static int
mrisFindMiddleOfGray(MRI_SURFACE *mris) {
int vno ;
VERTEX *v ;
float nx, ny, nz, thickness ;
MRISaverageCurvatures(mris, 3) ;
MRISsaveVertexPositions(mris, TMP_VERTICES) ;
MRISrestoreVertexPositions(mris, ORIGINAL_VERTICES) ;
MRIScomputeMetricProperties(mris); /* compute orig surface normals */
for (vno = 0 ; vno < mris->nvertices ; vno++) {
v = &mris->vertices[vno] ;
if (v->ripflag)
continue ;
nx = v->nx ;
ny = v->ny ;
nz = v->nz ;
thickness = 0.5 * v->curv ;
v->origx = v->origx + thickness * nx ;
v->origy = v->origy + thickness * ny ;
v->origz = v->origz + thickness * nz ;
}
MRISrestoreVertexPositions(mris, TMP_VERTICES) ;
MRIScomputeMetricProperties(mris);
return(NO_ERROR) ;
}
static int
extract_thickness_at_best_scale(MRI_SURFACE *mris, float **c1_avg_thickness,
float *vbest_avgs, float **c1_thickness,
int num, int nvectors) {
int i, max_avgs, avgs, n ;
for (max_avgs = i = 0 ; i < num ; i++)
if (nint(vbest_avgs[i]) >= max_avgs)
max_avgs = nint(vbest_avgs[i]) ;
for (avgs = 0 ; avgs <= max_avgs ; avgs++) {
for (n = 0 ; n < nvectors ; n++) {
cvector_extract_best_avg(vbest_avgs, c1_thickness[n],
c1_avg_thickness[n], avgs-1, num) ;
MRISimportCurvatureVector(mris, c1_thickness[n]) ;
MRISaverageCurvatures(mris, 1) ;
MRISextractCurvatureVector(mris, c1_thickness[n]) ;
}
}
return(NO_ERROR) ;
}
int
main(int argc, char *argv[])
{
char **av, *in_fname,fname[STRLEN],hemi[10], path[STRLEN],
name[STRLEN],*cp ;
int ac, nargs, nhandles ;
MRI_SURFACE *mris ;
double ici, fi, var ;
/* rkt: check for and handle version tag */
nargs = handle_version_option
(argc, argv,
"$Id: mris_curvature.c,v 1.31 2011/03/02 00:04:30 nicks Exp $",
"$Name: stable5 $");
if (nargs && argc - nargs == 1)
{
exit (0);
}
argc -= nargs;
Progname = argv[0] ;
ErrorInit(NULL, NULL, NULL) ;
DiagInit(NULL, NULL, NULL) ;
ac = argc ;
av = argv ;
for ( ; argc > 1 && ISOPTION(*argv[1]) ; argc--, argv++)
{
nargs = get_option(argc, argv) ;
argc -= nargs ;
argv += nargs ;
}
if (argc < 2)
{
usage_exit() ;
}
in_fname = argv[1] ;
FileNamePath(in_fname, path) ;
FileNameOnly(in_fname, name) ;
cp = strchr(name, '.') ;
if (!cp)
ErrorExit(ERROR_BADPARM, "%s: could not scan hemisphere from '%s'",
Progname, fname) ;
strncpy(hemi, cp-2, 2) ;
hemi[2] = 0 ;
if (patch_flag) /* read the orig surface, then the patch file */
{
sprintf(fname, "%s/%s.orig", path, hemi) ;
mris = MRISfastRead(fname) ;
if (!mris)
ErrorExit(ERROR_NOFILE, "%s: could not read surface file %s",
Progname, in_fname) ;
if (Gdiag & DIAG_SHOW)
{
fprintf(stderr, "reading patch file %s...\n", in_fname) ;
}
if (MRISreadPatch(mris, in_fname) != NO_ERROR)
ErrorExit(ERROR_NOFILE, "%s: could not read patch file %s",
Progname, in_fname) ;
}
else /* just read the surface normally */
{
mris = MRISread(in_fname) ;
if (!mris)
ErrorExit(ERROR_NOFILE, "%s: could not read surface file %s",
Progname, in_fname) ;
}
MRISsetNeighborhoodSize(mris, nbrs) ;
if (nbhd_size > 0)
{
MRISsampleAtEachDistance(mris, nbhd_size, nbrs_per_distance) ;
}
if (max_mm > 0)
{
float ratio ;
MRISstoreMetricProperties(mris) ;
if (MRISreadCanonicalCoordinates(mris, "sphere") != NO_ERROR)
{
ErrorExit(ERROR_NOFILE,
"%s: could not read canonical coordinates from ?h.sphere",
Progname);
}
MRISsaveVertexPositions(mris, ORIGINAL_VERTICES) ;
MRISrestoreVertexPositions(mris, CANONICAL_VERTICES) ;
MRIScomputeMetricProperties(mris) ;
ratio = mris->orig_area / M_PI * mris->radius * mris->radius * 4.0 ;
ratio = mris->orig_area / mris->total_area ;
MRISscaleBrain(mris, mris, sqrt(ratio)) ;
MRISsaveVertexPositions(mris, CANONICAL_VERTICES) ;
MRISrestoreVertexPositions(mris, ORIGINAL_VERTICES) ;
MRIScomputeMetricProperties(mris) ;
MRIScomputeNeighbors(mris, max_mm) ;
}
if (param_file)
{
MRI_SP *mrisp ;
mrisp = MRISPread(param_file) ;
if (normalize_param)
{
MRISnormalizeFromParameterization(mrisp, mris, param_no) ;
}
else
{
MRISfromParameterization(mrisp, mris, param_no) ;
}
MRISPfree(&mrisp) ;
if (normalize)
{
MRISnormalizeCurvature(mris,which_norm) ;
}
sprintf(fname, "%s/%s%s.param", path,name,suffix) ;
fprintf(stderr, "writing parameterized curvature to %s...", fname) ;
MRISwriteCurvature(mris, fname) ;
fprintf(stderr, "done.\n") ;
}
else
{
MRIScomputeSecondFundamentalFormThresholded(mris, cthresh) ;
nhandles = nint(1.0 - mris->Ktotal / (4.0*M_PI)) ;
fprintf(stderr, "total integrated curvature = %2.3f*4pi (%2.3f) --> "
"%d handles\n", (float)(mris->Ktotal/(4.0f*M_PI)),
(float)mris->Ktotal, nhandles) ;
#if 0
fprintf(stderr, "0: k1 = %2.3f, k2 = %2.3f, H = %2.3f, K = %2.3f\n",
mris->vertices[0].k1, mris->vertices[0].k2,
mris->vertices[0].H, mris->vertices[0].K) ;
fprintf(stderr, "0: vnum = %d, v2num = %d, total=%d, area=%2.3f\n",
mris->vertices[0].vnum, mris->vertices[0].v2num,
mris->vertices[0].vtotal,mris->vertices[0].area) ;
#endif
MRIScomputeCurvatureIndices(mris, &ici, &fi);
var = MRIStotalVariation(mris) ;
fprintf(stderr,"ICI = %2.1f, FI = %2.1f, variation=%2.3f\n", ici, fi, var);
if (diff_flag)
{
MRISuseCurvatureDifference(mris) ;
MRISaverageCurvatures(mris, navgs) ;
sprintf(fname, "%s/%s%s.diff", path,name,suffix) ;
fprintf(stderr, "writing curvature difference to %s...", fname) ;
MRISwriteCurvature(mris, fname) ;
fprintf(stderr, "done.\n") ;
}
if (ratio_flag)
{
MRISuseCurvatureRatio(mris) ;
MRISaverageCurvatures(mris, navgs) ;
if (normalize)
{
MRISnormalizeCurvature(mris,which_norm) ;
}
sprintf(fname, "%s/%s%s.ratio", path,name,suffix) ;
fprintf(stderr, "writing curvature ratio to %s...", fname) ;
MRISwriteCurvature(mris, fname) ;
fprintf(stderr, "done.\n") ;
}
if (contrast_flag)
{
MRISuseCurvatureContrast(mris) ;
MRISaverageCurvatures(mris, navgs) ;
if (normalize)
{
MRISnormalizeCurvature(mris,which_norm) ;
}
sprintf(fname, "%s/%s%s.contrast", path,name,suffix) ;
fprintf(stderr, "writing curvature contrast to %s...", fname) ;
MRISwriteCurvature(mris, fname) ;
fprintf(stderr, "done.\n") ;
}
if (neg_flag)
{
int neg ;
if (mris->patch)
{
mris->status = MRIS_PLANE ;
}
MRIScomputeMetricProperties(mris) ;
neg = MRIScountNegativeTriangles(mris) ;
MRISuseNegCurvature(mris) ;
MRISaverageCurvatures(mris, navgs) ;
sprintf(fname, "%s/%s%s.neg", path,name,suffix) ;
fprintf(stderr, "writing negative vertex curvature to %s...", fname) ;
MRISwriteCurvature(mris, fname) ;
fprintf(stderr, "%d negative triangles\n", neg) ;
fprintf(stderr, "done.\n") ;
{
int vno, fno ;
VERTEX *v ;
FACE *f ;
for (vno = 0 ; vno < mris->nvertices ; vno++)
{
v = &mris->vertices[vno] ;
if (v->ripflag)
{
continue ;
}
neg = 0 ;
for (fno = 0 ; fno < v->num ; fno++)
{
f = &mris->faces[v->f[fno]] ;
if (f->area < 0.0f)
{
neg = 1 ;
}
}
if (neg)
{
fprintf(stdout, "%d\n", vno) ;
}
}
}
}
if (max_flag)
{
MRISuseCurvatureMax(mris) ;
MRISaverageCurvatures(mris, navgs) ;
if (normalize)
{
MRISnormalizeCurvature(mris,which_norm) ;
}
sprintf(fname, "%s/%s%s.max", path,name,suffix) ;
fprintf(stderr, "writing curvature maxima to %s...", fname) ;
MRISwriteCurvature(mris, fname) ;
fprintf(stderr, "done.\n") ;
}
if (min_flag)
{
MRISuseCurvatureMin(mris) ;
MRISaverageCurvatures(mris, navgs) ;
if (normalize)
{
MRISnormalizeCurvature(mris,which_norm) ;
}
sprintf(fname, "%s/%s%s.min", path,name,suffix) ;
fprintf(stderr, "writing curvature minima to %s...", fname) ;
MRISwriteCurvature(mris, fname) ;
fprintf(stderr, "done.\n") ;
}
if (stretch_flag)
{
MRISreadOriginalProperties(mris, NULL) ;
MRISuseCurvatureStretch(mris) ;
MRISaverageCurvatures(mris, navgs) ;
if (normalize)
{
MRISnormalizeCurvature(mris,which_norm) ;
}
sprintf(fname, "%s/%s%s.stretch", path,name,suffix) ;
fprintf(stderr, "writing curvature stretch to %s...", fname) ;
MRISwriteCurvature(mris, fname) ;
fprintf(stderr, "done.\n") ;
}
if (write_flag)
{
MRISuseGaussianCurvature(mris) ;
if (cthresh > 0)
{
MRIShistoThresholdCurvature(mris, cthresh) ;
}
MRISaverageCurvatures(mris, navgs) ;
sprintf(fname, "%s/%s%s.K", path,name, suffix) ;
fprintf(stderr, "writing Gaussian curvature to %s...", fname) ;
if (normalize)
{
MRISnormalizeCurvature(mris,which_norm) ;
}
MRISwriteCurvature(mris, fname) ;
MRISuseMeanCurvature(mris) ;
if (cthresh > 0)
{
MRIShistoThresholdCurvature(mris, cthresh) ;
}
MRISaverageCurvatures(mris, navgs) ;
if (normalize)
{
MRISnormalizeCurvature(mris,which_norm) ;
}
sprintf(fname, "%s/%s%s.H", path,name, suffix) ;
fprintf(stderr, "done.\nwriting mean curvature to %s...", fname) ;
MRISwriteCurvature(mris, fname) ;
fprintf(stderr, "done.\n") ;
}
}
exit(0) ;
return(0) ; /* for ansi */
}
int
main(int argc, char *argv[]) {
char **av, surf_fname[100], *template_fname, *out_fname, *surf_dir,
*hemi, *sphere_name ;
int ac, nargs ;
MRI_SURFACE *mris ;
MRI_SP *mrisp, *mrisp_template ;
/* rkt: check for and handle version tag */
nargs = handle_version_option (argc, argv, "$Id: mris_add_template.c,v 1.8 2011/03/02 00:04:26 nicks Exp $", "$Name: $");
if (nargs && argc - nargs == 1)
exit (0);
argc -= nargs;
Progname = argv[0] ;
ErrorInit(NULL, NULL, NULL) ;
DiagInit(NULL, NULL, NULL) ;
ac = argc ;
av = argv ;
for ( ; argc > 1 && ISOPTION(*argv[1]) ; argc--, argv++) {
nargs = get_option(argc, argv) ;
argc -= nargs ;
argv += nargs ;
}
if (argc < 5)
usage_exit() ;
surf_dir = argv[1] ;
hemi = argv[2] ;
sphere_name = argv[3] ;
out_fname = template_fname = argv[4] ;
if (argc > 5)
out_fname = argv[5] ;
sprintf(surf_fname, "%s/%s.%s", surf_dir, hemi, sphere_name) ;
fprintf(stderr, "reading new surface %s...\n", surf_fname) ;
mris = MRISread(surf_fname) ;
if (!mris)
ErrorExit(ERROR_NOFILE, "%s: could not read surface file %s",
Progname, surf_fname) ;
MRISsaveVertexPositions(mris, ORIGINAL_VERTICES) ;
if (!FileExists(template_fname)) /* first time - create it */
{
fprintf(stderr, "creating new parameterization...\n") ;
mrisp_template = MRISPalloc(scale, PARAM_IMAGES);
} else {
fprintf(stderr, "reading template parameterization from %s...\n",
template_fname) ;
mrisp_template = MRISPread(template_fname) ;
if (!mrisp_template)
ErrorExit(ERROR_NOFILE, "%s: could not open template file %s",
Progname, template_fname) ;
}
/*
first read in inflated surface and use it to build the first template
set.
