Esempio n. 1
0
/* ----------------------------- MNI Header -----------------------------------
@NAME       :  compute_chamfer
@INPUT/OUTPUT: chamfer
                   The original input volume will be destroyed and replaced
                   with the resulting chamfer distance volume.  The chamfer
                   will contains 0's where the mask was and values > 0.0
                   for all other voxels, where the value is an estimate of
                   the distance to the the nearest voxel of the mask.
@RETURNS    : ERROR if error, OK otherwise
@DESCRIPTION: Uses an idea from georges, who got it from claire, 
              who got it from Borgefors
@GLOBALS    : 
@CALLS      : 
@CREATED    : Nov 2, 1998 Louis
@MODIFIED   : 
---------------------------------------------------------------------------- */
VIO_Status compute_chamfer(VIO_Volume chamfer, VIO_Real max_val)
{

   VIO_Real
      mask_f[3][3][3],
      mask_b[3][3][3],
      zero, min,
      vox_min, vox_max,
      val, val2;
   int
      sizes[VIO_MAX_DIMENSIONS],
      i,j,k,
      ind0,ind1,ind2;
   
   VIO_progress_struct 
      progress;
   
   get_volume_sizes(chamfer, sizes);

   get_volume_voxel_range(chamfer, &vox_min, &vox_max);

   zero = CONVERT_VALUE_TO_VOXEL(chamfer,0.0);
   
   /* init chamfer to be  binary valued with 0.0 on the object,
      and infinity (or vox_max) elsewhere */
   
   if (debug) print ("initing chamfer vol (%d %d %d)\n",sizes[0],sizes[1],sizes[2]);
   for(ind0=0; ind0<sizes[0]; ind0++) {
      for(ind1=0; ind1<sizes[1]; ind1++) {
         for(ind2=0; ind2<sizes[2]; ind2++) {
            
            GET_VOXEL_3D(val, chamfer, ind0, ind1, ind2);
            if (val == zero) {
               SET_VOXEL_3D(chamfer, ind0, ind1, ind2, vox_max ); 
            }            
            else {
               SET_VOXEL_3D(chamfer, ind0, ind1, ind2, vox_min); 
            }
            
         }
      }
   }

   if (debug) print ("building mask\n");

   build_mask(chamfer, mask_f, mask_b);

   set_volume_real_range(chamfer, 0.0, max_val);
   zero = CONVERT_VALUE_TO_VOXEL(chamfer,0.0);

   if (verbose) initialize_progress_report( &progress, TRUE, sizes[0], 
                                           "forward pass");
   
   for(ind0=1; ind0<sizes[0]-1; ind0++) {
      for(ind1=1; ind1<sizes[1]-1; ind1++) {
         for(ind2=1; ind2<sizes[2]-1; ind2++) {

            GET_VALUE_3D(val, chamfer, ind0, ind1, ind2);
            
            if (val != zero) { /* then apply forward mask */

               min = val;

               for(i=-1; i<=+1; i++) {
                  for(j=-1; j<=+1; j++) {
                     for(k=-1; k<=+1; k++) {
                        
                        GET_VALUE_3D(val, chamfer, i+ind0, j+ind1, k+ind2);
                        
                        val2 = val + mask_f[i+1][j+1][k+1];
                        min = MIN (min, val2);
                        
                     }
                  }
               }
                           
               min = convert_value_to_voxel(chamfer, min);

               SET_VOXEL_3D(chamfer, ind0, ind1, ind2, min );              
               
            } /* if val != 0.0 */
            
         } /* ind2 */
      } /* ind1 */
      if (verbose) update_progress_report( &progress, ind0+1 );
   } /* ind0 */
   
   if (verbose) terminate_progress_report( &progress );


   if (verbose) initialize_progress_report( &progress, TRUE, sizes[0], 
                                           "reverse pass");
       
   for(ind0=sizes[0]-2; ind0>=1; ind0--) {
      for(ind1=sizes[1]-2; ind1>=1; ind1--) {
         for(ind2=sizes[2]-2; ind2>=1; ind2--) {
            
            GET_VALUE_3D(val, chamfer, ind0, ind1, ind2);
            
            if (val != zero) { /* then apply backwardmask */
                                
               min = val;

               for(i=-1; i<=1; i++) {
                  for(j=-1; j<=+1; j++) {
                     for(k=-1; k<=+1; k++) {
                        
                        GET_VALUE_3D(val, chamfer, i+ind0, j+ind1, k+ind2);
                        
                        val2 = val + mask_b[i+1][j+1][k+1];
                        min = MIN (min, val2);
                        
                     }
                  }
               }
                           
               min = convert_value_to_voxel(chamfer, min);

               SET_VOXEL_3D(chamfer, ind0, ind1, ind2, min );              
               
            } /* if val != 0.0 */
            
         } /* ind2 */
      } /* ind1 */
      if (verbose) update_progress_report( &progress, ind0+1 );
   } /* ind0 */
   
   if (verbose) terminate_progress_report( &progress );
   
   return (OK);
   
}
Esempio n. 2
0
VIO_Status gradient3D_volume(FILE *ifd, 
                                VIO_Volume data, 
                                int xyzv[VIO_MAX_DIMENSIONS],
                                char *infile,
                                char *outfile, 
                                int ndim,
                                char *history,
                                int curvature_flg)

{ 
  float 
    *fdata,                        /* floating point storage for blurred volume */
    *f_ptr,                        /* pointer to fdata */
    tmp,
    max_val, 
    min_val,
    
