Esempio n. 1
0
static int32
hmm_vit_eval_3st_lr_mpx(hmm_t * hmm)
{
    uint8 const *tp = hmm->ctx->tp[hmm->tmatid][0];
    int16 const *senscore = hmm->ctx->senscore;
    uint16 * const *sseq = hmm->ctx->sseq;
    uint16 *ssid = hmm->senid;
    int32 bestScore;
    int32 s3, s2, s1, s0, t2, t1, t0;

    /* Don't propagate WORST_SCORE */
    t2 = INT_MIN; /* Not used unless skipstate is true */
    if (ssid[2] == BAD_SSID)
        s2 = t1 = WORST_SCORE;
    else {
        s2 = hmm_score(hmm, 2) + mpx_senscr(2);
        t1 = s2 + hmm_tprob_3st(2, 3);
    }
    if (ssid[1] == BAD_SSID)
        s1 = t2 = WORST_SCORE;
    else {
        s1 = hmm_score(hmm, 1) + mpx_senscr(1);
        if (hmm_tprob_3st(1,3) BETTER_THAN TMAT_WORST_SCORE)
            t2 = s1 + hmm_tprob_3st(1, 3);
    }
    if (t1 BETTER_THAN t2) {
        s3 = t1;
        hmm_out_history(hmm) = hmm_history(hmm, 2);
    }
    else {
        s3 = t2;
        hmm_out_history(hmm) = hmm_history(hmm, 1);
    }
    if (s3 WORSE_THAN WORST_SCORE) s3 = WORST_SCORE;
    hmm_out_score(hmm) = s3;
    bestScore = s3;

    /* State 0 is always active */
    s0 = hmm_in_score(hmm) + mpx_senscr(0);

    /* Don't propagate WORST_SCORE */
    t0 = t1 = WORST_SCORE;
    if (s2 != WORST_SCORE)
        t0 = s2 + hmm_tprob_3st(2, 2);
    if (s1 != WORST_SCORE)
        t1 = s1 + hmm_tprob_3st(1, 2);
    if (hmm_tprob_3st(0,2) BETTER_THAN TMAT_WORST_SCORE)
        t2 = s0 + hmm_tprob_3st(0, 2);
    if (t0 BETTER_THAN t1) {
        if (t2 BETTER_THAN t0) {
            s2 = t2;
            hmm_history(hmm, 2) = hmm_in_history(hmm);
            ssid[2] = ssid[0];
        }
        else
            s2 = t0;
    }
    else {
        if (t2 BETTER_THAN t1) {
            s2 = t2;
            hmm_history(hmm, 2) = hmm_in_history(hmm);
            ssid[2] = ssid[0];
        }
        else {
            s2 = t1;
            hmm_history(hmm, 2) = hmm_history(hmm, 1);
            ssid[2] = ssid[1];
        }
    }
    if (s2 WORSE_THAN WORST_SCORE) s2 = WORST_SCORE;
    if (s2 BETTER_THAN bestScore) bestScore = s2;
    hmm_score(hmm, 2) = s2;

    /* Don't propagate WORST_SCORE */
    t0 = WORST_SCORE;
    if (s1 != WORST_SCORE)
        t0 = s1 + hmm_tprob_3st(1, 1);
    t1 = s0 + hmm_tprob_3st(0, 1);
    if (t0 BETTER_THAN t1) {
        s1 = t0;
    }
    else {
        s1 = t1;
        hmm_history(hmm, 1) = hmm_in_history(hmm);
        ssid[1] = ssid[0];
    }
    if (s1 WORSE_THAN WORST_SCORE) s1 = WORST_SCORE;
    if (s1 BETTER_THAN bestScore) bestScore = s1;
    hmm_score(hmm, 1) = s1;

    /* State 0 is always active */
    s0 += hmm_tprob_3st(0, 0);
    if (s0 WORSE_THAN WORST_SCORE) s0 = WORST_SCORE;
    if (s0 BETTER_THAN bestScore) bestScore = s0;
    hmm_in_score(hmm) = s0;

    hmm_bestscore(hmm) = bestScore;
    return bestScore;
}
Esempio n. 2
0
static int32
hmm_vit_eval_3st_lr_mpx(hmm_t * hmm)
{
    const int32 *tp = hmm->ctx->tp[hmm->tmatid][0];
    const int32 *senscore = hmm->ctx->senscore;
    const s3senid_t **sseq = hmm->ctx->sseq;
    int32 *ssid = hmm->s.mpx_ssid;
    int32 bestScore;
    int32 s3, s2, s1, s0, t2, t1, t0;