*/
sprintf(surf_fname, "%s/%s.%s", surf_dir, hemi, INFLATED_NAME) ;
if (MRISreadVertexPositions(mris, surf_fname) != NO_ERROR)
ErrorExit(ERROR_NOFILE, "%s: could not read surface file %s",
Progname, surf_fname) ;
MRISsetNeighborhoodSize(mris, nbrs) ;
MRIScomputeMetricProperties(mris) ;
MRIScomputeSecondFundamentalForm(mris) ;
MRISuseMeanCurvature(mris) ;
MRISaverageCurvatures(mris, navgs) ;
MRISrestoreVertexPositions(mris, ORIGINAL_VERTICES) ;
MRISnormalizeCurvature(mris, which_norm) ;
fprintf(stderr, "computing parameterization for surface %s...\n",surf_fname);
mrisp = MRIStoParameterization(mris, NULL, scale, 0) ;
MRISPcombine(mrisp, mrisp_template, 0) ;
MRISPfree(&mrisp) ;
/*
now do the same thing with the smoothwm curvatures.
*/
sprintf(surf_fname, "%s/%s.%s", surf_dir, hemi, SMOOTH_NAME) ;
if (MRISreadVertexPositions(mris, surf_fname) != NO_ERROR)
ErrorExit(ERROR_NOFILE, "%s: could not read surface file %s",
Progname, surf_fname) ;
MRIScomputeMetricProperties(mris) ;
if (curvature_fname[0])
MRISreadCurvatureFile(mris, curvature_fname) ;
else {
MRIScomputeSecondFundamentalForm(mris) ;
MRISuseMeanCurvature(mris) ;
}
MRISaverageCurvatures(mris, navgs) ;
MRISrestoreVertexPositions(mris, ORIGINAL_VERTICES) ;
if (curvature_fname[0])
fprintf(stderr, "computing parameterization for surface %s (%s)...\n",
surf_fname, curvature_fname);
else
fprintf(stderr, "computing parameterization for surface %s...\n",
surf_fname);
MRISnormalizeCurvature(mris, which_norm) ;
mrisp = MRIStoParameterization(mris, NULL, scale, 0) ;
MRISPcombine(mrisp, mrisp_template, 3) ;
fprintf(stderr, "writing updated template to %s...\n", out_fname) ;
MRISPwrite(mrisp_template, out_fname) ;
MRISPfree(&mrisp) ;
MRISPfree(&mrisp_template) ;
MRISfree(&mris) ;
exit(0) ;
return(0) ; /* for ansi */
}
int
main(int argc, char *argv[])
{
char **av, surf_fname[STRLEN], *template_fname, *hemi, *sphere_name,
*cp, *subject, fname[STRLEN] ;
int ac, nargs, ino, sno, nbad = 0, failed, n,nfields;
VERTEX *v;
VALS_VP *vp;
MRI_SURFACE *mris ;
MRI_SP *mrisp, /* *mrisp_aligned,*/ *mrisp_template ;
INTEGRATION_PARMS parms ;
/* rkt: check for and handle version tag */
nargs = handle_version_option
(argc, argv,
"$Id: mris_make_template.c,v 1.27 2011/03/02 00:04:33 nicks Exp $",
"$Name: stable5 $");
if (nargs && argc - nargs == 1)
exit (0);
argc -= nargs;
memset(&parms, 0, sizeof(parms)) ;
Progname = argv[0] ;
ErrorInit(NULL, NULL, NULL) ;
DiagInit(NULL, NULL, NULL) ;
/* setting default values for vectorial registration */
setParms(&parms);
ac = argc ;
av = argv ;
for ( ; argc > 1 && ISOPTION(*argv[1]) ; argc--, argv++)
{
nargs = get_option(argc, argv,&parms) ;
argc -= nargs ;
argv += nargs ;
}
if (argc < 5) usage_exit() ;
/* multiframe registration */
if (multiframes) parms.flags |= IP_USE_MULTIFRAMES;
if (!strlen(subjects_dir)) /* not specified on command line*/
{
cp = getenv("SUBJECTS_DIR") ;
if (!cp)
ErrorExit(ERROR_BADPARM,
"%s: SUBJECTS_DIR not defined in environment.\n",
Progname) ;
strcpy(subjects_dir, cp) ;
}
hemi = argv[1] ;
sphere_name = argv[2] ;
template_fname = argv[argc-1] ;
if (1 || !FileExists(template_fname)) /* first time - create it */
{
fprintf(stderr, "creating new parameterization...\n") ;
if (multiframes)
{
mrisp_template = MRISPalloc(scale, atlas_size * IMAGES_PER_SURFACE );
/* if (no_rot) /\* don't do rigid alignment *\/ */
/* mrisp_aligned = NULL ; */
/* else */
/* mrisp_aligned = MRISPalloc(scale, PARAM_FRAMES); */
}
else
{
mrisp_template = MRISPalloc(scale, PARAM_IMAGES);
/* if (no_rot) /\* don't do rigid alignment *\/ */
/* mrisp_aligned = NULL ; */
/* else */
/* mrisp_aligned = MRISPalloc(scale, PARAM_IMAGES); */
}
}
else
{
fprintf(stderr, "reading template parameterization from %s...\n",
template_fname) ;
/* mrisp_aligned = NULL ; */
mrisp_template = MRISPread(template_fname) ;
if (!mrisp_template)
ErrorExit(ERROR_NOFILE, "%s: could not open template file %s",
Progname, template_fname) ;
}
argv += 3 ;
argc -= 3 ;
for (ino = 0 ; ino < argc-1 ; ino++)
{
failed = 0 ;
subject = argv[ino] ;
fprintf(stderr, "\nprocessing subject %s (%d of %d)\n", subject,
ino+1, argc-1) ;
sprintf(surf_fname, "%s/%s/surf/%s.%s",
subjects_dir, subject, hemi, sphere_name) ;
fprintf(stderr, "reading spherical surface %s...\n", surf_fname) ;
mris = MRISread(surf_fname) ;
if (!mris)
{
nbad++ ;
ErrorPrintf(ERROR_NOFILE, "%s: could not read surface file %s",
Progname, surf_fname) ;
exit(1) ;
}
if (annot_name)
{
if (MRISreadAnnotation(mris, annot_name) != NO_ERROR)
ErrorExit(ERROR_BADPARM,
"%s: could not read annot file %s",
Progname, annot_name) ;
MRISripMedialWall(mris) ;
}
MRISsaveVertexPositions(mris, CANONICAL_VERTICES) ;
MRIScomputeMetricProperties(mris) ;
MRISstoreMetricProperties(mris) ;
if (Gdiag & DIAG_WRITE)
{
char *cp1 ;
FileNameOnly(template_fname, fname) ;
cp = strchr(fname, '.') ;
if (cp)
{
cp1 = strrchr(fname, '.') ;
if (cp1 && cp1 != cp)
strncpy(parms.base_name, cp+1, cp1-cp-1) ;
else
strcpy(parms.base_name, cp+1) ;
}
else
strcpy(parms.base_name, "template") ;
sprintf(fname, "%s.%s.out", hemi, parms.base_name);
parms.fp = fopen(fname, "w") ;
printf("writing output to '%s'\n", fname) ;
}
/* multiframe registration */
if (multiframes)
{
nfields=parms.nfields;
for ( n = 0; n < mris->nvertices ; n++) /* allocate the VALS_VP
structure */
{
v=&mris->vertices[n];
vp=calloc(1,sizeof(VALS_VP));
vp->nvals=nfields;
vp->orig_vals=(float*)malloc(nfields*sizeof(float)); /* before
blurring */
vp->vals=(float*)malloc(nfields*sizeof(float)); /* values used by
MRISintegrate */
v->vp=(void*)vp;
}
/* load the different fields */
for (n = 0 ; n < parms.nfields ; n++)
{
if (parms.fields[n].name != NULL)
{
sprintf(surf_fname, "%s/%s/%s/%s.%s", subjects_dir,
subject, overlay_dir, hemi, parms.fields[n].name) ;
printf("reading overlay file %s...\n", surf_fname) ;
if (MRISreadValues(mris, surf_fname) != NO_ERROR)
ErrorExit(ERROR_BADPARM, "%s: could not read overlay file %s",
Progname, surf_fname) ;
MRIScopyValuesToCurvature(mris) ;
}
else if (ReturnFieldName(parms.fields[n].field))
{
/* read in precomputed curvature file */
sprintf(surf_fname, "%s/%s/surf/%s.%s", subjects_dir,
subject, hemi, ReturnFieldName(parms.fields[n].field)) ;
// fprintf(stderr,"\nreading field %d from %s(type=%d,frame=%d)\n",parms.fields[n].field,surf_fname,parms.fields[n].type,parms.fields[n].frame);
if (MRISreadCurvatureFile(mris, surf_fname) != NO_ERROR)
{
fprintf(stderr,"\n\nXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX\n");
fprintf(stderr, "%s: could not read curvature file '%s'\n",
Progname, surf_fname) ;
failed = 1;
break;
}
}
else
{ /* compute curvature of surface */
sprintf(surf_fname, "%s/%s/surf/%s.%s", subjects_dir,
subject, hemi, surface_names[parms.fields[n].field]) ;
/*if(parms.fields[n].field==0)
sprintf(fname, "inflated") ;
else
sprintf(fname, "smoothwm") ;*/
//fprintf(stderr,"\ngenerating field %d(type=%d,frame=%d) (from %s)\n",parms.fields[n].field,parms.fields[n].type,parms.fields[n].frame,surf_fname);
// MRISsaveVertexPositions(mris, TMP_VERTICES) ;
if (MRISreadVertexPositions(mris, surf_fname) != NO_ERROR)
{
fprintf(stderr,"\n\nXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX\n");
ErrorPrintf(ERROR_NOFILE, "%s: could not read surface file %s",
Progname, surf_fname) ;
fprintf(stderr,"setting up correlation coefficient to zero\n");
parms.fields[n].l_corr=parms.fields[n].l_pcorr=0.0;
failed=1;
break;
}
if (nbrs > 1) MRISsetNeighborhoodSize(mris, nbrs) ;
MRIScomputeMetricProperties(mris) ;
MRIScomputeSecondFundamentalForm(mris) ;
MRISuseMeanCurvature(mris) ;
MRISaverageCurvatures(mris, navgs) ;
MRISrestoreVertexPositions(mris, CANONICAL_VERTICES) ;
}
/* if(parms.fields[n].field!=SULC_CORR_FRAME)*/
MRISnormalizeField(mris,parms.fields[n].type,
parms.fields[n].which_norm); /* normalize values */
MRISsetCurvaturesToOrigValues(mris,n);
MRISsetCurvaturesToValues(mris,n);
}
if (failed)
{
fprintf(stderr,"\n\nXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX\n");
fprintf(stderr,"Subject %s Failed",subject);
fprintf(stderr,"XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX\n\n");
/* free cal structure*/
for ( n = 0; n < mris->nvertices ; n++)
{
v=&mris->vertices[n];
vp=(VALS_VP*)v->vp;
free(vp->orig_vals);
free(vp->vals);
free(vp);
v->vp=NULL;
}
/* free surface */
MRISfree(&mris);
/* go onto the next subject */
continue;
}
}
if (multiframes && (!no_rot))
{ /* rigid body alignment */
parms.frame_no = 3 ; /* don't use single field correlation functions */
parms.l_corr = parms.l_pcorr = 0.0f ;
parms.mrisp = MRIStoParameterization(mris, NULL, scale, 0) ;
parms.mrisp_template = mrisp_template ;
MRISrigidBodyAlignVectorGlobal(mris, &parms, 1.0, 64.0, 8) ;
if (Gdiag & DIAG_WRITE) MRISwrite(mris, "sphere.rot.global") ;
MRISrigidBodyAlignVectorLocal(mris, &parms) ;
if (Gdiag & DIAG_WRITE) MRISwrite(mris, "sphere.rot.local") ;
MRISPfree(&parms.mrisp) ;
MRISsaveVertexPositions(mris, CANONICAL_VERTICES) ;
};
if ((!multiframes) && (!no_rot) && ino > 0)
{ /* rigid body alignment */
sprintf(surf_fname, "%s/%s/surf/%s.%s",
subjects_dir, subject, hemi, "sulc") ;
if (MRISreadCurvatureFile(mris, surf_fname) != NO_ERROR)
{
ErrorPrintf(Gerror, "%s: could not read curvature file '%s'\n",
Progname, surf_fname) ;
nbad++ ;
MRISfree(&mris) ;
continue ;
}
parms.frame_no = 3 ; /* use sulc for rigid registration */
parms.mrisp = MRIStoParameterization(mris, NULL, scale, 0) ;
parms.mrisp_template = mrisp_template ;
parms.l_corr = 1.0f ;
MRISrigidBodyAlignGlobal(mris, &parms, 1.0, 64.0, 8) ;
if (Gdiag & DIAG_WRITE)
MRISwrite(mris, "sphere.rot.global") ;
MRISrigidBodyAlignLocal(mris, &parms) ;
if (Gdiag & DIAG_WRITE)
MRISwrite(mris, "sphere.rot.local") ;
MRISPfree(&parms.mrisp) ;
MRISsaveVertexPositions(mris, CANONICAL_VERTICES) ;
}
if (multiframes)
{
for (n = 0; n < parms.nfields ; n++)
{
MRISsetOrigValuesToCurvatures(mris,n);
MRISaverageCurvatures(mris, parms.fields[n].navgs) ;
mrisp = MRIStoParameterization(mris, NULL, scale, 0) ;
MRISPcombine(mrisp,
mrisp_template,
parms.fields[n].frame * IMAGES_PER_SURFACE) ;
MRISPfree(&mrisp) ;
}
/* free the VALS_VP structure */
for ( n = 0; n < mris->nvertices ; n++)
{
v=&mris->vertices[n];
vp=(VALS_VP*)v->vp;
free(vp->orig_vals);
free(vp->vals);
free(vp);
v->vp=NULL;
}
MRISfree(&mris) ;
}
else
{
for (sno = 0; sno < SURFACES ; sno++)
{
if (curvature_names[sno]) /* read in precomputed curvature file */
{
sprintf(surf_fname, "%s/%s/surf/%s.%s",