    *dat_vector,                /* temp storage of original row, col or slice vect. */
    *dat_vecto2,                /* storage of result of dat_vector*kern                 */
    *kern;                        /* convolution kernel                               */
  int                                
    total_voxels,                
    vector_size_data,                /* original size of row, col or slice vector        */
    array_size_pow2,                /* actual size of vector/kernel data used in FFT    */
                                /* routines - needs to be a power of two            */
    array_size;

  int   
    data_offset;                /* offset required to place original data (size n)  */
                                /*  into array (size m=2^n) so that data is centered*/

  register int 
    slice_limit,
    row,col,slice,                /* counters to access original data                 */
    vindex;                        /* counter to access vector and vecto2              */

  int 
    slice_size,                        /* size of each data step - in bytes                */
    row_size, col_size;
                

  char
    full_outfilename[256];        /* name of output file */

  progress_struct 
    progress;                        /* used to monitor progress of calculations         */

  VIO_Status 
    status;
  
  int
    sizes[3],                        /* number of rows, cols and slices */
    pos[3];                          /* Input order of rows, cols, slices */

  VIO_Real
    steps[3];                        /* size of voxel step from center to center in x,y,z */

  /*---------------------------------------------------------------------------------*/
  /*             start by setting up the raw data.                                   */
  /*---------------------------------------------------------------------------------*/



  get_volume_sizes(data, sizes);          /* rows,cols,slices */
  get_volume_separations(data, steps);
  
  slice_size = sizes[xyzv[VIO_Y]] * sizes[xyzv[VIO_X]];    /* sizeof one slice  */
  col_size   = sizes[xyzv[VIO_Y]];               /* sizeof one column */
  row_size   = sizes[xyzv[VIO_X]];               /* sizeof one row    */
  
  total_voxels = sizes[xyzv[VIO_Y]]*sizes[xyzv[VIO_X]]*sizes[xyzv[VIO_Z]];
  
  ALLOC(fdata, total_voxels);
  f_ptr = fdata;

         /* read in data of input file. */

  set_file_position(ifd,(long)0);
  status = io_binary_data(ifd,READ_FILE, fdata, sizeof(float), total_voxels);
  if (status != OK)
    print_error_and_line_num("problems reading binary data...\n",__FILE__, __LINE__);


  /*--------------------------------------------------------------------------------------*/
  /*                get ready to start up the transformation.                             */
  /*--------------------------------------------------------------------------------------*/
  
  initialize_progress_report( &progress, FALSE, sizes[xyzv[VIO_Z]] + sizes[xyzv[VIO_Y]] + sizes[xyzv[VIO_X]] + 1,
                             "Gradient volume" );


  /* note data is stored by rows (along x), then by cols (along y) then slices (along z) */
  

  /*--------------------------------------------------------------------------------------*/
  /*                start with rows - i.e. the d/dx volume                                */
  /*--------------------------------------------------------------------------------------*/
  
  /*-----------------------------------------------------------------------------*/
  /*             determine   size of data structures needed                      */
  
  vector_size_data = sizes[xyzv[VIO_X]]; 
  
  /*             array_size_pow2 will hold the size of the arrays for FFT convolution,
                 remember that ffts require arrays 2^n in length                          */
  
  array_size_pow2  = next_power_of_two(vector_size_data);
  array_size = 2*array_size_pow2+1;  /* allocate 2*, since each point is a    */
                                     /* complex number for FFT, and the plus 1*/
                                     /* is for the zero offset FFT routine    */

  ALLOC(dat_vector, array_size);
  ALLOC(dat_vecto2, array_size);
  ALLOC(kern      , array_size);
  
  /*    1st calculate kern array for FT of 1st derivitive */
  
  make_kernel_FT(kern,array_size_pow2, ABS(steps[xyzv[VIO_X]]));

  if (curvature_flg)                /* 2nd derivative kernel */
    muli_vects(kern,kern,kern,array_size_pow2);

  /*    calculate offset for original data to be placed in vector            */
  
  data_offset = (array_size_pow2-sizes[xyzv[VIO_X]])/2;
  
  max_val = -FLT_MAX;
  min_val =  FLT_MAX;


  /*    2nd now convolve this kernel with the rows of the dataset            */  
  
  slice_limit = 0;
  switch (ndim) {
  case 1: slice_limit = 0; break;
  case 2: slice_limit = sizes[xyzv[VIO_Z]]; break;
  case 3: slice_limit = sizes[xyzv[VIO_Z]]; break;
  }


  for (slice = 0; slice < slice_limit; slice++) {      /* for each slice */
    
    for (row = 0; row < sizes[xyzv[VIO_Y]]; row++) {           /* for each row   */
      
      f_ptr = fdata + slice*slice_size + row*sizes[xyzv[VIO_X]];
      memset(dat_vector,0,(2*array_size_pow2+1)*sizeof(float));
      
      for (col=0; col< sizes[xyzv[VIO_X]]; col++) {        /* extract the row */
        dat_vector[1 +2*(col+data_offset)  ] = *f_ptr++;
      }
      
      fft1(dat_vector,array_size_pow2,1);
      muli_vects(dat_vecto2,dat_vector,kern,array_size_pow2);
      fft1(dat_vecto2,array_size_pow2,-1);
      
