition, wxSize(80, SPIN_CTRL_HEIGHT), 0,
wxDefaultPosition, wxSize(-1, SPIN_CTRL_HEIGHT));
hSizer->Add(loopExtensionSpin->GetTextCtrl(), 0, wxALIGN_RIGHT|wxLEFT|wxTOP|wxBOTTOM, 5);
hSizer->Add(loopExtensionSpin->GetSpinButton(), 0, wxALIGN_LEFT|wxRIGHT|wxTOP|wxBOTTOM, 5);
item5->Add(hSizer, 0, wxALIGN_RIGHT);
// Block aligner's loop cutoff parameter
wxStaticText *item21 = new wxStaticText( panel, ID_TEXT, wxT("Loop cutoff (0=none):"), wxDefaultPosition, wxDefaultSize, wxALIGN_CENTRE );
item5->Add( item21, 0, wxALIGN_CENTER_VERTICAL|wxALL, 5 );
hSizer = new wxBoxSizer(wxHORIZONTAL);
loopCutoffSpin = new IntegerSpinCtrl(panel,
0, 10000, 5, current_loo.cutoff,
wxDefaultPosition, wxSize(80, SPIN_CTRL_HEIGHT), 0,
wxDefaultPosition, wxSize(-1, SPIN_CTRL_HEIGHT));
hSizer->Add(loopCutoffSpin->GetTextCtrl(), 0, wxALIGN_RIGHT|wxLEFT|wxTOP|wxBOTTOM, 5);
hSizer->Add(loopCutoffSpin->GetSpinButton(), 0, wxALIGN_LEFT|wxRIGHT|wxTOP|wxBOTTOM, 5);
item5->Add(hSizer, 0, wxALIGN_RIGHT);
// Seed for RNG to define order of leaving out rows (useful for debugging!!)
// wxStaticText *item27 = new wxStaticText( panel, ID_TEXT, wxT("Random number seed (0=no preference):"), wxDefaultPosition, wxDefaultSize, 0 );
// item5->Add( item27, 0, wxALIGN_CENTER_VERTICAL|wxALL, 5 );
hSizer = new wxBoxSizer(wxHORIZONTAL);
rngSpin = new IntegerSpinCtrl(panel,
0, 1000000000, 3727851, current_loo.seed,
wxDefaultPosition, wxSize(80, SPIN_CTRL_HEIGHT), 0,
wxDefaultPosition, wxSize(-1, SPIN_CTRL_HEIGHT));
hSizer->Add(rngSpin->GetTextCtrl(), 0, wxALIGN_RIGHT|wxLEFT|wxTOP|wxBOTTOM, 5);
hSizer->Add(rngSpin->GetSpinButton(), 0, wxALIGN_LEFT|wxRIGHT|wxTOP|wxBOTTOM, 5);
rngSpin->GetTextCtrl()->Show(false);
rngSpin->GetSpinButton()->Show(false);
// item5->Add(hSizer, 0, wxALIGN_RIGHT);
item3->Add( item5, 0, wxALIGN_CENTER_VERTICAL, 0 );
// ************************************************** //
// Start GUI elements for block extension parameters.
wxStaticBox *item37 = new wxStaticBox( panel, -1, wxT("Block Modification Parameters") );
item37->SetFont( wxFont( 10, wxROMAN, wxNORMAL, wxBOLD ) );
wxStaticBoxSizer *item36 = new wxStaticBoxSizer( item37, wxVERTICAL );
wxFlexGridSizer *item38 = new wxFlexGridSizer( 2, 0, 0 );
item38->AddGrowableCol( 1 );
// Allow block extension?
int initialValue = (current_be.algMethod >= 0 && current_be.algMethod < eGreedyExtend) ? (int) current_be.algMethod : 0;
wxStaticText *item39 = new wxStaticText( panel, ID_TEXT, wxT("Change block model?"), wxDefaultPosition, wxDefaultSize, 0 );
item38->Add( item39, 0, wxALIGN_CENTER_VERTICAL|wxALL, 5 );
esCombo= new wxComboBox( panel, ID_BE_COMBOBOX, wxT(""), wxDefaultPosition, wxDefaultSize, sizeof(blockEditAlgStrings)/sizeof(blockEditAlgStrings[0]), blockEditAlgStrings, wxCB_READONLY );
esCombo->SetValue(blockEditAlgStrings[initialValue]);
item38->Add( esCombo, 0, wxALIGN_RIGHT|wxALL, 5 );
// Expand first?