subjects_dir, subject, hemi, curvature_names[sno]) ;
if (MRISreadCurvatureFile(mris, surf_fname) != NO_ERROR)
{
nbad++ ;
ErrorPrintf(Gerror, "%s: could not read curvature file '%s'\n",
Progname, surf_fname) ;
failed = 1 ;
break ;
}
/* the two next lines were not in the original code */
MRISaverageCurvatures(mris, navgs) ;
MRISnormalizeCurvature(mris, which_norm) ;
} else /* compute curvature of surface */
{
sprintf(surf_fname, "%s/%s/surf/%s.%s",
subjects_dir, subject, hemi, surface_names[sno]) ;
if (MRISreadVertexPositions(mris, surf_fname) != NO_ERROR)
{
ErrorPrintf(ERROR_NOFILE, "%s: could not read surface file %s",
Progname, surf_fname) ;
nbad++ ;
failed = 1 ;
break ;
}
if (nbrs > 1)
MRISsetNeighborhoodSize(mris, nbrs) ;
MRIScomputeMetricProperties(mris) ;
MRIScomputeSecondFundamentalForm(mris) ;
MRISuseMeanCurvature(mris) ;
MRISaverageCurvatures(mris, navgs) ;
MRISrestoreVertexPositions(mris, CANONICAL_VERTICES) ;
MRISnormalizeCurvature(mris, which_norm) ;
}
fprintf(stderr, "computing parameterization for surface %s...\n",
surf_fname);
if (failed)
{
continue ;
MRISfree(&mris) ;
}
mrisp = MRIStoParameterization(mris, NULL, scale, 0) ;
MRISPcombine(mrisp, mrisp_template, sno*3) ;
MRISPfree(&mrisp) ;
}
MRISfree(&mris) ;
}
}
#if 0
if (mrisp_aligned) /* new parameterization - use rigid alignment */
{
MRI_SP *mrisp_tmp ;
if (Gdiag & DIAG_WRITE)
{
char *cp1 ;
FileNameOnly(template_fname, fname) ;
cp = strchr(fname, '.') ;
if (cp)
{
cp1 = strrchr(fname, '.') ;
if (cp1 && cp1 != cp)
strncpy(parms.base_name, cp+1, cp1-cp-1) ;
else
strcpy(parms.base_name, cp+1) ;
}
else
strcpy(parms.base_name, "template") ;
sprintf(fname, "%s.%s.out", hemi, parms.base_name);
parms.fp = fopen(fname, "w") ;
printf("writing output to '%s'\n", fname) ;
}
for (ino = 0 ; ino < argc-1 ; ino++)
{
subject = argv[ino] ;
if (Gdiag & DIAG_WRITE)
fprintf(parms.fp, "processing subject %s\n", subject) ;
fprintf(stderr, "processing subject %s\n", subject) ;
sprintf(surf_fname, "%s/%s/surf/%s.%s",
subjects_dir, subject, hemi, sphere_name) ;
fprintf(stderr, "reading spherical surface %s...\n", surf_fname) ;
mris = MRISread(surf_fname) ;
if (!mris)
ErrorExit(ERROR_NOFILE, "%s: could not read surface file %s",
Progname, surf_fname) ;
MRIScomputeMetricProperties(mris) ;
MRISstoreMetricProperties(mris) ;
MRISsaveVertexPositions(mris, ORIGINAL_VERTICES) ;
sprintf(surf_fname, "%s/%s/surf/%s.%s",
subjects_dir, subject, hemi, "sulc") ;
if (MRISreadCurvatureFile(mris, surf_fname) != NO_ERROR)
ErrorExit(Gerror, "%s: could not read curvature file '%s'\n",
Progname, surf_fname) ;
parms.frame_no = 3 ;
parms.mrisp = MRIStoParameterization(mris, NULL, scale, 0) ;
parms.mrisp_template = mrisp_template ;
parms.l_corr = 1.0f ;
MRISrigidBodyAlignGlobal(mris, &parms, 1.0, 32.0, 8) ;
if (Gdiag & DIAG_WRITE)
MRISwrite(mris, "sphere.rot.global") ;
MRISrigidBodyAlignLocal(mris, &parms) ;
if (Gdiag & DIAG_WRITE)
MRISwrite(mris, "sphere.rot.local") ;
MRISPfree(&parms.mrisp) ;
#if 0
/* write out rotated surface */
sprintf(surf_fname, "%s.rot", mris->fname) ;
fprintf(stderr, "writing out rigidly aligned surface to '%s'\n",
surf_fname) ;
MRISwrite(mris, surf_fname) ;
#endif
/* now generate new parameterization using the optimal alignment */
for (sno = 0; sno < SURFACES ; sno++)
{
if (curvature_names[sno]) /* read in precomputed curvature file */
{
sprintf(surf_fname, "%s/%s/surf/%s.%s",
subjects_dir, subject, hemi, curvature_names[sno]) ;
if (MRISreadCurvatureFile(mris, surf_fname) != NO_ERROR)
ErrorExit(Gerror, "%s: could not read curvature file '%s'\n",
Progname, surf_fname) ;
} else /* compute curvature of surface */
{
sprintf(surf_fname, "%s/%s/surf/%s.%s",
subjects_dir, subject, hemi, surface_names[sno]) ;
if (MRISreadVertexPositions(mris, surf_fname) != NO_ERROR)
ErrorExit(ERROR_NOFILE, "%s: could not read surface file %s",
Progname, surf_fname) ;
if (nbrs > 1)
MRISsetNeighborhoodSize(mris, nbrs) ;
MRIScomputeMetricProperties(mris) ;
MRIScomputeSecondFundamentalForm(mris) ;
MRISuseMeanCurvature(mris) ;
MRISaverageCurvatures(mris, navgs) ;
MRISrestoreVertexPositions(mris, ORIGINAL_VERTICES) ;
MRISnormalizeCurvature(mris) ;
}
fprintf(stderr, "computing parameterization for surface %s...\n",
surf_fname);
mrisp = MRIStoParameterization(mris, NULL, scale, 0) ;
MRISPcombine(mrisp, mrisp_aligned, sno*3) ;
MRISPfree(&mrisp) ;
}
MRISfree(&mris) ;
}
if (Gdiag & DIAG_WRITE)
fclose(parms.fp) ;
mrisp_tmp = mrisp_aligned ;
mrisp_aligned = mrisp_template ;
mrisp_template = mrisp_tmp ;
MRISPfree(&mrisp_aligned) ;
}
#endif
fprintf(stderr,
"writing updated template with %d subjects to %s...\n",
argc-1-nbad, template_fname) ;
MRISPwrite(mrisp_template, template_fname) ;
MRISPfree(&mrisp_template) ;
exit(0) ;
return(0) ; /* for ansi */
}
int
main(int argc, char *argv[]) {
MRI_SURFACE *mris ;
char **av, *curv_name, *surf_name, *hemi, fname[STRLEN],
*cp, *subject_name, subjects_dir[STRLEN],
**c1_subjects, **c2_subjects ;
int ac, nargs, n, num_class1, num_class2, i, nvertices,
avgs, max_snr_avgs, nlabels = 0, done ;
float **c1_thickness, **c2_thickness, *curvs, *total_mean,
*c1_mean, *c2_mean,
*class_mean, *c1_var, *c2_var, *class_var,*pvals,
**c1_avg_thickness,
*vbest_snr, *vbest_avgs, *vtotal_var, *vsnr, **c2_avg_thickness,
*vbest_pvalues, current_min_label_area, current_fthresh ;
MRI_SP *mrisp ;
LABEL *area, **labels = NULL ;
FILE *fp = NULL ;
double snr, max_snr ;
struct timeb start ;
int msec, minutes, seconds ;
double **c1_label_thickness, **c2_label_thickness ;
int *sorted_indices = NULL, vno ;
float *test_thickness, *test_avg_thickness ;
double label_avg ;
/* rkt: check for and handle version tag */
nargs = handle_version_option (argc, argv, "$Id: mris_classify_thickness.c,v 1.8 2011/03/02 00:04:29 nicks Exp $", "$Name: stable5 $");
if (nargs && argc - nargs == 1)
exit (0);
argc -= nargs;
if (write_flag && DIAG_VERBOSE_ON)
fp = fopen("scalespace.dat", "w") ;
Progname = argv[0] ;
ErrorInit(NULL, NULL, NULL) ;
DiagInit(NULL, NULL, NULL) ;
ac = argc ;
av = argv ;
for ( ; argc > 1 && ISOPTION(*argv[1]) ; argc--, argv++) {
nargs = get_option(argc, argv) ;
argc -= nargs ;
argv += nargs ;
}
TimerStart(&start) ;
/* subject_name hemi surface curvature */
if (argc < 7)
usage_exit() ;
if (output_subject == NULL)
ErrorExit(ERROR_BADPARM,
"output subject must be specified with -o <subject name>");
cp = getenv("SUBJECTS_DIR") ;
if (!cp)
ErrorExit(ERROR_BADPARM, "%s: SUBJECTS_DIR not defined in environment",
Progname) ;
strcpy(subjects_dir, cp) ;
hemi = argv[1] ;
surf_name = argv[2] ;
curv_name = argv[3] ;
#define ARGV_OFFSET 4
/* first determine the number of subjects in each class */
num_class1 = 0 ;
n = ARGV_OFFSET ;
do {
num_class1++ ;
n++ ;
if (argv[n] == NULL || n >= argc)
ErrorExit(ERROR_BADPARM, "%s: must spectify ':' between class lists",
Progname) ;
} while (argv[n][0] != ':') ;
/* find # of vertices in output subject surface */
sprintf(fname, "%s/%s/surf/%s.%s",
subjects_dir,output_subject,hemi,surf_name);
mris = MRISread(fname) ;
if (!mris)
ErrorExit(ERROR_NOFILE, "%s: could not read surface file %s",
Progname, fname) ;
nvertices = mris->nvertices ;
MRISfree(&mris) ;
total_mean = (float *)calloc(nvertices, sizeof(float)) ;
if (!total_mean)
ErrorExit(ERROR_NOMEMORY,
"%s: could not allocate mean list of %d curvatures",
Progname, n, nvertices) ;
c1_mean = (float *)calloc(nvertices, sizeof(float)) ;
if (!c1_mean)
ErrorExit(ERROR_NOMEMORY,
"%s: could not allocate c1 mean list of %d curvatures",
Progname, n, nvertices) ;
pvals = (float *)calloc(nvertices, sizeof(float)) ;
if (!pvals)
ErrorExit(ERROR_NOMEMORY,
"%s: could not allocate pvals",
Progname, n, nvertices) ;
c2_mean = (float *)calloc(nvertices, sizeof(float)) ;
if (!c2_mean)
ErrorExit(ERROR_NOMEMORY,
"%s: could not allocate c2 mean list of %d curvatures",
Progname, n, nvertices) ;
c1_var = (float *)calloc(nvertices, sizeof(float)) ;
if (!c1_var)
ErrorExit(ERROR_NOMEMORY,
"%s: could not allocate c1 var list of %d curvatures",
Progname, n, nvertices) ;
c2_var = (float *)calloc(nvertices, sizeof(float)) ;
if (!c2_var)
ErrorExit(ERROR_NOMEMORY,
"%s: could not allocate c2 var list of %d curvatures",
Progname, n, nvertices) ;
num_class2 = 0 ;
n++ ; /* skip ':' */
if (n >= argc)
ErrorExit(ERROR_BADPARM, "%s: class2 list empty", Progname) ;
do {
num_class2++ ;
n++ ;
if (n >= argc)
break ;
} while (argv[n] != NULL) ;
fprintf(stderr, "%d subjects in class 1, %d subjects in class 2\n",
num_class1, num_class2) ;
c1_subjects = (char **)calloc(num_class1, sizeof(char *)) ;
c1_thickness = (float **)calloc(num_class1, sizeof(char *)) ;
c1_avg_thickness = (float **)calloc(num_class1, sizeof(char *)) ;
c2_subjects = (char **)calloc(num_class2, sizeof(char *)) ;
c2_thickness = (float **)calloc(num_class2, sizeof(char *)) ;
c2_avg_thickness = (float **)calloc(num_class2, sizeof(char *)) ;
for (n = 0 ; n < num_class1 ; n++) {
c1_subjects[n] = argv[ARGV_OFFSET+n] ;
c1_thickness[n] = (float *)calloc(nvertices, sizeof(float)) ;
c1_avg_thickness[n] = (float *)calloc(nvertices, sizeof(float)) ;
if (!c1_thickness[n] || !c1_avg_thickness[n])
ErrorExit(ERROR_NOMEMORY,
"%s: could not allocate %dth list of %d curvatures",
Progname, n, nvertices) ;
strcpy(c1_subjects[n], argv[ARGV_OFFSET+n]) ;
/* fprintf(stderr, "class1[%d] - %s\n", n, c1_subjects[n]) ;*/
}
i = n+1+ARGV_OFFSET ; /* starting index */
for (n = 0 ; n < num_class2 ; n++) {
c2_subjects[n] = argv[i+n] ;
c2_thickness[n] = (float *)calloc(nvertices, sizeof(float)) ;
c2_avg_thickness[n] = (float *)calloc(nvertices, sizeof(float)) ;
if (!c2_thickness[n] || !c2_avg_thickness[n])
ErrorExit(ERROR_NOMEMORY,
"%s: could not allocate %dth list of %d curvatures",
Progname, n, nvertices) ;
strcpy(c2_subjects[n], argv[i+n]) ;
/* fprintf(stderr, "class2[%d] - %s\n", n, c2_subjects[n]) ;*/
}
if (label_name) {
area = LabelRead(output_subject, label_name) ;
if (!area)
ErrorExit(ERROR_NOFILE, "%s: could not read label %s", Progname,
label_name) ;
} else
area = NULL ;
if (read_dir) {
sprintf(fname, "%s/%s/surf/%s.%s",
subjects_dir,output_subject,hemi,surf_name);
mris = MRISread(fname) ;
if (!mris)
ErrorExit(ERROR_NOFILE, "%s: could not read surface file %s",
Progname, fname) ;
MRISsaveVertexPositions(mris, CANONICAL_VERTICES) ;
/* real all the curvatures in for group1 */
for (n = 0 ; n < num_class1+num_class2 ; n++) {
/* transform each subject's curvature into the output subject's space */