      f_ptr = fdata + slice*slice_size + row*sizes[xyzv[VIO_X]];
      for (col=0; col< sizes[xyzv[VIO_X]]; col++) {        /* put the row back */
        
        vindex = 1 + 2*(col+data_offset);
       *f_ptr = dat_vecto2[vindex]/array_size_pow2;


        if (max_val<*f_ptr) max_val = *f_ptr;
        if (min_val>*f_ptr) min_val = *f_ptr;


        f_ptr++;
      }
      
      
    }
    update_progress_report( &progress, slice+1 );
  }
  
  FREE(dat_vector);
  FREE(dat_vecto2);
  FREE(kern      );
    

  f_ptr = fdata;

  set_volume_real_range(data, min_val, max_val);
  
  
  printf("Making byte volume dx..." );
  for(slice=0; slice<sizes[xyzv[VIO_Z]]; slice++) {
    pos[xyzv[VIO_Z]] = slice;
    for(row=0; row<sizes[xyzv[VIO_Y]]; row++) {
      pos[xyzv[VIO_Y]] = row;
      for(col=0; col<sizes[xyzv[VIO_X]]; col++) {
        pos[xyzv[VIO_X]] = col;
        tmp = CONVERT_VALUE_TO_VOXEL(data, *f_ptr);
        SET_VOXEL_3D( data, pos[0], pos[1], pos[2], tmp);
        f_ptr++;
      }
    }
  }


  if (!curvature_flg)
    sprintf(full_outfilename,"%s_dx.mnc",outfile);
  else
    sprintf(full_outfilename,"%s_dxx.mnc",outfile);

  if (debug)
    print ("dx: min = %f, max = %f\n",min_val, max_val);

  status = output_modified_volume(full_outfilename, NC_UNSPECIFIED, FALSE, 
                                  min_val, max_val, data, infile, history, NULL);

  if (status != OK)
    print_error_and_line_num("problems writing dx gradient data...\n",__FILE__, __LINE__);


  
  /*--------------------------------------------------------------------------------------*/
  /*                 now do cols - i.e. the d/dy volume                                   */
  /*--------------------------------------------------------------------------------------*/
  
  /*-----------------------------------------------------------------------------*/
  /*             determine   size of data structures needed                      */
  

  set_file_position(ifd,0);
  status = io_binary_data(ifd,READ_FILE, fdata, sizeof(float), total_voxels);
  if (status != OK)
    print_error_and_line_num("problems reading binary data...\n",__FILE__, __LINE__);




  
  f_ptr = fdata;

  vector_size_data = sizes[xyzv[VIO_Y]];
  
  /*             array_size_pow2 will hold the size of the arrays for FFT convolution,
                 remember that ffts require arrays 2^n in length                          */
  
  array_size_pow2  = next_power_of_two(vector_size_data);
  array_size = 2*array_size_pow2+1;  /* allocate 2*, since each point is a    */
                                     /* complex number for FFT, and the plus 1*/
                                     /* is for the zero offset FFT routine    */
  
  ALLOC(dat_vector, array_size);
  ALLOC(dat_vecto2, array_size);
  ALLOC(kern      , array_size);
  
  /*    1st calculate kern array for FT of 1st derivitive */
  
  make_kernel_FT(kern,array_size_pow2, ABS(steps[xyzv[VIO_Y]]));
  
  if (curvature_flg)                /* 2nd derivative kernel */
    muli_vects(kern,kern,kern,array_size_pow2);

  /*    calculate offset for original data to be placed in vector            */
  
  data_offset = (array_size_pow2-sizes[xyzv[VIO_Y]])/2;
  
  /*    2nd now convolve this kernel with the rows of the dataset            */
  
  max_val = -FLT_MAX;
  min_val =  FLT_MAX;

  switch (ndim) {
  case 1: slice_limit = 0; break;
  case 2: slice_limit = sizes[xyzv[VIO_Z]]; break;
  case 3: slice_limit = sizes[xyzv[VIO_Z]]; break;
  }

  for (slice = 0; slice < slice_limit; slice++) {      /* for each slice */
    
    for (col = 0; col < sizes[xyzv[VIO_X]]; col++) {           /* for each col   */
      
      /*         f_ptr = fdata + slice*slice_size + row*sizeof(float); */
      
      f_ptr = fdata + slice*slice_size + col;
      
      
      memset(dat_vector,0,(2*array_size_pow2+1)*sizeof(float));
      
      for (row=0; row< sizes[xyzv[VIO_Y]]; row++) {        /* extract the col */
        dat_vector[1 +2*(row+data_offset) ] = *f_ptr;
        f_ptr += row_size;
      }
      
      
      fft1(dat_vector,array_size_pow2,1);
      muli_vects(dat_vecto2,dat_vector,kern,array_size_pow2);
      fft1(dat_vecto2,array_size_pow2,-1);
      
      f_ptr = fdata + slice*slice_size + col;
      for (row=0; row< sizes[xyzv[VIO_Y]]; row++) {        /* put the col back */
        
        vindex = 1 + 2*(row+data_offset);
        
        *f_ptr = dat_vecto2[vindex]/array_size_pow2;
        
        if (max_val<*f_ptr) max_val = *f_ptr;
        if (min_val>*f_ptr) min_val = *f_ptr;

        f_ptr += row_size;
        
        
      }
      
    }
    update_progress_report( &progress, slice+sizes[xyzv[VIO_Z]]+1 );
    