wxStaticText *item39b = new wxStaticText( panel, ID_TEXT, wxT("Expand first?"), wxDefaultPosition, wxDefaultSize, 0 );
item38->Add( item39b, 0, wxALIGN_CENTER_VERTICAL|wxALL, 5 );
extendFirstCheck = new wxCheckBox( panel, ID_BEXTEND_FIRST_CHECKBOX, wxT(""), wxDefaultPosition, wxDefaultSize, 0 );
extendFirstCheck->SetValue(current_be.extendFirst);
item38->Add( extendFirstCheck, 0, wxALIGN_RIGHT|wxALL, 5 );
// Define a minimum block size (really only relevant for shrinking blocks...
wxStaticText *item42 = new wxStaticText( panel, ID_TEXT, wxT("Minimum block size:"), wxDefaultPosition, wxDefaultSize, 0 );
item38->Add( item42, 0, wxALIGN_CENTER_VERTICAL|wxALL, 5 );
hSizer = new wxBoxSizer(wxHORIZONTAL);
minBlockSizeSpin = new IntegerSpinCtrl(panel,
1, 100, 1, current_be.minBlockSize,
wxDefaultPosition, wxSize(80, SPIN_CTRL_HEIGHT), 0,
wxDefaultPosition, wxSize(-1, SPIN_CTRL_HEIGHT));
hSizer->Add(minBlockSizeSpin->GetTextCtrl(), 0, wxALIGN_RIGHT|wxLEFT|wxTOP|wxBOTTOM, 5);
hSizer->Add(minBlockSizeSpin->GetSpinButton(), 0, wxALIGN_LEFT|wxRIGHT|wxTOP|wxBOTTOM, 5);
item38->Add(hSizer, 0, wxALIGN_RIGHT);
// Block extension/shrinkage threshold 1: column of PSSM median score >= this value
wxStaticText *item45 = new wxStaticText( panel, ID_TEXT, wxT("Median PSSM score threshold:"), wxDefaultPosition, wxDefaultSize, 0 );
item38->Add( item45, 0, wxALIGN_CENTER_VERTICAL|wxALL, 5 );
hSizer = new wxBoxSizer(wxHORIZONTAL);
medianSpin = new IntegerSpinCtrl(panel,
-20, 20, 1, current_be.median,
wxDefaultPosition, wxSize(80, SPIN_CTRL_HEIGHT), 0,
wxDefaultPosition, wxSize(-1, SPIN_CTRL_HEIGHT));
hSizer->Add(medianSpin->GetTextCtrl(), 0, wxALIGN_RIGHT|wxLEFT|wxTOP|wxBOTTOM, 5);
hSizer->Add(medianSpin->GetSpinButton(), 0, wxALIGN_LEFT|wxRIGHT|wxTOP|wxBOTTOM, 5);
item38->Add(hSizer, 0, wxALIGN_RIGHT);
// Block extension/shrinkage threshold 2: % rows w/ PSSM score >= 0 must exceed this value
wxStaticText *item48 = new wxStaticText( panel, ID_TEXT, wxT("Voting percentage (% of rows vote to extend):"), wxDefaultPosition, wxDefaultSize, 0 );
item38->Add( item48, 0, wxALIGN_CENTER_VERTICAL|wxALL, 5 );
hSizer = new wxBoxSizer(wxHORIZONTAL);
rawVoteSpin = new FloatingPointSpinCtrl(panel,
0.0, 100.0, 1.0, 100.0*(1.0 - current_be.negRowsFraction),
wxDefaultPosition, wxSize(80, SPIN_CTRL_HEIGHT), 0,
wxDefaultPosition, wxSize(-1, SPIN_CTRL_HEIGHT));
hSizer->Add(rawVoteSpin->GetTextCtrl(), 0, wxALIGN_RIGHT|wxLEFT|wxTOP|wxBOTTOM, 5);