subject_name = n < num_class1 ? c1_subjects[n]:c2_subjects[n-num_class1];
fprintf(stderr, "reading subject %d of %d: %s\n",
n+1, num_class1+num_class2, subject_name) ;
sprintf(fname, "%s/%s.%s", read_dir,hemi,subject_name);
if (MRISreadValues(mris, fname) != NO_ERROR)
ErrorExit(Gerror,
"%s: could not read curvature file %s",Progname,fname);
if (area)
MRISmaskNotLabel(mris, area) ;
curvs = (n < num_class1) ? c1_thickness[n] : c2_thickness[n-num_class1] ;
class_mean = (n < num_class1) ? c1_mean : c2_mean ;
class_var = (n < num_class1) ? c1_var : c2_var ;
MRISexportValVector(mris, curvs) ;
cvector_accumulate(curvs, total_mean, nvertices) ;
cvector_accumulate(curvs, class_mean, nvertices) ;
cvector_accumulate_square(curvs, class_var, nvertices) ;
}
} else {
/* real all the curvatures in for group1 */
for (n = 0 ; n < num_class1+num_class2 ; n++) {
/* transform each subject's curvature into the output subject's space */
subject_name = n < num_class1 ? c1_subjects[n]:c2_subjects[n-num_class1];
fprintf(stderr, "reading subject %d of %d: %s\n",
n+1, num_class1+num_class2, subject_name) ;
sprintf(fname, "%s/%s/surf/%s.%s",
subjects_dir,subject_name,hemi,surf_name);
mris = MRISread(fname) ;
if (!mris)
ErrorExit(ERROR_NOFILE, "%s: could not read surface file %s",
Progname, fname) ;
MRISsaveVertexPositions(mris, CANONICAL_VERTICES) ;
if (strchr(curv_name, '/') != NULL)
strcpy(fname, curv_name) ; /* full path specified */
else
sprintf(fname,"%s/%s/surf/%s.%s",
subjects_dir,subject_name,hemi,curv_name);
if (MRISreadCurvatureFile(mris, fname) != NO_ERROR)
ErrorExit(Gerror,"%s: could no read curvature file %s",Progname,fname);
mrisp = MRIStoParameterization(mris, NULL, 1, 0) ;
MRISfree(&mris) ;
sprintf(fname, "%s/%s/surf/%s.%s",
subjects_dir,output_subject,hemi,surf_name);
mris = MRISread(fname) ;
if (!mris)
ErrorExit(ERROR_NOFILE, "%s: could not read surface file %s",
Progname, fname) ;
MRISfromParameterization(mrisp, mris, 0) ;
if (area)
MRISmaskNotLabel(mris, area) ;
curvs = (n < num_class1) ? c1_thickness[n] : c2_thickness[n-num_class1] ;
class_mean = (n < num_class1) ? c1_mean : c2_mean ;
class_var = (n < num_class1) ? c1_var : c2_var ;
MRISextractCurvatureVector(mris, curvs) ;
cvector_accumulate(curvs, total_mean, nvertices) ;
cvector_accumulate(curvs, class_mean, nvertices) ;
cvector_accumulate_square(curvs, class_var, nvertices) ;
MRISPfree(&mrisp) ;
MRISfree(&mris) ;
}
}
/* compute within-group means, and total mean */
cvector_normalize(total_mean, num_class1+num_class2, nvertices) ;
cvector_normalize(c1_mean, num_class1, nvertices) ;
cvector_normalize(c2_mean, num_class2, nvertices) ;
cvector_compute_variance(c1_var, c1_mean, num_class1, nvertices) ;
cvector_compute_variance(c2_var, c2_mean, num_class2, nvertices) ;
cvector_compute_t_test(c1_mean, c1_var, c2_mean, c2_var,
num_class1, num_class2, pvals, nvertices) ;
sprintf(fname, "%s/%s/surf/%s.%s",
subjects_dir,output_subject,hemi,surf_name);
fprintf(stderr, "reading output surface %s...\n", fname) ;
mris = MRISread(fname) ;
if (!mris)
ErrorExit(ERROR_NOFILE, "%s: could not read surface file %s",
Progname, fname) ;
if (area)
MRISripNotLabel(mris, area) ;
vbest_snr = cvector_alloc(nvertices) ;
vbest_pvalues = cvector_alloc(nvertices) ;
vbest_avgs = cvector_alloc(nvertices) ;
vtotal_var = cvector_alloc(nvertices) ;
vsnr = cvector_alloc(nvertices) ;
if (read_dir == NULL) /* recompute everything */
{
if (use_buggy_snr)
cvector_multiply_variances(c1_var, c2_var, num_class1, num_class2,
vtotal_var, nvertices) ;
else
cvector_add_variances(c1_var, c2_var, num_class1, num_class2,
vtotal_var, nvertices) ;
if (use_no_distribution)
snr = cvector_compute_dist_free_snr(c1_thickness, num_class1,
c2_thickness, num_class2,
c1_mean, c2_mean,
vsnr, nvertices, &i);
else
snr = cvector_compute_snr(c1_mean, c2_mean, vtotal_var, vsnr, nvertices,
&i, 0.0f);
fprintf(stderr,
"raw SNR %2.2f, n=%2.4f, d=%2.4f, vno=%d\n",
sqrt(snr), c1_mean[i]-c2_mean[i], sqrt(vtotal_var[i]), i) ;
max_snr = snr ;
max_snr_avgs = 0 ;
cvector_track_best_snr(vsnr, vbest_snr, vbest_avgs, 0, nvertices) ;
for (n = 0 ; n < num_class1 ; n++)
cvector_copy(c1_thickness[n], c1_avg_thickness[n], nvertices) ;
for (n = 0 ; n < num_class2 ; n++)
cvector_copy(c2_thickness[n], c2_avg_thickness[n], nvertices) ;
/* now incrementally average the data, keeping track of the best
snr at each location, and at what scale it occurred. vbest_avgs
and vbest_snr will contain the scale and the snr at that scale.
*/
for (avgs = 1 ; avgs <= max_avgs ; avgs++) {
/* c?_avg_thickness is the thickness at the current scale */
if (!(avgs % 50))
fprintf(stderr, "testing %d averages...\n", avgs) ;
cvector_clear(c1_mean, nvertices) ;
cvector_clear(c2_mean, nvertices) ;
cvector_clear(c1_var, nvertices) ;
cvector_clear(c2_var, nvertices) ;
cvector_clear(total_mean, nvertices) ;
for (n = 0 ; n < num_class1 ; n++) {
MRISimportCurvatureVector(mris, c1_avg_thickness[n]) ;
MRISaverageCurvatures(mris, 1) ;
MRISextractCurvatureVector(mris, c1_avg_thickness[n]) ;
cvector_accumulate(c1_avg_thickness[n], total_mean, nvertices) ;
cvector_accumulate(c1_avg_thickness[n], c1_mean, nvertices) ;
cvector_accumulate_square(c1_avg_thickness[n], c1_var, nvertices) ;
}
for (n = 0 ; n < num_class2 ; n++) {
MRISimportCurvatureVector(mris, c2_avg_thickness[n]) ;
MRISaverageCurvatures(mris, 1) ;
MRISextractCurvatureVector(mris, c2_avg_thickness[n]) ;
cvector_accumulate(c2_avg_thickness[n], total_mean, nvertices) ;
cvector_accumulate(c2_avg_thickness[n], c2_mean, nvertices) ;
cvector_accumulate_square(c2_avg_thickness[n], c2_var, nvertices) ;
}
cvector_normalize(total_mean, num_class1+num_class2, nvertices) ;
cvector_normalize(c1_mean, num_class1, nvertices) ;
cvector_normalize(c2_mean, num_class2, nvertices) ;
cvector_compute_variance(c1_var, c1_mean, num_class1, nvertices) ;
cvector_compute_variance(c2_var, c2_mean, num_class2, nvertices) ;
if (use_buggy_snr)
cvector_multiply_variances(c1_var, c2_var, num_class1, num_class2,
vtotal_var, nvertices) ;
else
cvector_add_variances(c1_var, c2_var, num_class1, num_class2,
vtotal_var, nvertices) ;
if (use_no_distribution)
snr =
cvector_compute_dist_free_snr(c1_avg_thickness,num_class1,
c2_avg_thickness, num_class2, c1_mean,
c2_mean, vsnr, nvertices, &i);
else
snr =
cvector_compute_snr(c1_mean, c2_mean, vtotal_var, vsnr, nvertices,&i,
bonferroni ? log((double)avgs) : 0.0f);
if (write_flag && DIAG_VERBOSE_ON) {
fprintf(fp, "%d %2.1f %2.2f %2.2f %2.2f ",
avgs, sqrt((float)avgs), sqrt(snr), c1_mean[i]-c2_mean[i],
sqrt(vtotal_var[i])) ;
fflush(fp) ;
for (n = 0 ; n < num_class1 ; n++)
fprintf(fp, "%2.2f ", c1_avg_thickness[n][i]) ;
for (n = 0 ; n < num_class2 ; n++)
fprintf(fp, "%2.2f ", c2_avg_thickness[n][i]) ;
fprintf(fp, "\n") ;
fclose(fp) ;
}
if (snr > max_snr) {
fprintf(stderr,
"new max SNR found at avgs=%d (%2.1f mm)=%2.1f, n=%2.4f, "
"d=%2.4f, vno=%d\n",
avgs, sqrt((float)avgs), sqrt(snr), c1_mean[i]-c2_mean[i],
sqrt(vtotal_var[i]), i) ;
max_snr = snr ;
max_snr_avgs = avgs ;
}
cvector_track_best_snr(vsnr, vbest_snr, vbest_avgs, avgs, nvertices) ;
}
if (compute_stats)
cvector_compute_t(vbest_snr, vbest_pvalues,num_class1+num_class2,
nvertices) ;
printf("max snr=%2.2f at %d averages\n", max_snr, max_snr_avgs) ;
if (write_flag) {
MRISimportValVector(mris, vbest_snr) ;
sprintf(fname, "./%s.%s_best_snr", hemi,prefix) ;
MRISwriteValues(mris, fname) ;
MRISimportValVector(mris, vbest_avgs) ;
sprintf(fname, "./%s.%s_best_avgs", hemi, prefix) ;
MRISwriteValues(mris, fname) ;
if (compute_stats) {
MRISimportValVector(mris, vbest_pvalues) ;
sprintf(fname, "./%s.%s_best_pval", hemi,prefix) ;
MRISwriteValues(mris, fname) ;
}
}
}
else /* read from directory containing precomputed optimal values */
{
sprintf(fname, "%s/%s.%s_best_snr", read_dir, hemi, prefix) ;
if (MRISreadValues(mris, fname) != NO_ERROR)
ErrorExit(Gerror, "%s: MRISreadValues(%s) failed",Progname,fname) ;
MRISexportValVector(mris, vbest_snr) ;
sprintf(fname, "%s/%s.%s_best_avgs", read_dir, hemi, prefix) ;
if (MRISreadValues(mris, fname) != NO_ERROR)
ErrorExit(Gerror, "%s: MRISreadValues(%s) failed",Progname,fname) ;
MRISexportValVector(mris, vbest_avgs) ;
}
if (write_dir) {
sprintf(fname, "%s/%s.%s_best_snr", write_dir, hemi,prefix) ;
MRISimportValVector(mris, vbest_snr) ;
if (MRISwriteValues(mris, fname) != NO_ERROR)
ErrorExit(Gerror, "%s: MRISwriteValues(%s) failed",Progname,fname) ;
sprintf(fname, "%s/%s.%s_best_avgs", write_dir, hemi, prefix) ;
MRISimportValVector(mris, vbest_avgs) ;
if (MRISwriteValues(mris, fname) != NO_ERROR)
ErrorExit(Gerror, "%s: MRISwriteValues(%s) failed",Progname,fname) ;
}
if (nsort < -1)
nsort = mris->nvertices ;
if (nsort <= 0) {
nlabels = 0 ;
current_min_label_area = min_label_area ;
for (done = 0, current_fthresh = fthresh ;
!FZERO(current_fthresh) && !done ;
current_fthresh *= 0.95) {
int npos_labels, nneg_labels ;
LABEL **pos_labels, **neg_labels ;
for (current_min_label_area = min_label_area ;
current_min_label_area > 0.5 ;
current_min_label_area *= 0.75) {
MRISclearMarks(mris) ;
sprintf(fname, "%s-%s_thickness", hemi, prefix ? prefix : "") ;
mark_thresholded_vertices(mris, vbest_snr, vbest_avgs,current_fthresh);
segment_and_write_labels(output_subject, fname, mris,
&pos_labels, &npos_labels, 0,
current_min_label_area) ;
MRISclearMarks(mris) ;
mark_thresholded_vertices(mris, vbest_snr,vbest_avgs,-current_fthresh);
segment_and_write_labels(output_subject, fname, mris, &neg_labels,
&nneg_labels, npos_labels,
current_min_label_area) ;
nlabels = nneg_labels + npos_labels ;
if (nlabels) {
labels = (LABEL **)calloc(nlabels, sizeof(LABEL *)) ;
for (i = 0 ; i < npos_labels ; i++)
labels[i] = pos_labels[i] ;
for (i = 0 ; i < nneg_labels ; i++)
labels[i+npos_labels] = neg_labels[i] ;
free(pos_labels) ;
free(neg_labels) ;
}
done = (nlabels >= min_labels) ;
if (done) /* found enough points */
break ;
/* couldn't find enough points - free stuff and try again */
for (i = 0 ; i < nlabels ; i++)
LabelFree(&labels[i]) ;
if (nlabels)
free(labels) ;
#if 0
fprintf(stderr,"%d labels found (min %d), reducing constraints...\n",
nlabels, min_labels) ;
#endif
}
}
printf("%d labels found with F > %2.1f and area > %2.0f\n",
nlabels, current_fthresh, current_min_label_area) ;
for (i = 0 ; i < nlabels ; i++)
fprintf(stderr, "label %d: %d points, %2.1f mm\n",
i, labels[i]->n_points, LabelArea(labels[i], mris)) ;
}
/* read or compute thickness at optimal scale and put it into
c?_avg_thickness.