  }
  
  FREE(dat_vector);
  FREE(dat_vecto2);
  FREE(kern      );
  
  f_ptr = fdata;
  
  set_volume_real_range(data, min_val, max_val);


  printf("Making byte volume dy..." );
  for(slice=0; slice<sizes[xyzv[VIO_Z]]; slice++) {
    pos[xyzv[VIO_Z]] = slice;
    for(row=0; row<sizes[xyzv[VIO_Y]]; row++) {
      pos[xyzv[VIO_Y]] = row;
      for(col=0; col<sizes[xyzv[VIO_X]]; col++) {
        pos[xyzv[VIO_X]] = col;
        tmp = CONVERT_VALUE_TO_VOXEL(data, *f_ptr);
        SET_VOXEL_3D( data, pos[0], pos[1], pos[2], tmp);
        f_ptr++;
      }
    }
  }

  if (!curvature_flg)
    sprintf(full_outfilename,"%s_dy.mnc",outfile);
  else
    sprintf(full_outfilename,"%s_dyy.mnc",outfile);


  if (debug)
    print ("dy: min = %f, max = %f\n",min_val, max_val);

  status = output_modified_volume(full_outfilename, NC_UNSPECIFIED, FALSE, 
                                  min_val, max_val, data, infile, history, NULL);
  if (status != OK)
    print_error_and_line_num("problems writing dy gradient data...",__FILE__, __LINE__);
  
  
  /*--------------------------------------------------------------------------------------*/
  /*                 now do slices - i.e. the d/dz volume                                 */
  /*--------------------------------------------------------------------------------------*/
  
  /*-----------------------------------------------------------------------------*/
  /*             determine   size of data structures needed                      */


  set_file_position(ifd,0);
  status = io_binary_data(ifd,READ_FILE, fdata, sizeof(float), total_voxels);
  if (status != OK)
    print_error_and_line_num("problems reading binary data...\n",__FILE__, __LINE__);
  f_ptr = fdata;
  
  vector_size_data = sizes[xyzv[VIO_Z]];

  /*             array_size_pow2 will hold the size of the arrays for FFT convolution,
                 remember that ffts require arrays 2^n in length                          */
  
  array_size_pow2  = next_power_of_two(vector_size_data);
  array_size = 2*array_size_pow2+1;  /* allocate 2*, since each point is a    */
                                     /* complex number for FFT, and the plus 1*/
                                     /* is for the zero offset FFT routine    */
  
  ALLOC(dat_vector, array_size);
  ALLOC(dat_vecto2, array_size);
  ALLOC(kern      , array_size);

  if (ndim==1 || ndim==3) {
    
    /*    1st calculate kern array for FT of 1st derivitive */
    
    make_kernel_FT(kern,array_size_pow2, ABS(steps[xyzv[VIO_Z]]));

    if (curvature_flg)                /* 2nd derivative kernel */
      muli_vects(kern,kern,kern,array_size_pow2);
    
    /*    calculate offset for original data to be placed in vector            */
    
    data_offset = (array_size_pow2-sizes[xyzv[VIO_Z]])/2;
    
    /*    2nd now convolve this kernel with the slices of the dataset            */
    
    max_val = -FLT_MAX;
    min_val =  FLT_MAX;
    
    
    for (col = 0; col < sizes[xyzv[VIO_X]]; col++) {      /* for each column */
      
      for (row = 0; row < sizes[xyzv[VIO_Y]]; row++) {           /* for each row   */
        
        f_ptr = fdata + col*col_size + row;
        
        memset(dat_vector,0,(2*array_size_pow2+1)*sizeof(float));
        
        for (slice=0; slice< sizes[xyzv[VIO_Z]]; slice++) {        /* extract the slice vector */
          dat_vector[1 +2*(slice+data_offset) ] = *f_ptr;
          f_ptr += slice_size;
        }
        
        fft1(dat_vector,array_size_pow2,1);
        muli_vects(dat_vecto2,dat_vector,kern,array_size_pow2);
        fft1(dat_vecto2,array_size_pow2,-1);
        
        f_ptr = fdata + col*col_size + row;
        
        for (slice=0; slice< sizes[xyzv[VIO_Z]]; slice++) {        /* put the vector back */
          
          vindex = 1 + 2*(slice+data_offset);
          
          *f_ptr = dat_vecto2[vindex]/array_size_pow2;
          
          if (max_val<*f_ptr) max_val = *f_ptr;
          if (min_val>*f_ptr) min_val = *f_ptr;
          
          f_ptr += slice_size;
        }
        
        
      }
      update_progress_report( &progress, col + 2*sizes[xyzv[VIO_Z]] + 1 );
      
    }
    
  }  /* if ndim */
  else {
    max_val = 0.00001;
    min_val = 0.00000;
    
    for (col = 0; col < sizes[xyzv[VIO_X]]; col++) {      /* for each column */
      for (row = 0; row < sizes[xyzv[VIO_Y]]; row++) {           /* for each row   */
        *f_ptr = 0.0;
        f_ptr++;
      }
    }
  }
  
  
  FREE(dat_vector);
  FREE(dat_vecto2);
  FREE(kern      );
  