    /* Don't propagate WORST_SCORE */
    t2 = INT_MIN; /* Not used unless skipstate is true */
    if (ssid[2] == -1)
        s2 = t1 = WORST_SCORE;
    else {
        s2 = hmm_score(hmm, 2) + mpx_senscr(2);
        if (s2 < WORST_SCORE) s2 = WORST_SCORE;
        t1 = s2 + hmm_tprob_3st(2, 3);
    }
    if (ssid[1] == -1)
        s1 = WORST_SCORE;
    else {
        s1 = hmm_score(hmm, 1) + mpx_senscr(1);
        if (s1 < WORST_SCORE) s1 = WORST_SCORE;
        t2 = s1 + hmm_tprob_3st(1, 3);
    }
    if (t1 > t2) {
        s3 = t1;
        hmm_out_history(hmm) = hmm_history(hmm, 2);
    }
    else {
        s3 = t2;
        hmm_out_history(hmm) = hmm_history(hmm, 1);
    }
    if (s3 < WORST_SCORE) s3 = WORST_SCORE;
    hmm_out_score(hmm) = s3;
    bestScore = s3;

    /* State 0 is always active */
    s0 = hmm_in_score(hmm) + mpx_senscr(0);
    if (s0 < WORST_SCORE) s0 = WORST_SCORE;

    /* Don't propagate WORST_SCORE */
    t0 = t1 = WORST_SCORE;
    if (s2 != WORST_SCORE)
        t0 = s2 + hmm_tprob_3st(2, 2);
    if (s1 != WORST_SCORE)
        t1 = s1 + hmm_tprob_3st(1, 2);
    if (hmm_tprob_3st(0,2) > WORST_SCORE)
        t2 = s0 + hmm_tprob_3st(0, 2);
    if (t0 > t1) {
        if (t2 > t0) {
            s2 = t2;
            hmm_history(hmm, 2) = hmm_in_history(hmm);
            ssid[2] = ssid[0];
        }
        else
            s2 = t0;
    }
    else {
        if (t2 > t1) {
            s2 = t2;
            hmm_history(hmm, 2) = hmm_in_history(hmm);
            ssid[2] = ssid[0];
        }
        else {
            s2 = t1;
            hmm_history(hmm, 2) = hmm_history(hmm, 1);
            ssid[2] = ssid[1];
        }
    }
    if (s2 < WORST_SCORE) s2 = WORST_SCORE;
    if (s2 > bestScore) bestScore = s2;
    hmm_score(hmm, 2) = s2;

    /* Don't propagate WORST_SCORE */
    t0 = WORST_SCORE;
    if (s1 != WORST_SCORE)
        t0 = s1 + hmm_tprob_3st(1, 1);
    t1 = s0 + hmm_tprob_3st(0, 1);
    if (t0 > t1) {
        s1 = t0;
    }
    else {
        s1 = t1;
        hmm_history(hmm, 1) = hmm_in_history(hmm);
        ssid[1] = ssid[0];
    }
    if (s1 < WORST_SCORE) s1 = WORST_SCORE;
    if (s1 > bestScore) bestScore = s1;
    hmm_score(hmm, 1) = s1;

    /* State 0 is always active */
    s0 += hmm_tprob_3st(0, 0);
    if (s0 < WORST_SCORE) s0 = WORST_SCORE;
    if (s0 > bestScore) bestScore = s0;
    hmm_in_score(hmm) = s0;

    hmm_bestscore(hmm) = bestScore;
    return bestScore;
}
Esempio n. 3
0
static int32
hmm_vit_eval_3st_lr(hmm_t * hmm)
{
    int16 const *senscore = hmm->ctx->senscore;
    uint8 const *tp = hmm->ctx->tp[hmm->tmatid][0];
    uint16 const *sseq = hmm->senid;
    int32 s3, s2, s1, s0, t2, t1, t0, bestScore;

    s2 = hmm_score(hmm, 2) + nonmpx_senscr(2);
    s1 = hmm_score(hmm, 1) + nonmpx_senscr(1);
    s0 = hmm_in_score(hmm) + nonmpx_senscr(0);

    /* It was the best of scores, it was the worst of scores. */
    bestScore = WORST_SCORE;
    t2 = INT_MIN; /* Not used unless skipstate is true */

    /* Transitions into non-emitting state 3 */
    if (s1 BETTER_THAN WORST_SCORE) {
        t1 = s2 + hmm_tprob_3st(2, 3);
        if (hmm_tprob_3st(1,3) BETTER_THAN TMAT_WORST_SCORE)
            t2 = s1 + hmm_tprob_3st(1, 3);
        if (t1 BETTER_THAN t2) {
            s3 = t1;
            hmm_out_history(hmm)  = hmm_history(hmm, 2);
        } else {
            s3 = t2;
            hmm_out_history(hmm)  = hmm_history(hmm, 1);
        }
        if (s3 WORSE_THAN WORST_SCORE) s3 = WORST_SCORE;
        hmm_out_score(hmm) = s3;
        bestScore = s3;
    }

    /* All transitions into state 2 (state 0 is always active) */
    t0 = s2 + hmm_tprob_3st(2, 2);
    t1 = s1 + hmm_tprob_3st(1, 2);
    if (hmm_tprob_3st(0, 2) BETTER_THAN TMAT_WORST_SCORE)
        t2 = s0 + hmm_tprob_3st(0, 2);
    if (t0 BETTER_THAN t1) {
        if (t2 BETTER_THAN t0) {
            s2 = t2;
            hmm_history(hmm, 2)  = hmm_in_history(hmm);
        } else
            s2 = t0;
    } else {
        if (t2 BETTER_THAN t1) {
            s2 = t2;
            hmm_history(hmm, 2)  = hmm_in_history(hmm);
        } else {
            s2 = t1;
            hmm_history(hmm, 2)  = hmm_history(hmm, 1);
        }
    }
    if (s2 WORSE_THAN WORST_SCORE) s2 = WORST_SCORE;
    if (s2 BETTER_THAN bestScore) bestScore = s2;
    hmm_score(hmm, 2) = s2;