*/
if (!read_dir) {
fprintf(stderr, "extracting thickness at optimal scale...\n") ;
/* now build feature vectors for each subject */
extract_thickness_at_best_scale(mris, c1_avg_thickness, vbest_avgs,
c1_thickness, nvertices, num_class1);
fprintf(stderr, "extracting thickness for class 2...\n") ;
extract_thickness_at_best_scale(mris, c2_avg_thickness, vbest_avgs,
c2_thickness, nvertices, num_class2);
} else /* read in precomputed optimal thicknesses */
{
char fname[STRLEN] ;
fprintf(stderr, "reading precomputed thickness vectors\n") ;
for (n = 0 ; n < num_class1 ; n++) {
sprintf(fname, "%s/%s.%s", read_dir, hemi, argv[ARGV_OFFSET+n]) ;
fprintf(stderr, "reading thickness vector from %s...\n", fname) ;
if (MRISreadValues(mris, fname) != NO_ERROR)
ErrorExit(Gerror, "%s: could not read thickness file %s",
Progname,fname) ;
MRISexportValVector(mris, c1_avg_thickness[n]) ;
}
for (n = 0 ; n < num_class2 ; n++) {
sprintf(fname, "%s/%s.%s", read_dir, hemi,
argv[n+num_class1+1+ARGV_OFFSET]) ;
fprintf(stderr, "reading curvature vector from %s...\n", fname) ;
if (MRISreadValues(mris, fname) != NO_ERROR)
ErrorExit(Gerror, "%s: could not read thickness file %s",
Progname,fname) ;
MRISexportValVector(mris, c2_avg_thickness[n]) ;
}
}
if (write_dir) /* write out optimal thicknesses */
{
char fname[STRLEN] ;
for (n = 0 ; n < num_class1 ; n++) {
sprintf(fname, "%s/%s.%s", write_dir, hemi, argv[ARGV_OFFSET+n]) ;
fprintf(stderr, "writing curvature vector to %s...\n", fname) ;
MRISimportValVector(mris, c1_avg_thickness[n]) ;
MRISwriteValues(mris, fname) ;
}
for (n = 0 ; n < num_class2 ; n++) {
sprintf(fname, "%s/%s.%s", write_dir, hemi,
argv[n+num_class1+1+ARGV_OFFSET]) ;
fprintf(stderr, "writing curvature vector to %s...\n", fname) ;
MRISimportValVector(mris, c2_avg_thickness[n]) ;
MRISwriteValues(mris, fname) ;
}
}
/* should free c?_thickness here */
if (nsort <= 0) {
/* We have the thickness values at the most powerful scale stored for
each subject in the c1_avg_thickness and c2_avg_thickness vectors.
Now collapse them across each label and build feature vector for
classification.
*/
c1_label_thickness = (double **)calloc(num_class1, sizeof(double *)) ;
c2_label_thickness = (double **)calloc(num_class2, sizeof(double *)) ;
for (n = 0 ; n < num_class1 ; n++)
c1_label_thickness[n] = (double *)calloc(nlabels, sizeof(double)) ;
for (n = 0 ; n < num_class2 ; n++)
c2_label_thickness[n] = (double *)calloc(nlabels, sizeof(double)) ;
fprintf(stderr, "collapsing thicknesses within labels for class 1\n") ;
for (n = 0 ; n < num_class1 ; n++)
for (i = 0 ; i < nlabels ; i++)
c1_label_thickness[n][i] =
cvector_average_in_label(c1_avg_thickness[n], labels[i], nvertices) ;
fprintf(stderr, "collapsing thicknesses within labels for class 2\n") ;
for (n = 0 ; n < num_class2 ; n++)
for (i = 0 ; i < nlabels ; i++)
c2_label_thickness[n][i] =
cvector_average_in_label(c2_avg_thickness[n], labels[i], nvertices) ;
sprintf(fname, "%s_%s_class1.dat", hemi,prefix) ;
fprintf(stderr, "writing class 1 info to %s...\n", fname) ;
fp = fopen(fname, "w") ;
for (i = 0 ; i < nlabels ; i++) /* for each row */
{
for (n = 0 ; n < num_class1 ; n++) /* for each column */
fprintf(fp, "%2.2f ", c1_label_thickness[n][i]) ;
fprintf(fp, "\n") ;
}
fclose(fp) ;
sprintf(fname, "%s_%s_class2.dat", hemi,prefix) ;
fprintf(stderr, "writing class 2 info to %s...\n", fname) ;
fp = fopen(fname, "w") ;
for (i = 0 ; i < nlabels ; i++) {
for (n = 0 ; n < num_class2 ; n++)
fprintf(fp, "%2.2f ", c2_label_thickness[n][i]) ;
fprintf(fp, "\n") ;
}
fclose(fp) ;
} else {
sorted_indices = cvector_sort(vbest_snr, nvertices) ;
vno = sorted_indices[0] ;
write_vertex_data("c1.dat", vno, c1_avg_thickness,num_class1);
write_vertex_data("c2.dat", vno, c2_avg_thickness,num_class2);
printf("sorting complete\n") ;
/* re-write class means at these locations */
sprintf(fname, "%s_%s_class1.dat", hemi,prefix) ;
fprintf(stderr, "writing class 1 info to %s...\n", fname) ;
fp = fopen(fname, "w") ;
for (i = 0 ; i < nsort ; i++) {
for (n = 0 ; n < num_class1 ; n++)
fprintf(fp, "%2.2f ", c1_avg_thickness[n][sorted_indices[i]]) ;
fprintf(fp, "\n") ;
}
fclose(fp) ;
sprintf(fname, "%s_%s_class2.dat", hemi,prefix) ;
fprintf(stderr, "writing class 2 info to %s...\n", fname) ;
fp = fopen(fname, "w") ;
for (i = 0 ; i < nsort ; i++) {
for (n = 0 ; n < num_class2 ; n++)
fprintf(fp, "%2.2f ", c2_avg_thickness[n][sorted_indices[i]]) ;
fprintf(fp, "\n") ;
}
fclose(fp) ;
}
if (test_subject) {
test_thickness = cvector_alloc(nvertices) ;
test_avg_thickness = cvector_alloc(nvertices) ;
MRISfree(&mris) ;
fprintf(stderr, "reading subject %s\n", test_subject) ;
sprintf(fname, "%s/%s/surf/%s.%s",
subjects_dir,test_subject,hemi,surf_name);
mris = MRISread(fname) ;
if (!mris)
ErrorExit(ERROR_NOFILE, "%s: could not read surface file %s",
Progname, fname) ;
MRISsaveVertexPositions(mris, CANONICAL_VERTICES) ;
if (strchr(curv_name, '/') != NULL)
strcpy(fname, curv_name) ; /* full path specified */
else
sprintf(fname,"%s/%s/surf/%s.%s",
subjects_dir,test_subject,hemi,curv_name);
if (MRISreadCurvatureFile(mris, fname) != NO_ERROR)
ErrorExit(Gerror,"%s: could no read curvature file %s",Progname,fname);
mrisp = MRIStoParameterization(mris, NULL, 1, 0) ;
MRISfree(&mris) ;
sprintf(fname, "%s/%s/surf/%s.%s",
subjects_dir,output_subject,hemi,surf_name);
mris = MRISread(fname) ;
if (!mris)
ErrorExit(ERROR_NOFILE, "%s: could not read surface file %s",
Progname, fname) ;
MRISfromParameterization(mrisp, mris, 0) ;
if (area)
MRISmaskNotLabel(mris, area) ;
MRISextractCurvatureVector(mris, test_thickness) ;
for (avgs = 0 ; avgs <= max_avgs ; avgs++) {
cvector_extract_best_avg(vbest_avgs, test_thickness,test_avg_thickness,
avgs-1, nvertices) ;
MRISimportCurvatureVector(mris, test_thickness) ;
MRISaverageCurvatures(mris, 1) ;
MRISextractCurvatureVector(mris, test_thickness) ;
}
if (nsort <= 0) {
sprintf(fname, "%s_%s.dat", hemi,test_subject) ;
fprintf(stderr, "writing test subject feature vector to %s...\n",
fname) ;
fp = fopen(fname, "w") ;
for (i = 0 ; i < nlabels ; i++) /* for each row */
{
label_avg =
cvector_average_in_label(test_avg_thickness, labels[i], nvertices) ;
fprintf(fp, "%2.2f\n", label_avg) ;
}
fclose(fp) ;
} else /* use sorting instead of connected areas */
{
double classification, offset, w ;
int total_correct, total_wrong, first_wrong, vno ;
sprintf(fname, "%s_%s.dat", hemi,test_subject) ;
fprintf(stderr, "writing test subject feature vector to %s...\n",
fname) ;
fp = fopen(fname, "w") ;
first_wrong = -1 ;
total_wrong = total_correct = 0 ;
for (i = 0 ; i < nsort ; i++) {
vno = sorted_indices[i] ;
fprintf(fp, "%2.2f\n ", test_avg_thickness[sorted_indices[i]]) ;
offset = (c1_mean[vno]+c2_mean[vno])/2.0 ;
w = (c1_mean[vno]-c2_mean[vno]) ;
classification = (test_avg_thickness[vno] - offset) * w ;
if (((classification < 0) && (true_class == 1)) ||
((classification > 0) && (true_class == 2))) {
total_wrong++ ;
if (first_wrong < 0)
first_wrong = i ;
} else
total_correct++ ;
}
fclose(fp) ;
fprintf(stderr, "%d of %d correct = %2.1f%% (first wrong %d (%d)),"
"min snr=%2.1f\n",
total_correct, total_correct+total_wrong,
100.0*total_correct / (total_correct+total_wrong),
first_wrong, first_wrong >= 0 ? sorted_indices[first_wrong]:-1,
vbest_snr[sorted_indices[nsort-1]]) ;
if (first_wrong >= 0) {
write_vertex_data("c1w.dat", sorted_indices[first_wrong],
c1_avg_thickness,num_class1);
write_vertex_data("c2w.dat", sorted_indices[first_wrong],
c2_avg_thickness,num_class2);
}
}
}
msec = TimerStop(&start) ;
free(total_mean);
free(c1_mean) ;
free(c2_mean) ;
free(c1_var);
free(c2_var);
seconds = nint((float)msec/1000.0f) ;
minutes = seconds / 60 ;
seconds = seconds % 60 ;
fprintf(stderr, "classification took %d minutes and %d seconds.\n",
minutes, seconds) ;
exit(0) ;
return(0) ; /* for ansi */
}
int
main(int argc, char *argv[])
{
char **av, *surf_fname, *template_fname, *out_fname, fname[STRLEN],*cp;
int ac, nargs,err, msec ;
MRI_SURFACE *mris ;
MRI_SP *mrisp_template ;
char cmdline[CMD_LINE_LEN] ;
struct timeb start ;
make_cmd_version_string
(argc, argv,
"$Id: mris_register.c,v 1.59 2011/03/02 00:04:33 nicks Exp $",
"$Name: stable5 $",
cmdline);
/* rkt: check for and handle version tag */
nargs = handle_version_option
(argc, argv,
"$Id: mris_register.c,v 1.59 2011/03/02 00:04:33 nicks Exp $",
"$Name: stable5 $");
if (nargs && argc - nargs == 1)
{
exit (0);
}
argc -= nargs;
TimerStart(&start) ;
Progname = argv[0] ;
ErrorInit(NULL, NULL, NULL) ;
DiagInit(NULL, NULL, NULL) ;
memset(&parms, 0, sizeof(parms)) ;
parms.projection = PROJECT_SPHERE ;
parms.flags |= IP_USE_CURVATURE ;
parms.tol = 0.5 ; // was 1e-0*2.5
parms.min_averages = 0 ;
parms.l_area = 0.0 ;
parms.l_parea = 0.1f ; // used to be 0.2
parms.l_dist = 5.0 ; // used to be 0.5, and before that 0.1
parms.l_corr = 1.0f ;
parms.l_nlarea = 1 ;
parms.l_pcorr = 0.0f ;
parms.niterations = 25 ;
parms.n_averages = 1024 ; // used to be 256
parms.write_iterations = 100 ;
parms.dt_increase = 1.01 /* DT_INCREASE */;
parms.dt_decrease = 0.99 /* DT_DECREASE*/ ;
parms.error_ratio = 1.03 /*ERROR_RATIO */;
parms.dt_increase = 1.0 ;
parms.dt_decrease = 1.0 ;
parms.l_external = 10000 ; /* in case manual label is specified */
parms.error_ratio = 1.1 /*ERROR_RATIO */;
parms.integration_type = INTEGRATE_ADAPTIVE ;
parms.integration_type = INTEGRATE_MOMENTUM /*INTEGRATE_LINE_MINIMIZE*/ ;
parms.integration_type = INTEGRATE_LINE_MINIMIZE ;
parms.dt = 0.9 ;
parms.momentum = 0.95 ;
parms.desired_rms_height = -1.0 ;
parms.nbhd_size = -10 ;
parms.max_nbrs = 10 ;
ac = argc ;
av = argv ;
for ( ; argc > 1 && ISOPTION(*argv[1]) ; argc--, argv++)
{
nargs = get_option(argc, argv) ;
argc -= nargs ;
argv += nargs ;
}
if (nsigmas > 0)
{
MRISsetRegistrationSigmas(sigmas, nsigmas) ;
}
parms.which_norm = which_norm ;
if (argc < 4)
{
usage_exit() ;
}
printf("%s\n", vcid) ;
printf(" %s\n",MRISurfSrcVersion());
fflush(stdout);
surf_fname = argv[1] ;
template_fname = argv[2] ;
out_fname = argv[3] ;
if (parms.base_name[0] == 0)
{
FileNameOnly(out_fname, fname) ;
cp = strchr(fname, '.') ;
if (cp)
{
strcpy(parms.base_name, cp+1) ;
}
else
{
strcpy(parms.base_name, "sphere") ;
}
}
fprintf(stderr, "reading surface from %s...\n", surf_fname) ;
mris = MRISread(surf_fname) ;
if (!mris)
ErrorExit(ERROR_NOFILE, "%s: could not read surface file %s",
Progname, surf_fname) ;
if (parms.var_smoothness)
{
parms.vsmoothness = (float *)calloc(mris->nvertices, sizeof(float)) ;
if (parms.vsmoothness == NULL)
{