  
/* set up the correct info to copy the data back out in mnc */

  f_ptr = fdata;
  
  set_volume_real_range(data, min_val, max_val);


  printf("Making byte volume dz..." );
  for(slice=0; slice<sizes[xyzv[VIO_Z]]; slice++) {
    pos[xyzv[VIO_Z]] = slice;
    for(row=0; row<sizes[xyzv[VIO_Y]]; row++) {
      pos[xyzv[VIO_Y]] = row;
      for(col=0; col<sizes[xyzv[VIO_X]]; col++) {
        pos[xyzv[VIO_X]] = col;
        tmp = CONVERT_VALUE_TO_VOXEL(data, *f_ptr);
        SET_VOXEL_3D( data, pos[0], pos[1], pos[2], tmp);
        f_ptr++;
      }
    }
  }

  if (!curvature_flg)
    sprintf(full_outfilename,"%s_dz.mnc",outfile);
  else
    sprintf(full_outfilename,"%s_dzz.mnc",outfile);


  if (debug)
    print ("dz: min = %f, max = %f\n",min_val, max_val);

  status = output_modified_volume(full_outfilename, NC_UNSPECIFIED, FALSE, 
                                  min_val, max_val, data, infile, history, NULL);

  if (status != OK)
    print_error_and_line_num("problems writing dz gradient data...",__FILE__, __LINE__);



  terminate_progress_report( &progress );

  FREE(fdata);

  return(status);
  
}
Esempio n. 3
0
void make_zscore_volume(VIO_Volume d1, VIO_Volume m1, 
                               VIO_Real *threshold)
{
  unsigned long
    count;
  int 
    stat_count,
    sizes[VIO_MAX_DIMENSIONS],
    s,r,c;
  VIO_Real
    wx,wy,wz,
    valid_min_dvoxel, valid_max_dvoxel,
    min,max,
    sum, sum2, mean, var, std,
    data_vox,data_val,
    thick[VIO_MAX_DIMENSIONS];

  PointR 
    voxel;

  VIO_Volume 
    vol;

  VIO_progress_struct
    progress;

  /* get default information from data and mask */

  /* build temporary working volume */
 
  vol = copy_volume_definition(d1, NC_UNSPECIFIED, FALSE, 0.0, 0.0);
  set_volume_real_range(vol, MIN_ZRANGE, MAX_ZRANGE);
  get_volume_sizes(d1, sizes);
  get_volume_separations(d1, thick);
  get_volume_voxel_range(d1, &valid_min_dvoxel, &valid_max_dvoxel);

  /* initialize counters and sums */

  count  = 0;
  sum  = 0.0;
  sum2 = 0.0;
  min = 1e38;
  max = -1e38;
  stat_count = 0;

  initialize_progress_report(&progress, FALSE, sizes[0]*sizes[1]*sizes[2] + 1,
                             "Tally stats" );

                                /* do first pass, to get mean and std */
  for(s=0; s<sizes[0]; s++) {
    for(r=0; r<sizes[1]; r++) {
      for(c=0; c<sizes[2]; c++) {

        stat_count++;
        update_progress_report( &progress, stat_count);
        convert_3D_voxel_to_world(d1, (VIO_Real)s, (VIO_Real)r, (VIO_Real)c, &wx, &wy, &wz);

        if (m1 != NULL) {
          convert_3D_world_to_voxel(m1, wx, wy, wz, &Point_x(voxel), &Point_y(voxel), &Point_z(voxel));
        }
        else {
          wx = 0.0; wy = 0.0; wz = 0.0;
        }

        if (point_not_masked(m1, wx,wy,wz)) {
          
          GET_VOXEL_3D( data_vox,  d1 , s, r, c );

          if (data_vox >= valid_min_dvoxel && data_vox <= valid_max_dvoxel) { 

            data_val = CONVERT_VOXEL_TO_VALUE(d1, data_vox);
            
            if (data_val > *threshold) {
              sum  += data_val;
              sum2 += data_val*data_val;
              
              count++;
              
              if (data_val < min)
                min = data_val;
              else
                if (data_val > max)
                  max = data_val;
            }
          }
        }
      }
    }
  }
  terminate_progress_report( &progress );

  stat_count = 0;
  initialize_progress_report(&progress, FALSE, sizes[0]*sizes[1]*sizes[2] + 1,
                             "Zscore convert" );

                                /* calc mean and std */
  mean = sum / (float)count;
  var  = ((float)count*sum2 - sum*sum) / ((float)count*((float)count-1));
  std  = sqrt(var);

  min = 1e38;
  max = -1e38;

                                /* replace the voxel values */
  for(s=0; s<sizes[0]; s++) {
    for(r=0; r<sizes[1]; r++) {
      for(c=0; c<sizes[2]; c++) {
        
        stat_count++;
        update_progress_report( &progress, stat_count);

        GET_VOXEL_3D( data_vox,  d1, s, r, c );
        
        if (data_vox >= valid_min_dvoxel && data_vox <= valid_max_dvoxel) { 
          
          data_val = CONVERT_VOXEL_TO_VALUE(d1, data_vox);
          
          if (data_val > *threshold) {

                                /* instead of   
                                   data_val = CONVERT_VALUE_TO_VOXEL(d1, data_vox);
                                   i will use
                                   data_val = CONVERT_VALUE_TO_VOXEL(d1, vol);

                                   since the values in vol are changed with respect to the
                                   new z-score volume */

            data_val = (data_val - mean) / std;
            if (data_val< MIN_ZRANGE) data_val = MIN_ZRANGE;
            if (data_val> MAX_ZRANGE) data_val = MAX_ZRANGE;

            data_vox = CONVERT_VALUE_TO_VOXEL( vol, data_val);
            

            if (data_val < min) {
              min = data_val;
            }
            else {
              if (data_val > max)
                max = data_val;
            }
          }
          else
            data_vox = -DBL_MAX;   /* should be fill_value! */
          
