static void destroyPaths() { PassageMarkerI marker; while (slowPath != NULL_IDX) { marker = slowPath; slowPath = getNextInSequence(marker); destroyPassageMarker(marker); } while (fastPath != NULL_IDX) { marker = fastPath; fastPath = getNextInSequence(marker); destroyPassageMarker(marker); } }
static void trimLongReadTips() { IDnum index; Node *node; PassageMarkerI marker, next; velvetLog("Trimming read tips\n"); for (index = 1; index <= nodeCount(graph); index++) { node = getNodeInGraph(graph, index); if (getUniqueness(node)) continue; for (marker = getMarker(node); marker != NULL_IDX; marker = next) { next = getNextInNode(marker); if (!isInitial(marker) && !isTerminal(marker)) continue; if (isTerminal(marker)) marker = getTwinMarker(marker); while (!getUniqueness(getNode(marker))) { if (next != NULL_IDX && (marker == next || marker == getTwinMarker(next))) next = getNextInNode(next); if (getNextInSequence(marker) != NULL_IDX) { marker = getNextInSequence(marker); destroyPassageMarker (getPreviousInSequence (marker)); } else { destroyPassageMarker(marker); break; } } } } }
static void destroyPaths() { PassageMarker *marker; while (slowPath != NULL) { marker = slowPath; getNodeTime(getNode(marker)); getNodeTime(getTwinNode(getNode(marker))); slowPath = getNextInSequence(marker); destroyPassageMarker(marker); } while (fastPath != NULL) { marker = fastPath; getNodeTime(getNode(marker)); getNodeTime(getTwinNode(getNode(marker))); fastPath = getNextInSequence(marker); destroyPassageMarker(marker); } }
static void updateMembers(Node * bypass, Node * nextNode) { PassageMarkerI marker, next, tmp; Coordinate nextLength = getNodeLength(nextNode); // Update marker + arc info for (marker = getMarker(bypass); marker != NULL_IDX; marker = tmp) { tmp = getNextInNode(marker); if (!isTerminal(marker) && getNode(getNextInSequence(marker)) == nextNode) { // Marker steps right into target next = getNextInSequence(marker); disconnectNextPassageMarker(marker, graph); destroyPassageMarker(next); } else if (getUniqueness(nextNode) && goesToNode(marker, nextNode)) { // Marker goes indirectly to target while (getNode(getNextInSequence(marker)) != nextNode) { next = getNextInSequence(marker); disconnectNextPassageMarker(marker, graph); destroyPassageMarker(next); } next = getNextInSequence(marker); disconnectNextPassageMarker(marker, graph); destroyPassageMarker(next); } else if (!isTerminal(marker) && getFinishOffset(marker) == 0) { // Marker goes somewhere else than to target next = getNextInSequence(marker); incrementFinishOffset(marker, nextLength); } else { // Marker goes nowhere incrementFinishOffset(marker, nextLength); } } }
static void reconnectPassageMarker(PassageMarkerI marker, Node * node, PassageMarkerI * ptr) { PassageMarkerI current; PassageMarkerI next = getNextInSequence(marker); PassageMarkerI tmpMarker; for (current = marker; getNode(current) != node; current = getPreviousInSequence(current)); setPreviousInSequence(current, next); concatenatePassageMarkers(current, marker); // Removing node and all intermediaries while (marker != current) { tmpMarker = getPreviousInSequence(marker); if (*ptr == marker || *ptr == getTwinMarker(marker)) *ptr = getNextInNode(*ptr); setNextInSequence(marker, NULL_IDX); setPreviousInSequence(NULL_IDX, marker); destroyPassageMarker(marker); marker = tmpMarker; } }
static Node *bypass() { Node *bypass = getNode(path); Node *next = NULL; Arc *arc; PassageMarkerI nextMarker; // Remove unwanted arcs while (getArc(bypass) != NULL) destroyArc(getArc(bypass), graph); // Update extensive variables (length + descriptors + passage markers) while (!isTerminal(path)) { nextMarker = getNextInSequence(path); next = getNode(nextMarker); while (next == bypass) { disconnectNextPassageMarker(path, graph); destroyPassageMarker(nextMarker); nextMarker = getNextInSequence(path); next = getNode(nextMarker); } if (next == NULL) return bypass; // Overall node update if (!getUniqueness(next)) { adjustShortReads(bypass, getNextInSequence(path)); appendSequence(bypass, sequences, getNextInSequence(path), graph); } else { concatenateReadStarts(bypass, next, graph); #ifndef SINGLE_COV_CAT Category cat; for (cat = 0; cat < CATEGORIES; cat++) { // Update virtual coverage incrementVirtualCoverage(bypass, cat, getVirtualCoverage(next, cat)); // Update original virtual coverage incrementOriginalVirtualCoverage(bypass, cat, getOriginalVirtualCoverage(next, cat)); } #else incrementVirtualCoverage(bypass, getVirtualCoverage(next)); #endif appendDescriptors(bypass, next); } // Members updateMembers(bypass, next); // Termination if (isTerminal(path) || getUniqueness(next)) break; } // Remove unique groupies from arrival admitGroupies(next, bypass); // Copy destination arcs for (arc = getArc(next); arc != NULL; arc = getNextArc(arc)) { if (getDestination(arc) == next) continue; else if (getDestination(arc) == getTwinNode(next)) createAnalogousArc(bypass, getTwinNode(bypass), arc, graph); else createAnalogousArc(bypass, getDestination(arc), arc, graph); } destroyNode(next, graph); return bypass; }