ErrorExit(ERROR_NOMEMORY, "%s: could not allocate vsmoothness array",
Progname) ;
}
parms.dist_error = (float *)calloc(mris->nvertices, sizeof(float)) ;
if (parms.dist_error == NULL)
{
ErrorExit(ERROR_NOMEMORY, "%s: could not allocate dist_error array",
Progname) ;
}
parms.area_error = (float *)calloc(mris->nvertices, sizeof(float)) ;
if (parms.area_error == NULL)
{
ErrorExit(ERROR_NOMEMORY, "%s: could not allocate area_error array",
Progname) ;
}
parms.geometry_error = (float *)calloc(mris->nvertices, sizeof(float)) ;
if (parms.geometry_error == NULL)
{
ErrorExit(ERROR_NOMEMORY, "%s: could not allocate geometry_error array",
Progname) ;
}
}
MRISresetNeighborhoodSize(mris, 1) ;
if (annot_name)
{
if (MRISreadAnnotation(mris, annot_name) != NO_ERROR)
ErrorExit(ERROR_BADPARM,
"%s: could not read annot file %s",
Progname, annot_name) ;
MRISripMedialWall(mris) ;
}
MRISsaveVertexPositions(mris, TMP2_VERTICES) ;
MRISaddCommandLine(mris, cmdline) ;
if (!FZERO(dalpha) || !FZERO(dbeta) || !FZERO(dgamma))
MRISrotate(mris, mris, RADIANS(dalpha), RADIANS(dbeta),
RADIANS(dgamma)) ;
if (curvature_fname[0])
{
fprintf(stderr, "reading source curvature from %s\n",curvature_fname) ;
MRISreadCurvatureFile(mris, curvature_fname) ;
}
if (single_surf)
{
char fname[STRLEN], *cp, surf_dir[STRLEN], hemi[10] ;
MRI_SURFACE *mris_template ;
int sno, tnbrs=3 ;
FileNamePath(template_fname, surf_dir) ;
cp = strrchr(template_fname, '/') ;
if (cp == NULL) // no path - start from beginning of file name
{
cp = template_fname ;
}
cp = strchr(cp, '.') ;
if (cp == NULL)
ErrorExit(ERROR_NOFILE,
"%s: could no scan hemi from %s",
Progname, template_fname) ;
strncpy(hemi, cp-2, 2) ;
hemi[2] = 0 ;
fprintf(stderr, "reading spherical surface %s...\n", template_fname) ;
mris_template = MRISread(template_fname) ;
if (mris_template == NULL)
{
ErrorExit(ERROR_NOFILE, "") ;
}
#if 0
if (reverse_flag)
{
MRISreverse(mris_template, REVERSE_X, 1) ;
}
#endif
MRISsaveVertexPositions(mris_template, CANONICAL_VERTICES) ;
MRIScomputeMetricProperties(mris_template) ;
MRISstoreMetricProperties(mris_template) ;
if (noverlays > 0)
{
mrisp_template = MRISPalloc(scale, IMAGES_PER_SURFACE*noverlays);
for (sno = 0; sno < noverlays ; sno++)
{
sprintf(fname, "%s/../label/%s.%s", surf_dir, hemi, overlays[sno]) ;
if (MRISreadValues(mris_template, fname) != NO_ERROR)
ErrorExit(ERROR_NOFILE,
"%s: could not read overlay from %s",
Progname, fname) ;
MRIScopyValuesToCurvature(mris_template) ;
MRISaverageCurvatures(mris_template, navgs) ;
MRISnormalizeCurvature(mris_template, which_norm) ;
fprintf(stderr,
"computing parameterization for overlay %s...\n",
fname);
MRIStoParameterization(mris_template, mrisp_template, scale, sno*3) ;
MRISPsetFrameVal(mrisp_template, sno*3+1, 1.0) ;
}
}
else
{
mrisp_template = MRISPalloc(scale, PARAM_IMAGES);
for (sno = 0; sno < SURFACES ; sno++)
{
if (curvature_names[sno]) /* read in precomputed curvature file */
{
sprintf(fname, "%s/%s.%s", surf_dir, hemi, curvature_names[sno]) ;
if (MRISreadCurvatureFile(mris_template, fname) != NO_ERROR)
ErrorExit(Gerror,
"%s: could not read curvature file '%s'\n",
Progname, fname) ;
/* the two next lines were not in the original code */
MRISaverageCurvatures(mris_template, navgs) ;
MRISnormalizeCurvature(mris_template, which_norm) ;
}
else /* compute curvature of surface */
{
sprintf(fname, "%s/%s.%s", surf_dir, hemi, surface_names[sno]) ;
if (MRISreadVertexPositions(mris_template, fname) != NO_ERROR)
ErrorExit(ERROR_NOFILE,
"%s: could not read surface file %s",
Progname, fname) ;
if (tnbrs > 1)
{
MRISresetNeighborhoodSize(mris_template, tnbrs) ;
}
MRIScomputeMetricProperties(mris_template) ;
MRIScomputeSecondFundamentalForm(mris_template) ;
MRISuseMeanCurvature(mris_template) ;
MRISaverageCurvatures(mris_template, navgs) ;
MRISrestoreVertexPositions(mris_template, CANONICAL_VERTICES) ;
MRISnormalizeCurvature(mris_template, which_norm) ;
}
fprintf(stderr,
"computing parameterization for surface %s...\n",
fname);
MRIStoParameterization(mris_template, mrisp_template, scale, sno*3) ;
MRISPsetFrameVal(mrisp_template, sno*3+1, 1.0) ;
}
}
}
else
{
fprintf(stderr, "reading template parameterization from %s...\n",
template_fname) ;
mrisp_template = MRISPread(template_fname) ;
if (!mrisp_template)
ErrorExit(ERROR_NOFILE, "%s: could not open template file %s",
Progname, template_fname) ;
if (noverlays > 0)
{
if (mrisp_template->Ip->num_frame != IMAGES_PER_SURFACE*noverlays)
ErrorExit(ERROR_BADPARM,
"template frames (%d) doesn't match input (%d x %d) = %d\n",
mrisp_template->Ip->num_frame, IMAGES_PER_SURFACE,noverlays,
IMAGES_PER_SURFACE*noverlays) ;
}
}
if (use_defaults)
{
if (*IMAGEFseq_pix(mrisp_template->Ip, 0, 0, 2) <= 1.0) /* 1st time */
{
parms.l_dist = 5.0 ;
parms.l_corr = 1.0 ;
parms.l_parea = 0.2 ;
}
else /* subsequent alignments */
{
parms.l_dist = 5.0 ;
parms.l_corr = 1.0 ;
parms.l_parea = 0.2 ;
}
}
if (nbrs > 1)
{
MRISresetNeighborhoodSize(mris, nbrs) ;
}
MRISprojectOntoSphere(mris, mris, DEFAULT_RADIUS) ;
mris->status = MRIS_PARAMETERIZED_SPHERE ;
MRIScomputeMetricProperties(mris) ;
if (!FZERO(parms.l_dist))
{
MRISscaleDistances(mris, scale) ;
}
#if 0
MRISsaveVertexPositions(mris, ORIGINAL_VERTICES) ;
MRISzeroNegativeAreas(mris) ;
MRISstoreMetricProperties(mris) ;
#endif
MRISstoreMeanCurvature(mris) ; /* use curvature from file */
MRISsetOriginalFileName(orig_name) ;
if (inflated_name)
{
MRISsetInflatedFileName(inflated_name) ;
}
err = MRISreadOriginalProperties(mris, orig_name) ;
if (err != 0)
{
printf("ERROR %d from MRISreadOriginalProperties().\n",err);
exit(1);
}
if (MRISreadCanonicalCoordinates(mris, canon_name) != NO_ERROR)
ErrorExit(ERROR_BADFILE, "%s: could not read canon surface %s",
Progname, canon_name) ;
if (reverse_flag)
{
MRISreverse(mris, REVERSE_X, 1) ;
MRISsaveVertexPositions(mris, TMP_VERTICES) ;
MRISrestoreVertexPositions(mris, CANONICAL_VERTICES) ;
MRISreverse(mris, REVERSE_X, 0) ;
MRISsaveVertexPositions(mris, CANONICAL_VERTICES) ;
MRISrestoreVertexPositions(mris, TMP_VERTICES) ;
MRIScomputeMetricProperties(mris) ;
}
#if 0
MRISsaveVertexPositions
(mris, CANONICAL_VERTICES) ; // uniform spherical positions
#endif
if (starting_reg_fname)
if (MRISreadVertexPositions(mris, starting_reg_fname) != NO_ERROR)
{
exit(Gerror) ;
}
if (multiframes)
{
if (use_initial_registration)
MRISvectorRegister(mris, mrisp_template, &parms, max_passes,
min_degrees, max_degrees, nangles) ;
parms.l_corr=parms.l_pcorr=0.0f;
#if 0
parms.l_dist = 0.0 ;
parms.l_corr = 0.0 ;
parms.l_parea = 0.0 ;
parms.l_area = 0.0 ;
parms.l_parea = 0.0f ;
parms.l_dist = 0.0 ;
parms.l_corr = 0.0f ;
parms.l_nlarea = 0.0f ;
parms.l_pcorr = 0.0f ;
#endif
MRISvectorRegister(mris,
mrisp_template,
&parms,
max_passes,
min_degrees,
max_degrees,
nangles) ;
}
else
{
double l_dist = parms.l_dist ;
if (multi_scale > 0)
{
int i ;
parms.l_dist = l_dist * pow(5.0, (multi_scale-1.0)) ;
parms.flags |= IPFLAG_NOSCALE_TOL ;
parms.flags &= ~IP_USE_CURVATURE ;
for (i = 0 ; i < multi_scale ; i++)
{
printf("*************** round %d, l_dist = %2.3f **************\n", i,
parms.l_dist) ;
MRISregister(mris, mrisp_template,
&parms, max_passes,
min_degrees, max_degrees, nangles) ;
parms.flags |= IP_NO_RIGID_ALIGN ;
parms.flags &= ~IP_USE_INFLATED ;
parms.l_dist /= 5 ;
}
if (parms.nbhd_size < 0)
{
parms.nbhd_size *= -1 ;
printf("**** starting 2nd epoch, with long-range distances *****\n");
parms.l_dist = l_dist * pow(5.0, (multi_scale-2.0)) ;
for (i = 1 ; i < multi_scale ; i++)
{
printf("*********** round %d, l_dist = %2.3f *************\n", i,
parms.l_dist) ;
MRISregister(mris, mrisp_template,
&parms, max_passes,
min_degrees, max_degrees, nangles) ;
parms.l_dist /= 5 ;
}
}
printf("****** final curvature registration ***************\n") ;
if (parms.nbhd_size > 0)
{
parms.nbhd_size *= -1 ; // disable long-range stuff
}
parms.l_dist *= 5 ;
parms.flags |= (IP_USE_CURVATURE | IP_NO_SULC);
MRISregister(mris, mrisp_template,
&parms, max_passes,
min_degrees, max_degrees, nangles) ;
}
else
MRISregister(mris, mrisp_template,
&parms, max_passes,
min_degrees, max_degrees, nangles) ;
}
if (remove_negative)
{
parms.niterations = 1000 ;
MRISremoveOverlapWithSmoothing(mris,&parms) ;
}
fprintf(stderr, "writing registered surface to %s...\n", out_fname) ;
MRISwrite(mris, out_fname) ;
if (jacobian_fname)
{
MRIScomputeMetricProperties(mris) ;
compute_area_ratios(mris) ; /* will put results in v->curv */
#if 0
MRISwriteArea(mris, jacobian_fname) ;
#else
MRISwriteCurvature(mris, jacobian_fname) ;
#endif
}
msec = TimerStop(&start) ;
if (Gdiag & DIAG_SHOW)
printf("registration took %2.2f hours\n",
(float)msec/(1000.0f*60.0f*60.0f));
MRISPfree(&mrisp_template) ;
MRISfree(&mris) ;
exit(0) ;
return(0) ; /* for ansi */
}
int
main(int argc, char *argv[]) {
char **av, fname[STRLEN], *input_name, *subject_name, *cp,*hemi,
*svm_name, *surf_name, *output_subject_name ;
int ac, nargs, vno ;
int msec, minutes, seconds ;
struct timeb start ;
MRI_SURFACE *mris ;
SVM *svm ;
double classification ;
float *inputs ;
MRI_SP *mrisp ;
/* rkt: check for and handle version tag */
nargs = handle_version_option (argc, argv, "$Id: mris_svm_classify.c,v 1.6 2011/03/02 00:04:34 nicks Exp $", "$Name: $");
if (nargs && argc - nargs == 1)
exit (0);
argc -= nargs;
Progname = argv[0] ;
ErrorInit(NULL, NULL, NULL) ;
DiagInit(NULL, NULL, NULL) ;
TimerStart(&start) ;
ac = argc ;
av = argv ;
for ( ; argc > 1 && ISOPTION(*argv[1]) ; argc--, argv++) {
nargs = get_option(argc, argv) ;
argc -= nargs ;
argv += nargs ;
}
if (!strlen(subjects_dir)) /* hasn't been set on command line */
{
cp = getenv("SUBJECTS_DIR") ;
if (!cp)
ErrorExit(ERROR_BADPARM, "%s: SUBJECTS_DIR not defined in environment",
Progname);
strcpy(subjects_dir, cp) ;
}
if (argc < 7)
usage_exit(1) ;
subject_name = argv[1] ;
hemi = argv[2] ;
surf_name = argv[3] ;
input_name = argv[4] ;
output_subject_name = argv[5] ;
svm_name = argv[6] ;
printf("reading svm from %s...\n", svm_name) ;
svm = SVMread(svm_name) ;
if (!svm)
ErrorExit(ERROR_NOFILE, "%s: could not read classifier from %s",
Progname, svm_name) ;
if (log_fname != NULL)
printf("logging results to %s, true_class = %s\n",
log_fname, true_class > 0 ? svm->class1_name : svm->class2_name) ;
sprintf(fname, "%s/%s/surf/%s.%s", subjects_dir,subject_name,hemi,surf_name);
printf("reading surface from %s...\n", fname) ;
mris = MRISread(fname) ;
if (!mris)
ErrorExit(ERROR_NOFILE, "%s: could not read surface file %s for %s",
Progname, fname, subject_name) ;