          SET_VOXEL_3D( d1 , s, r, c, data_vox );
        }
        
      }
    }
  }

  terminate_progress_report( &progress );

  set_volume_real_range(d1, MIN_ZRANGE, MAX_ZRANGE);        /* reset the data volume's range */

  *threshold = (*threshold - mean) / std;

  delete_volume(vol);
  
}
Esempio n. 4
0
void normalize_data_to_match_target(VIO_Volume d1, VIO_Volume m1, VIO_Real thresh1,
                                           VIO_Volume d2, VIO_Volume m2, VIO_Real thresh2,
                                           Arg_Data *globals)
{

  VectorR
    vector_step;

  PointR
    starting_position,
    slice,
    row,
    col,
    pos2,
    voxel;

  double
    tx,ty,tz;
  int
    i,j,k,
    r,c,s;

  VIO_Real
    min_range, max_range,
    data_vox, data_val,
    value1, value2;
  
  VIO_Real
    t1,t2,                        /* temporary threshold values     */
    s1,s2,s3;                   /* to store the sums for f1,f2,f3 */
  float 
    *ratios,
    result;                                /* the result */
  int 
    sizes[VIO_MAX_DIMENSIONS],ratios_size,count1,count2;

  VIO_Volume 
    vol;

  VIO_progress_struct
    progress;

  VIO_Data_types 
    data_type;


  set_feature_value_threshold(d1,d2, 
                              &thresh1, &thresh2,
                              &t1,      &t2);                              

  if (globals->flags.debug) {
    print ("In normalize_data_to_match_target, thresh = %10.3f %10.3f\n",t1,t2) ;
  }

  ratios_size = globals->count[ROW_IND] * globals->count[COL_IND] * globals->count[SLICE_IND];

  ALLOC(ratios, ratios_size);  

  fill_Point( starting_position, globals->start[VIO_X], globals->start[VIO_Y], globals->start[VIO_Z]);

  s1 = s2 = s3 = 0.0;
  count1 = count2 = 0;

  for(s=0; s<=globals->count[SLICE_IND]; s++) {

    SCALE_VECTOR( vector_step, globals->directions[SLICE_IND], s);
    ADD_POINT_VECTOR( slice, starting_position, vector_step );

    for(r=0; r<=globals->count[ROW_IND]; r++) {
      
      SCALE_VECTOR( vector_step, globals->directions[ROW_IND], r);
      ADD_POINT_VECTOR( row, slice, vector_step );
      
      SCALE_POINT( col, row, 1.0); /* init first col position */
      for(c=0; c<=globals->count[COL_IND]; c++) {
        
        convert_3D_world_to_voxel(d1, Point_x(col), Point_y(col), Point_z(col), &tx, &ty, &tz);
        
        fill_Point( voxel, tx, ty, tz ); /* build the voxel POINT */
        
        if (point_not_masked(m1, Point_x(col), Point_y(col), Point_z(col))) {

          value1 = get_value_of_point_in_volume( Point_x(col), Point_y(col), Point_z(col), d1);

          if ( value1 > t1 ) {

            count1++;

            DO_TRANSFORM(pos2, globals->trans_info.transformation, col);
            
            convert_3D_world_to_voxel(d2, Point_x(pos2), Point_y(pos2), Point_z(pos2), &tx, &ty, &tz);
            
            fill_Point( voxel, tx, ty, tz ); /* build the voxel POINT */
        
            if (point_not_masked(m2, Point_x(pos2), Point_y(pos2), Point_z(pos2))) {

              value2 = get_value_of_point_in_volume( Point_x(pos2), Point_y(pos2), Point_z(pos2), d2);

              if ( (value2 > t2)  && 
                   ((value2 < -1e-15) || (value2 > 1e-15)) ) {
                  
                ratios[count2++] = value1 / value2 ;

                s1 += value1*value2;
                s2 += value1*value1;
                s3 += value2*value2;
                  
                
              } /* if voxel in d2 */
            } /* if point in mask volume two */
          } /* if voxel in d1 */
        } /* if point in mask volume one */
        
        ADD_POINT_VECTOR( col, col, globals->directions[COL_IND] );
        
      } /* for c */
    } /* for r */
  } /* for s */
  

  if (count2 > 0) {

    if (globals->flags.debug) (void)print ("Starting qsort of ratios...");


    qs_list (ratios,0,count2);

    if (globals->flags.debug) (void)print ("Done.\n");

    result = ratios[ (int)(count2/2) ];        /* the median value */

    if (globals->flags.debug) (void)print ("Normalization: %7d %7d -> %10.8f\n",count1,count2,result);

    if ( fabs(result) < 1e-15) {
      print_error_and_line_num("Error computing normalization ratio `%f'.",__FILE__, __LINE__, result);
    }
    else {

      data_type = get_volume_data_type(d1);



      
      switch( data_type ) {
      case SIGNED_BYTE: 
      case UNSIGNED_BYTE: 
      case SIGNED_SHORT: 
      case UNSIGNED_SHORT: 
	