hSizer->Add(rawVoteSpin->GetSpinButton(), 0, wxALIGN_LEFT|wxRIGHT|wxTOP|wxBOTTOM, 5);
item38->Add(hSizer, 0, wxALIGN_RIGHT);
// Block extension/shrinkage threshold 3: % of weight in column of PSSM median score >= 0 must exceed this value
wxStaticText *item51 = new wxStaticText( panel, ID_TEXT, wxT("Weighted (by PSSM score) voting percentage:"), wxDefaultPosition, wxDefaultSize, 0 );
item38->Add( item51, 0, wxALIGN_CENTER_VERTICAL|wxALL, 5 );
hSizer = new wxBoxSizer(wxHORIZONTAL);
weightedVoteSpin = new FloatingPointSpinCtrl(panel,
0.0, 100.0, 1.0, 100.0*(1.0 - current_be.negScoreFraction),
wxDefaultPosition, wxSize(80, SPIN_CTRL_HEIGHT), 0,
wxDefaultPosition, wxSize(-1, SPIN_CTRL_HEIGHT));
hSizer->Add(weightedVoteSpin->GetTextCtrl(), 0, wxALIGN_RIGHT|wxLEFT|wxTOP|wxBOTTOM, 5);
hSizer->Add(weightedVoteSpin->GetSpinButton(), 0, wxALIGN_LEFT|wxRIGHT|wxTOP|wxBOTTOM, 5);
item38->Add(hSizer, 0, wxALIGN_RIGHT);
item36->Add( item38, 0, wxALIGN_CENTER|wxALL, 5 );
// Enable/disable block-editing controls based on state of 'extendCheck' & 'shrinkCheck'.
wxCommandEvent dummyEvent;
dummyEvent.SetId(ID_BE_COMBOBOX);
OnCombo(dummyEvent);
// Enable/disable loo controls based on state of shift blocks checkbox
dummyEvent.SetId(ID_DO_LOO_CHECKBOX);
OnCheck(dummyEvent);
// Enable/disable specific controls based on selected row selection order
dummyEvent.SetId(ID_LOO_SEL_ORDER_COMBOBOX);
OnLooSelOrder(dummyEvent);
// OK/Cancel buttons
wxBoxSizer *item54 = new wxBoxSizer( wxHORIZONTAL );
wxButton *item55 = new wxButton( panel, wxID_OK, wxT("OK"), wxDefaultPosition, wxDefaultSize, 0 );
item55->SetDefault();
item54->Add( item55, 0, wxALIGN_CENTER|wxALL, 5 );
wxButton *item56 = new wxButton( panel, wxID_CANCEL, wxT("Cancel"), wxDefaultPosition, wxDefaultSize, 0 );
item54->Add( item56, 0, wxALIGN_CENTER|wxALL, 5 );
wxBoxSizer *item103 = new wxBoxSizer( wxHORIZONTAL );
// Place sub-sizers in outermost sizer.
wxBoxSizer *item0 = new wxBoxSizer( wxVERTICAL );
item0->Add( item64, 0, wxALIGN_CENTER|wxALL, 5 );
// item0->Add( item3, 0, wxALIGN_CENTER_VERTICAL|wxALL, 5 );
// item0->Add( item36, 0, wxALIGN_CENTER|wxALL, 5 );
item103->Add( item3, 0, wxALIGN_CENTER_VERTICAL|wxALL, 5 );
item103->Add( item36, 0, wxALIGN_CENTER_HORIZONTAL | wxALIGN_TOP |wxALL, 5 );
item0->Add(item103, 0, wxALIGN_CENTER|wxALL, 2);
item0->Add( item54, 0, wxALIGN_CENTER|wxALL, 5 );
panel->SetAutoLayout(true);
panel->SetSizer(item0);
item0->Fit(this);
item0->Fit(panel);
item0->SetSizeHints(this);
// return item0;
}