MRISsaveVertexPositions(mris, CANONICAL_VERTICES) ;
if (MRISreadCurvature(mris, input_name) != NO_ERROR)
ErrorExit(ERROR_BADPARM, "%s: could not read curvature from %s", input_name) ;
if (nannotations > 0)
{
int vno, a, found ;
VERTEX *v ;
if (MRISreadAnnotation(mris, annot_name) != NO_ERROR)
ErrorExit(ERROR_NOFILE,
"%s: could not read annot file %s for subject %s",
Progname, annot_name, subject_name) ;
for (a = 0 ; a < nannotations ; a++)
{
int index ;
CTABfindName(mris->ct, anames[a], &index) ;
CTABannotationAtIndex(mris->ct, index, &annotations[a]) ;
printf("mapping annot %s to %d\n",
anames[a], annotations[a]) ;
}
// rip all vertices that don't have one of the specified annotations
for (vno = 0 ; vno < mris->nvertices ; vno++)
{
v = &mris->vertices[vno] ;
if (v->ripflag)
continue ;
found = 0 ;
for (a = 0 ; a < nannotations ; a++)
if (v->annotation == annotations[a])
found = 1 ;
if (found == 0)
v->ripflag = 1 ;
}
}
if (navgs > 0)
MRISaverageCurvatures(mris, navgs) ;
mrisp = MRIStoParameterization(mris, NULL, 1, 0) ;
MRISfree(&mris) ;
/* read in output surface */
sprintf(fname, "%s/%s/surf/%s.%s", subjects_dir,output_subject_name,hemi,surf_name);
printf("reading output surface from %s...\n", fname) ;
mris = MRISread(fname) ;
if (!mris)
ErrorExit(ERROR_NOFILE, "%s: could not read surface file %s for %s",
Progname, fname, output_subject_name) ;
MRISsaveVertexPositions(mris, CANONICAL_VERTICES) ;
MRISfromParameterization(mrisp, mris, 0) ;
if (label_name) {
area = LabelRead(output_subject_name, label_name) ;
if (!area)
ErrorExit(ERROR_NOFILE, "%s: could not read label %s", Progname,
label_name) ;
MRISmaskNotLabel(mris, area) ;
} else
area = NULL ;
if (mris->nvertices != svm->ninputs)
ErrorExit(ERROR_BADPARM, "%s: svm input (%d) does not match # of "
"surface vertices (%d)",
Progname, svm->ninputs, mris->nvertices);
inputs = (float *)calloc(mris->nvertices, sizeof(float)) ;
if (!inputs)
ErrorExit(ERROR_NOMEMORY, "%s: could not allocate %d input vector",
Progname, mris->nvertices) ;
for (vno = 0 ; vno < mris->nvertices ; vno++)
inputs[vno] = mris->vertices[vno].curv ;
classification = SVMclassify(svm, inputs) ;
printf("classification %f, class = %s",classification,
classification > 0 ? svm->class1_name : svm->class2_name) ;
if (true_class != 0)
printf(", %s", true_class*classification>0 ? "CORRECT" : "INCORRECT") ;
printf("\n") ;
if (log_fname) {
FILE *fp ;
fp = fopen(log_fname, "a") ;
if (!fp)
ErrorExit(ERROR_BADPARM, "%s: could not open log file %s", log_fname) ;
fprintf(fp, "%-30.30s %s %d %f %f\n",
subject_name, hemi, (true_class*classification)>0, classification,
true_class) ;
fclose(fp) ;
}
free(inputs) ;
MRISfree(&mris) ;
SVMfree(&svm) ;
msec = TimerStop(&start) ;
seconds = nint((float)msec/1000.0f) ;
minutes = seconds / 60 ;
seconds = seconds % 60 ;
printf("classification took %d minutes and %d seconds.\n", minutes, seconds) ;
exit(0) ;
return(0) ;
}
int main(int argc, char *argv[]) {
MRIS *mris;
char *in_orig_fname=NULL, *in_seg_fname=NULL,*out_fname=NULL;
MRI *mri_orig=NULL,*mri_seg=NULL,*mri_out=NULL;
int nargs,n;
char fname[512];
Progname=argv[0];
fprintf(stderr,"\n");
MRI_TOPOLOGY_PARMSdefault(&parms);
for ( ; argc > 1 && ISOPTION(*argv[1]) ; argc--, argv++) {
nargs = get_option(argc, argv) ;
argc -= nargs ;
argv += nargs ;
}
if (parms.tesselation_mode==-1)
parms.tesselation_mode=parms.connectivity;
if (argc<4) {
fprintf(stderr, "\nUsage: %s options input_orig_file input_segmented_file output_folder\n", Progname);
exit(1);
};
in_orig_fname=argv[argc-3];
in_seg_fname = argv[argc-2];
out_fname = argv[argc-1];
fprintf(stderr,"************************************************************"
"\nThe input orig volume is %s"
"\nThe input segmented volume is %s"
"\nThe output volume is %s"
"\nIf this is incorrect, please exit quickly the program (Ctl-C)\n",in_orig_fname,in_seg_fname,out_fname);
for (n=0;n<parms.nlabels;n++)
fprintf(stderr,"label = %d: %s \n",parms.labels[n],cma_label_to_name(parms.labels[n]));
if (parms.using_gca_maps)
fprintf(stderr,"mixing parameters: alpha=%1.3f , beta=%1.3f \n",parms.alpha,parms.beta);
else {
parms.beta=1.0f;
parms.alpha=1.0f;
}
fprintf(stderr,"connectivity = %d\n",parms.connectivity);
mri_orig=MRIread(in_orig_fname);
if (!mri_orig && parms.using_gca_maps)
Error("orig volume: orig volume could not be read\n");
mri_seg=MRIread(in_seg_fname);
if (!mri_seg)
Error("segmented volume: segmented volume could not be read\n");
//check euler characteristic of initial surface
if (parms.initial_surface_file) {
int i,j,k,val,euler,pnvertices, pnfaces, pnedges;
MRI *mri_tmp;
mri_tmp=MRIclone(mri_seg,NULL);
for (k=0;k<mri_seg->depth;k++)
for (j=0;j<mri_seg->height;j++)
for (i=0;i<mri_seg->width;i++)
for (n=0;n<parms.nlabels;n++) {
val=MRIgetVoxVal(mri_seg,i,j,k, 0);
if (val==parms.labels[n]) {
MRIsetVoxVal(mri_tmp,i,j,k,0,1);
break;
}
}
mris=MRIScreateSurfaceFromVolume(mri_tmp,1,parms.connectivity);
euler=MRIScomputeEulerNumber(mris,&pnvertices,&pnfaces,&pnedges);
fprintf(stderr,"\ninitial euler characteristic = %d, %d vertices, %d faces, %d edges"
,euler,pnvertices,pnfaces,pnedges);
MRISwrite(mris,parms.initial_surface_file);
MRISfree(&mris);
MRIfree(&mri_tmp);
}
mri_out=MRIcorrectTopology(mri_orig,mri_seg,NULL,&parms);
if (parms.nlabels == 1) {
MRI *mri_tmp ;
// turn off all voxels that are going to be on in the output
MRImask(mri_seg, mri_out, mri_seg, 1, 0) ;
/* whatever ones are left are now incorrect and should be labeled
something else
*/
resegment_erased_voxels(mri_orig, mri_seg, mri_seg, parms.labels[0]) ;
MRIreplaceValues(mri_out, mri_out, 1, parms.labels[0]) ;
mri_tmp = MRIcopy(mri_seg, NULL) ;
MRIcopyLabel(mri_out, mri_tmp, parms.labels[0]) ;
MRIfree(&mri_out) ;
mri_out = mri_tmp ;
// check_volume(mri_save, mri_out, parms.labels[0]) ;
}
MRIwrite(mri_out,out_fname);
////TEMPORARY VALIDATION STUFF //////////////////////////////////////////////////////////////////
//////////////////////////////////////////////////////////////////////////////////////////////////
/////////////////////////////////////////////////////////////////////////////////////////////////
#if 0
//validation of the algo
{
FILE *f;
MRIS *mristb[20],*mrisr;
int n,i,j,k,depth,height,width,count,count2;
int tab[20]={4,43,51,12,52,13,54,18,53,17,49,10,50,11};//,6,7,10,11,12,13,17,18,43,44,45,46,49,50,51,52,53,54};
MRI *mri_val=MRIclone(parms.mri_seg,NULL);
parms.nlabels=1;
depth=parms.mri_seg->depth;
height=parms.mri_seg->height;
width=parms.mri_seg->width;
for (n=0;n<14;n++) {
MRIfree(&parms.mri_output);
MRIfree(&parms.mri_bin);
MRIfree(&parms.mri_dist);
MRIfree(&parms.mri_fcost);
MRIfree(&parms.mri_bcost);
MRIfree(&parms.mri_fprior);
MRIfree(&parms.mri_bprior);
MRIfree(&parms.mri_labeled);
segmentationFree(&parms.F_Bseg);
segmentationFree(&parms.F_Rseg);
segmentationFree(&parms.B_Bseg);
segmentationFree(&parms.B_Rseg);
CCSfree(&parms.F_Bccs);
CCSfree(&parms.F_Rccs);
CCSfree(&parms.B_Bccs);
CCSfree(&parms.B_Rccs);
parms.labels[0]=tab[n];
MRIcorrectTopology(parms.mri_orig,parms.mri_seg,&parms.mri_output,mris
,parms.labels,parms.nblabels,parms.f_c,parms);
MRISwrite(*mris,"./tmp");
mristb[n]=MRISread("./tmp");
#if 0
count=0;
count2=0;
for (k=0;k<depth;k++)
for (j=0;j<height;j++)
for (i=0;i<width;i++) {
if (MRIvox(parms.mri_seg,i,j,k)==parms.labels[0])
count2++;
if (MRIvox(parms.mri_output,i,j,k)==1) {
MRIvox(mri_val,i,j,k)++;
if (MRIvox(parms.mri_seg,i,j,k)!=parms.labels[0])
count++;
} else if (MRIvox(parms.mri_seg,i,j,k)==parms.labels[0])
count++;
}
fprintf(stderr,"\n yeh %d %d %f \n",count,count2,100.*count/count2);
sprintf(fname,"./label%d",tab[n]);
f=fopen(fname,"a+");
fprintf(f,"\n %d %d %f ",count,count2,(float)100.*count/count2);
fclose(f);
#endif
#if 0
sprintf(fname,"./surf%d",n);
MRISwrite(mristb[n],fname);
MRISsmoothSurface2(mristb[n],5,0.5,0);
MRISsmoothSurface2(mristb[n],5,0.25,2);
MRISsmoothSurface2(mristb[n],10,0.05,5);
sprintf(fname,"./surfsmooth%d",n);
mristb[n]->type=MRIS_TRIANGULAR_SURFACE;//MRIS_BINARY_QUADRANGLE_FILE;
MRISwrite(mristb[n],fname);
MRISsetNeighborhoodSize(mristb[n],3) ;
MRIScomputeMetricProperties(mristb[n]) ;
MRIScomputeSecondFundamentalForm(mristb[n]) ;
MRISuseMeanCurvature(mristb[n]);
MRISaverageCurvatures(mristb[n],2) ;
MRISnormalizeCurvature(mristb[n], NORM_MEAN) ;
sprintf(fname,"./curv%d",n);
MRISwriteCurvature(mristb[n],fname);
#endif
}
#if 0
mrisr=MRISconcatenateQuadSurfaces(n,mristb);
mrisr->type=MRIS_TRIANGULAR_SURFACE;
MRISwrite(mrisr,"./lh.ZURFACE");
// for(k=0;k<mrisr->nvertices;k++)
// mrisr->vertices[k].curv=0.3;
//MRISnormalizeCurvature(mrisr, NORM_MEAN) ;
MRISwriteCurvature(mrisr,"./ZURFACE_CURVATURE");
for (k=0;k<mrisr->nvertices;k++)
mrisr->vertices[k].curv=mrisr->vertices[k].val;
MRISwriteCurvature(mrisr,"./ZURFACE_VAL");
#endif
n=0;
count=0;
for (k=0;k<depth;k++)
for (j=0;j<height;j++)
for (i=0;i<width;i++) {
if (MRIgetVoxVal(mri_val,i,j,k,0)>=1) {
n++;
if (MRIsetVoxVal(mri_val,i,j,k,0)>1)
count++;
}
}
// sprintf(fname,"./labeltotal");
/// f=fopen(fname,"a+");
//fprintf(f,"\n %s %d %d %f ",in_seg_fname,count,n,(float)100.*count/n);
//fclose(f);
#if 0
MRIwrite(mri_val,"/tmp/tmp");
#endif
fprintf(stderr,"\n WE HAVE %d %d %f \n",count,n,100.*count/n);
}
#endif
//////////////////////////////////////////////////////////////////////////////////
//////////////////////////////////////////////////////////////////////////////////
if (parms.final_surface_file) {
int euler,pnvertices, pnfaces, pnedges;
mris=MRIScreateSurfaceFromVolume(mri_out,1,parms.connectivity);
euler=MRIScomputeEulerNumber(mris,&pnvertices,&pnfaces,&pnedges);
fprintf(stderr,"\nfinal euler characteristic = %d, %d vertices, %d faces, %d edges"
,euler,pnvertices,pnfaces,pnedges);
sprintf(fname,"%s",parms.final_surface_file);
MRISwrite(mris,fname);
#if 0
MRISsmoothSurface(mris,7,0.2);
strcat(fname,"_smooth");
MRISwrite(mris,fname);
if (parms.fit) {
sprintf(fname,parms.surfname);
strcat(fname,"_fit");
MRISmatchSurfaceToLabel(parms.mris,parms.mri_output,1,NULL,NULL,parms.f_c);
MRISwrite(parms.mris,fname);
}
#endif
MRISfree(&mris);
}
if (mri_out)
MRIfree(&mri_out);
if (mri_orig)
MRIfree(&mri_orig);
if (mri_seg)
MRIfree(&mri_seg);
fprintf(stderr,"\n");
return NO_ERROR;
}
int main(int argc, char *argv[]) {
char **av,*subject_fname,*subjects_fname[STRLEN],fname[STRLEN],*cp,*hemi;
int ac, nargs,n , m,surface_reference,nsubjects;
MRI_SURFACE *mris;
MRI *mri,*mri_distance, *mri_orig;
int msec, minutes, seconds ;
struct timeb start;
/* rkt: check for and handle version tag */
nargs = handle_version_option