	/* build temporary working volume */
	
	vol = copy_volume_definition_no_alloc(d1, NC_UNSPECIFIED, FALSE, 0.0, 0.0);
	get_volume_minimum_maximum_real_value(d1, &min_range, &max_range);
	min_range /= result;
	max_range /= result;
	set_volume_real_range(vol, min_range, max_range);
	get_volume_sizes(d1, sizes);
	
	initialize_progress_report(&progress, FALSE, sizes[0]*sizes[1]*sizes[2] + 1,
				   "Normalizing source data" );
	count1 = 0;
	
	/* reset values in the data volume */
	
	for(i=0; i<sizes[0]; i++)
	  for(j=0; j<sizes[1]; j++) {
	    count1++;
	    update_progress_report( &progress, count1);
	    for(k=0; k<sizes[2]; k++) {
	      GET_VOXEL_3D( data_vox,  d1, i, j, k );
	      data_val = CONVERT_VOXEL_TO_VALUE(d1, data_vox);
	      data_val /= result;
	      data_vox = CONVERT_VALUE_TO_VOXEL( vol, data_val);
	      SET_VOXEL_3D( d1 , i, j, k, data_vox );
	    }
	  }
	
	terminate_progress_report( &progress );
	
	set_volume_real_range(d1, min_range, max_range);
	
	if (globals->flags.debug) (void)print ("After normalization min,max, thresh = %f %f %f\n",
					       min_range, max_range, t1/result);
	
	delete_volume(vol);
	break;
	
      default:			/* then volume should be either float or double */
	
	get_volume_sizes(d1, sizes);
	initialize_progress_report(&progress, FALSE, sizes[0]*sizes[1]*sizes[2] + 1,
				   "Normalizing source data" );
	count1 = 0;
	
	/* nomalize the values in the data volume */
	
	for(i=0; i<sizes[0]; i++)
	  for(j=0; j<sizes[1]; j++) {
	    count1++;
	    update_progress_report( &progress, count1);
	    
	    for(k=0; k<sizes[2]; k++) {	/* it should be possible to directly stream through the voxels, without indexing... */
	      GET_VOXEL_3D( data_vox,  d1, i, j, k );
	      data_val = CONVERT_VOXEL_TO_VALUE(d1, data_vox);
	      data_val /= result;
	      data_vox = CONVERT_VALUE_TO_VOXEL( d1, data_val);
	      SET_VOXEL_3D( d1 , i, j, k, data_vox );
	    }
	  }
	terminate_progress_report( &progress );
      }
    }
    
  }
  FREE(ratios);

  
}
static void resample_the_deformation_field(Arg_Data *globals)
{

  VIO_Volume
    existing_field,
    new_field;
  VIO_Real
    vector_val[3],
    XYZstart[ VIO_MAX_DIMENSIONS ],
    wstart[ VIO_MAX_DIMENSIONS ],
    start[    VIO_MAX_DIMENSIONS ],
    XYZstep[  VIO_MAX_DIMENSIONS ],
    step[     VIO_MAX_DIMENSIONS ],
    step2[    VIO_MAX_DIMENSIONS ],
    s1[       VIO_MAX_DIMENSIONS ],
    voxel[    VIO_MAX_DIMENSIONS ],
    dir[3][3];
  int
    i,
    siz[      VIO_MAX_DIMENSIONS ],
    index[    VIO_MAX_DIMENSIONS ],
    xyzv[     VIO_MAX_DIMENSIONS ],
    XYZcount[ VIO_MAX_DIMENSIONS ],
    count[    VIO_MAX_DIMENSIONS ];
  VIO_General_transform
    *non_lin_part;
  VectorR
    XYZdirections[ VIO_MAX_DIMENSIONS ];
  VIO_Real
    del_x, del_y, del_z, wx, wy,wz;
  VIO_progress_struct
    progress;
  char
    **data_dim_names;


                                /* get the nonlinear part
                                   of the transformation           */

  existing_field = (VIO_Volume)NULL;
  non_lin_part = get_nth_general_transform(globals->trans_info.transformation,
                                           get_n_concated_transforms(
                                               globals->trans_info.transformation)
                                           -1);

  if (get_transform_type( non_lin_part ) == GRID_TRANSFORM){
    existing_field = (VIO_Volume)(non_lin_part->displacement_volume);
  }
  else {
    for(i=0; i<get_n_concated_transforms(globals->trans_info.transformation); i++)
      print ("Transform %d is of type %d\n",i,
             get_transform_type(
                get_nth_general_transform(globals->trans_info.transformation,
                                i) ));

    print_error_and_line_num("Cannot find the deformation field transform to resample",
                             __FILE__, __LINE__);
  }

  /* build a vector volume to store the Grid VIO_Transform */

  new_field = create_volume(4, dim_name_vector_vol, NC_DOUBLE, TRUE, 0.0, 0.0);

  get_volume_XYZV_indices(new_field, xyzv);

  for(i=0; i<VIO_N_DIMENSIONS; i++)
    step2[i] = globals->step[i];
                                /* get new start, count, step and directions,
                                   all returned in X, Y, Z order.          */

  set_up_lattice(existing_field, step2, XYZstart, wstart, XYZcount, XYZstep, XYZdirections);

                                /* reset count and step to be in volume order */
  for(i=0; i<VIO_N_DIMENSIONS; i++) {
    start[      i  ] = wstart[ i ];
    count[ xyzv[i] ] = XYZcount[ i ];
    step[  xyzv[i] ] = XYZstep[  i ];
  }

                                /* add info for the vector dimension */
  count[xyzv[VIO_Z+1]] = 3;
  step[xyzv[VIO_Z+1]] = 0.0;