    /* All transitions into state 1 */
    t0 = s1 + hmm_tprob_3st(1, 1);
    t1 = s0 + hmm_tprob_3st(0, 1);
    if (t0 BETTER_THAN t1) {
        s1 = t0;
    } else {
        s1 = t1;
        hmm_history(hmm, 1)  = hmm_in_history(hmm);
    }
    if (s1 WORSE_THAN WORST_SCORE) s1 = WORST_SCORE;
    if (s1 BETTER_THAN bestScore) bestScore = s1;
    hmm_score(hmm, 1) = s1;

    /* All transitions into state 0 */
    s0 = s0 + hmm_tprob_3st(0, 0);
    if (s0 WORSE_THAN WORST_SCORE) s0 = WORST_SCORE;
    if (s0 BETTER_THAN bestScore) bestScore = s0;
    hmm_in_score(hmm) = s0;

    hmm_bestscore(hmm) = bestScore;
    return bestScore;
}
Esempio n. 4
0
static int32
hmm_vit_eval_3st_lr(hmm_t * hmm)
{
    const int32 *senscore = hmm->ctx->senscore;
    const int32 *tp = hmm->ctx->tp[hmm->tmatid][0];
    const s3senid_t *sseq = hmm->ctx->sseq[hmm_ssid(hmm, 0)];
    int32 s3, s2, s1, s0, t2, t1, t0, bestScore;

    s2 = hmm_score(hmm, 2) + nonmpx_senscr(2);
    s1 = hmm_score(hmm, 1) + nonmpx_senscr(1);
    s0 = hmm_in_score(hmm) + nonmpx_senscr(0);

    /* It was the best of scores, it was the worst of scores. */
    t0 = t1 = bestScore = WORST_SCORE;
    t2 = INT_MIN; /* Not used unless skipstate is true */

    /* Transitions into non-emitting state 3 */
    if (s2 > WORST_SCORE) {
        t1 = s2 + hmm_tprob_3st(2, 3);
        t0 = s2 + hmm_tprob_3st(2, 2);
    }
    if (s1 > WORST_SCORE && hmm_tprob_3st(1,3) > WORST_SCORE)
        t2 = s1 + hmm_tprob_3st(1, 3);
    if (t1 > t2) {
        s3 = t1;
        hmm_out_history(hmm)  = hmm_history(hmm, 2);
    } else {
        s3 = t2;
        hmm_out_history(hmm)  = hmm_history(hmm, 1);
    }
    if (s3 < WORST_SCORE) s3 = WORST_SCORE;
    hmm_out_score(hmm) = s3;
    bestScore = s3;

    /* All transitions into state 2 (state 0 is always active) */
    t1 = t2 = WORST_SCORE;
    if (s1 > WORST_SCORE)
        t1 = s1 + hmm_tprob_3st(1, 2);
    if (hmm_tprob_3st(0, 2) > WORST_SCORE)
        t2 = s0 + hmm_tprob_3st(0, 2);
    if (t0 > t1) {
        if (t2 > t0) {
            s2 = t2;
            hmm_history(hmm, 2)  = hmm_in_history(hmm);
        } else
            s2 = t0;
    } else {
        if (t2 > t1) {
            s2 = t2;
            hmm_history(hmm, 2)  = hmm_in_history(hmm);
        } else {
            s2 = t1;
            hmm_history(hmm, 2)  = hmm_history(hmm, 1);
        }
    }
    if (s2 < WORST_SCORE) s2 = WORST_SCORE;
    if (s2 > bestScore) bestScore = s2;
    hmm_score(hmm, 2) = s2;

    /* All transitions into state 1 */
    t0 = t1 = WORST_SCORE;
    if (s1 > WORST_SCORE)
        t0 = s1 + hmm_tprob_3st(1, 1);
    if (s0 > WORST_SCORE)
        t1 = s0 + hmm_tprob_3st(0, 1);
    if (t0 > t1) {
        s1 = t0;
    } else {
        s1 = t1;
        hmm_history(hmm, 1)  = hmm_in_history(hmm);
    }
    if (s1 < WORST_SCORE) s1 = WORST_SCORE;
    if (s1 > bestScore) bestScore = s1;
    hmm_score(hmm, 1) = s1;

    /* All transitions into state 0 */
    s0 = s0 + hmm_tprob_3st(0, 0);
    if (s0 < WORST_SCORE) s0 = WORST_SCORE;
    if (s0 > bestScore) bestScore = s0;
    hmm_in_score(hmm) = s0;

    hmm_bestscore(hmm) = bestScore;
    return bestScore;
}