(argc, argv,
"$Id: mris_distance_to_label.cpp,v 1.8 2011/03/02 00:04:31 nicks Exp $",
"$Name: $");
if (nargs && argc - nargs == 1)
exit (0);
argc -= nargs;
Progname = argv[0] ;
ErrorInit(NULL, NULL, NULL) ;
DiagInit(NULL, NULL, NULL) ;
TimerStart(&start) ;
ac = argc ;
av = argv ;
for ( ; argc > 1 && ISOPTION(*argv[1]) ; argc--, argv++) {
nargs = get_option(argc, argv) ;
argc -= nargs ;
argv += nargs ;
}
if (!strlen(subjects_dir)) /* hasn't been set on command line */
{
cp = getenv("SUBJECTS_DIR") ;
if (!cp)
ErrorExit(ERROR_BADPARM, "%s: SUBJECTS_DIR not defined in environment",
Progname);
strcpy(subjects_dir, cp) ;
}
if (argc < 3)
usage_exit() ;
/* hemisphere information */
hemi = argv[1];
for (nsubjects=0 , n = 2 ; n < argc ; n++)
subjects_fname[nsubjects++]=argv[n];
if (nlabels==0) {
fprintf(stderr,"using default option\n");
fprintf(stderr,"computing distance maps for :\n");
fprintf(stderr," amygdala\n");
fprintf(stderr," hippocampus\n");
fprintf(stderr," pallidum\n");
fprintf(stderr," putamen\n");
fprintf(stderr," caudate\n");
fprintf(stderr," lateral ventricle\n");
// fprintf(stderr," inferior lateral ventricle\n");
fprintf(stderr," layer IV gray\n");
nlabels=8;
if (!stricmp(hemi,(char*)"rh")) { /* right hemisphere */
labels[0]=54;
labels[1]=53;
labels[2]=52;
labels[3]=51;
labels[4]=50;
labels[5]=43;
labels[6]=44;
labels[7]=-1;
} else {
labels[0]=18;
labels[1]=17;
labels[2]=13;
labels[3]=12;
labels[4]=11;
labels[5]=4;
labels[6]=5;
labels[7]=-1;
}
}
for ( m = 0 ; m < nsubjects ; m++) {
subject_fname=subjects_fname[m];
fprintf(stderr,"\n\nPROCESSING SUBJECT '%s' \n",subject_fname);
sprintf(fname,"%s/%s/surf/%s.white", subjects_dir,subject_fname,hemi);
fprintf(stderr, "reading surface from %s...\n", fname) ;
mris=MRISread(fname);
if (aseg_fname)
sprintf(fname,"%s/%s/mri/%s", subjects_dir,subject_fname,aseg_fname);
else
sprintf(fname,"%s/%s/mri/aseg.mgz", subjects_dir,subject_fname);
fprintf(stderr, "reading mri segmentation from %s...\n", fname) ;
mri=MRIread(fname);
fprintf(stderr, "allocating distance map\n") ;
mri_distance=MRIalloc(mri->width,mri->height,mri->depth,MRI_FLOAT);
for (n=0 ; n < nlabels ; n++) {
if (labels[n]>=0) {
fprintf(stderr, "generating distance map for label %d\n", labels[n]) ;
MRIextractDistanceMap(mri,mri_distance,labels[n],fdistance,mode,NULL);
fprintf(stderr,
"extracting distance values for label %d\n", labels[n]) ;
mrisExtractMRIvalues(mris,mri,mri_distance,fdistance,mode);
mrisProcessDistanceValues(mris);
surface_reference=findSurfaceReference(labels[n]);
if (surface_reference>=3 and surface_reference<=14)
sprintf(fname,"%s/%s/surf/%s.%s",
subjects_dir,subject_fname,hemi,
FRAME_FIELD_NAMES[surface_reference]);
else
sprintf(fname,"%s/%s/surf/%s.dist_%d",
subjects_dir,subject_fname,hemi,labels[n]);
fprintf(stderr,
"writing out surface distance file for label %d in %s...\n",
labels[n],fname) ;
MRISaverageCurvatures(mris,navgs);
MRISwriteCurvature(mris,fname);
} else { /* extract layer IV */
sprintf(fname,"%s/%s/surf/%s.thickness",
subjects_dir,subject_fname,hemi);
fprintf(stderr, "reading curvature from %s...\n", fname) ;
MRISreadCurvature(mris,fname);
sprintf(fname,"%s/%s/mri/T1.mgz", subjects_dir,subject_fname);
fprintf(stderr, "reading orig mri segmentation from %s...\n", fname) ;
mri_orig=MRIread(fname);
mrisExtractMidGrayValues(mris,mri_orig);
MRIfree(&mri_orig);
surface_reference=3;
sprintf(fname,"%s/%s/surf/%s.%s",
subjects_dir,subject_fname,hemi,
FRAME_FIELD_NAMES[surface_reference]);
fprintf(stderr,
"writing out surface distance file for label %d in %s...\n",
labels[n],fname) ;
MRISaverageCurvatures(mris,navgs);
MRISwriteCurvature(mris,fname);
}
}
MRIfree(&mri_distance);
MRIfree(&mri);
MRISfree(&mris);
}
msec = TimerStop(&start) ;
seconds = (int)((float)msec/1000.0f) ;
minutes = seconds / 60 ;
seconds = seconds % 60 ;
printf("mris_distance_to_label took %d minutes and %d seconds.\n",
minutes, seconds) ;
exit(0) ;
return(0) ; /* for ansi */
}
int
main(int argc, char *argv[])
{
char **av, *in_fname, *out_fname, fname[STRLEN], path[STRLEN] ;
int ac, nargs, start_t, pass ;
MRI_SURFACE *mris ;
char cmdline[CMD_LINE_LEN] ;
make_cmd_version_string
(argc, argv,
"$Id: mris_smooth.c,v 1.28 2011/03/02 00:04:34 nicks Exp $",
"$Name: stable5 $", cmdline);
/* rkt: check for and handle version tag */
nargs = handle_version_option
(argc, argv,
"$Id: mris_smooth.c,v 1.28 2011/03/02 00:04:34 nicks Exp $",
"$Name: stable5 $");
if (nargs && argc - nargs == 1)
{
exit (0);
}
argc -= nargs;
Progname = argv[0] ;
ErrorInit(NULL, NULL, NULL) ;
DiagInit(NULL, NULL, NULL) ;
ac = argc ;
av = argv ;
for ( ; argc > 1 && ISOPTION(*argv[1]) ; argc--, argv++)
{
nargs = get_option(argc, argv) ;
argc -= nargs ;
argv += nargs ;
}
if (argc < 3)
{
print_help() ;
}
in_fname = argv[1] ;
out_fname = argv[2] ;
FileNamePath(out_fname, path) ;
mris = MRISfastRead(in_fname) ;
if (!mris)
ErrorExit(ERROR_NOFILE, "%s: could not read surface file %s",
Progname, in_fname) ;
MRISaddCommandLine(mris, cmdline) ;
MRISremoveTriangleLinks(mris) ;
fprintf(stderr, "smoothing surface tessellation for %d iterations...\n",
niterations);
MRIScomputeMetricProperties(mris) ;
MRISstoreMetricProperties(mris) ;
MRISsetNeighborhoodSize(mris, nbrs) ;
#define DT 0.5
if (gaussian_norm > 0)
{
int i, done, start_avgs = gaussian_avgs, j ;
done = 0;
start_t = 0 ;
pass = 0 ;
do
{
for (i = start_t ; i < niterations+start_t ; i++)
{
MRIScomputeMetricProperties(mris) ;
MRISsaveVertexPositions(mris, TMP_VERTICES) ;
for (j = 0 ; j < 5 ; j++)
{
MRISaverageVertexPositions(mris, 2) ; // turn flat spikes into tubular ones
MRIScomputeMetricProperties(mris) ;
MRIScomputeSecondFundamentalForm(mris) ;
MRIShistoThresholdGaussianCurvatureToMarked(mris, (float)(mris->nvertices-20)/mris->nvertices) ;
}
MRISrestoreVertexPositions(mris, TMP_VERTICES) ;
MRIScomputeMetricProperties(mris) ;
MRISsmoothSurfaceNormals(mris, gaussian_avgs) ;
MRISclearMarks(mris) ;
MRISthresholdGaussianCurvatureToMarked(mris, 10, 50);
MRIScomputeSecondFundamentalForm(mris) ;
MRIShistoThresholdGaussianCurvatureToMarked(mris, (float)(mris->nvertices-20)/mris->nvertices) ;
MRISthresholdGaussianCurvatureToMarked(mris, 10, 50);
if ((write_iterations > 0) && ((i % write_iterations) == 0))
{
char fname[STRLEN] ;
sprintf(fname, "%s%04d", out_fname, i) ;
printf("writing snapshot to %s...\n", fname) ;
MRISwrite(mris, fname) ;
if (Gdiag & DIAG_WRITE)
{
MRISuseGaussianCurvature(mris) ;
sprintf(fname, "%s_K%04d", out_fname, i) ;
printf("writing curvature to %s...\n", fname) ;
MRISwriteCurvature(mris, fname) ;
sprintf(fname, "%s_marked%04d", out_fname, i) ;
printf("writing marks to %s...\n", fname) ;
MRISwriteMarked(mris, fname) ;
}
}
for (j = 0 ; j <= 5*nint(1/DT) ; j++)
{
MRISmarkedSpringTerm(mris, l_spring) ;
MRISaverageGradients(mris, gaussian_avgs) ;
MRISmomentumTimeStep(mris, momentum, DT, 1, gaussian_avgs) ;
MRISclearGradient(mris) ;
MRIScomputeMetricProperties(mris) ;
MRISsmoothSurfaceNormals(mris, gaussian_avgs) ;
{
int vno ;
VERTEX *v ;
for (vno = 0 ; vno < mris->nvertices ; vno++)
{
v = &mris->vertices[vno] ;
if (v->marked > 0)
{
v->K = 1.0/(v->marked) ;
}
else
{
v->K = 0 ;
}
}
}
}
}
MRISclearGradient(mris) ;
if (gaussian_avgs == 2)
{
if (pass++ > 4)
{
done = 1 ;
}
else
{
int num = count_big_curvatures(mris, 2) ;
printf("------------------------------------------------------\n") ;
printf("------------------------------------------------------\n") ;
printf("------------------ pass %d (num=%d) ------------------\n",
pass, num) ;
printf("------------------------------------------------------\n") ;
printf("------------------------------------------------------\n") ;
gaussian_avgs = start_avgs ;
}
}
else
{
gaussian_avgs /= 2 ;
if (done ==0)
{
printf("----------------- setting avgs to %d -----------------\n", gaussian_avgs) ;
}
}
start_t = i ;
}
while (!done) ;
#if 0
// more smoothing with principal curvatures
gaussian_avgs = start_avgs ;
printf("--------------------------------------------------------------------------\n") ;
printf("--------------------------------------------------------------------------\n") ;
printf("---------------------- starting threshold smoothing ----------------------\n") ;
printf("--------------------------------------------------------------------------\n") ;
printf("--------------------------------------------------------------------------\n") ;
do
{
for (i = start_t ; i < niterations+start_t ; i++)
{
MRIScomputeMetricProperties(mris) ;
MRIScomputeSecondFundamentalForm(mris) ;
MRISsmoothSurfaceNormals(mris, 16) ;
#define KTHRESH 1.5 // everything with kmin less than this will not move
MRISthresholdPrincipalCurvatures(mris, KTHRESH) ;
MRISspringTermWithGaussianCurvature(mris, gaussian_norm, l_spring) ;
MRISaverageGradients(mris, gaussian_avgs) ;
MRISmomentumTimeStep(mris, 0, 0.1, 1, gaussian_avgs) ;
MRISclearGradient(mris) ;
if ((write_iterations > 0) && (((i+1) % write_iterations) == 0))
{
char fname[STRLEN] ;
sprintf(fname, "%s%04d", out_fname, i+1) ;
printf("writing snapshot to %s...\n", fname) ;
MRISwrite(mris, fname) ;
if (Gdiag & DIAG_WRITE/* && DIAG_VERBOSE_ON*/)
{
MRISuseGaussianCurvature(mris) ;
sprintf(fname, "%s_K%04d", out_fname, i+1) ;
printf("writing curvature to %s...\n", fname) ;
MRISwriteCurvature(mris, fname) ;
}
}
}
MRISclearGradient(mris) ;
done = (gaussian_avgs == 2) ;
gaussian_avgs /= 2 ;
if (done ==0)
{
printf("---------------------- setting avgs to %d ----------------------\n", gaussian_avgs) ;
}
start_t = i ;
}
while (!done) ;
#endif
}
else
{
MRISaverageVertexPositions(mris, niterations) ;
}
fprintf(stderr, "smoothing complete - recomputing first and second "
"fundamental forms...\n") ;
MRIScomputeMetricProperties(mris) ;
if (rescale)
{
MRISscaleBrainArea(mris) ;
}
MRIScomputeSecondFundamentalForm(mris) ;
MRISuseMeanCurvature(mris) ;
MRISaverageCurvatures(mris, navgs) ;
if (normalize_flag)
{
MRISnormalizeCurvature(mris, which_norm) ;
}
sprintf(fname, "%s.%s", mris->hemisphere == LEFT_HEMISPHERE?"lh":"rh",
curvature_fname);
if (no_write == 0)
{
fprintf(stderr, "writing smoothed curvature to %s/%s\n", path,fname) ;
MRISwriteCurvature(mris, fname) ;
sprintf(fname, "%s.%s", mris->hemisphere == LEFT_HEMISPHERE?"lh":"rh",
area_fname);
fprintf(stderr, "writing smoothed area to %s/%s\n", path, fname) ;
MRISwriteArea(mris, fname) ;
}
if (Gdiag & DIAG_SHOW)
{
fprintf(stderr, "writing smoothed surface to %s\n", out_fname) ;
}
MRISwrite(mris, out_fname) ;
exit(0) ;
return(0) ; /* for ansi */
}