         /* use the sign of the step returned to set the true step size */
  for(i=0; i<VIO_N_DIMENSIONS; i++) {
    if (step[xyzv[i]]<0)
      step[xyzv[i]] = -1.0 * fabs(globals->step[i]);
    else
      step[xyzv[i]] = fabs(globals->step[i]);
  }

  for(i=0; i<VIO_MAX_DIMENSIONS; i++)  /* set the voxel origin, used in the vol def */
    voxel[i] = 0.0;

  set_volume_sizes(       new_field, count);
  set_volume_separations( new_field, step);

  /*  set_volume_voxel_range( new_field, -MY_MAX_VOX, MY_MAX_VOX);
      set_volume_real_range(  new_field, -1.0*globals->trans_info.max_def_magnitude, globals->trans_info.max_def_magnitude);  - no longer needed, because now using doubles*/

  set_volume_translation( new_field, voxel, start);

  for(i=0; i<VIO_N_DIMENSIONS; i++) {
    dir[VIO_X][i]=XYZdirections[VIO_X].coords[i];
    dir[VIO_Y][i]=XYZdirections[VIO_Y].coords[i];
    dir[VIO_Z][i]=XYZdirections[VIO_Z].coords[i];

  }


  set_volume_direction_cosine(new_field,xyzv[VIO_X],dir[VIO_X]);
  set_volume_direction_cosine(new_field,xyzv[VIO_Y],dir[VIO_Y]);
  set_volume_direction_cosine(new_field,xyzv[VIO_Z],dir[VIO_Z]);


                                /* make sure that the vector dimension
                                   is named! */
  data_dim_names = get_volume_dimension_names(new_field);

  if( strcmp( data_dim_names[ xyzv[VIO_Z+1] ] , MIvector_dimension ) != 0 ) {
    ALLOC((new_field)->dimension_names[xyzv[VIO_Z+1]], \
          strlen(MIvector_dimension  ) + 1 );
    (void) strcpy( (new_field)->dimension_names[xyzv[VIO_Z+1]], MIvector_dimension );
  }

  delete_dimension_names(new_field, data_dim_names);

  if (globals->flags.debug) {
    print ("in resample_deformation_field:\n");
    print ("xyzv[axes] = %d, %d, %d, %d\n",xyzv[VIO_X],xyzv[VIO_Y],xyzv[VIO_Z],xyzv[VIO_Z+1]);

    get_volume_sizes(new_field, siz);
    get_volume_separations(new_field, s1);
    print ("seps: %7.3f %7.3f %7.3f %7.3f %7.3f \n",s1[0],s1[1],s1[2],s1[3],s1[4]);
    print ("size: %7d %7d %7d %7d %7d \n",siz[0],siz[1],siz[2],siz[3],siz[4]);
  }

  alloc_volume_data(new_field);

  if (globals->flags.verbose>0)
    initialize_progress_report( &progress, FALSE, count[xyzv[VIO_X]],
                               "Interpolating new field" );

  /* now resample the values from the input deformation */

  for(i=0; i<VIO_MAX_DIMENSIONS; i++) {
    voxel[i] = 0.0;
    index[i] = 0;
  }

  for(index[xyzv[VIO_X]]=0; index[xyzv[VIO_X]]<count[xyzv[VIO_X]]; index[xyzv[VIO_X]]++) {
    voxel[xyzv[VIO_X]] = (VIO_Real)index[xyzv[VIO_X]];

    for(index[xyzv[VIO_Y]]=0; index[xyzv[VIO_Y]]<count[xyzv[VIO_Y]]; index[xyzv[VIO_Y]]++) {
      voxel[xyzv[VIO_Y]] = (VIO_Real)index[xyzv[VIO_Y]];

      for(index[xyzv[VIO_Z]]=0; index[xyzv[VIO_Z]]<count[xyzv[VIO_Z]]; index[xyzv[VIO_Z]]++) {
        voxel[xyzv[VIO_Z]] = (VIO_Real)index[xyzv[VIO_Z]];

        convert_voxel_to_world(new_field, voxel, &wx,&wy,&wz);


           grid_transform_point(non_lin_part, wx, wy, wz,
                             &del_x, &del_y, &del_z);



                                /* get just the deformation part */
        del_x = del_x - wx;
        del_y = del_y - wy;
        del_z = del_z - wz;


/*        del_x = del_y = del_z = 0.0;
*/
        vector_val[0] = CONVERT_VALUE_TO_VOXEL(new_field, del_x);
        vector_val[1] = CONVERT_VALUE_TO_VOXEL(new_field, del_y);
        vector_val[2] = CONVERT_VALUE_TO_VOXEL(new_field, del_z);

        for(index[xyzv[VIO_Z+1]]=0; index[xyzv[VIO_Z+1]]<3; index[xyzv[VIO_Z+1]]++) {
          SET_VOXEL(new_field, \
                    index[0], index[1], index[2], index[3], index[4], \
                    vector_val[ index[ xyzv[ VIO_Z+1] ] ]);
        }


      }
    }
    if (globals->flags.verbose>0)
      update_progress_report( &progress,index[xyzv[VIO_X]]+1);
  }
  if (globals->flags.verbose>0)
    terminate_progress_report( &progress );

                 /* delete and free up old data */
  delete_volume(non_lin_part->displacement_volume);
               /* set new volumes into transform */
  non_lin_part->displacement_volume = new_field;

}