C++ (Cpp) Locus::endの例

コード例 #1

ファイル: merge.cpp プロジェクト: galaxy001/methpipe

void
merge(istream &cpg_stream, ostream &dmr_stream, double cutoff) {
  
  bool skipped_last_cpg;
  Locus dmr;
  
  if (!read_next_significant_cpg(cpg_stream, dmr, cutoff, skipped_last_cpg))
    return;
  
  dmr.set_score(1);
  double lod_sum, mindiff_sum, unadjusted_pval;
  extract_scores(dmr.name(), lod_sum, mindiff_sum, unadjusted_pval);
  
  if (unadjusted_pval >= cutoff) {
    lod_sum = 0;
    mindiff_sum = 0;
  }
  
  Locus cpg;
  while(read_next_significant_cpg(cpg_stream, cpg, cutoff, skipped_last_cpg)) {
    double lod, mindiff;
    
    extract_scores(cpg.name(), lod, mindiff, unadjusted_pval);
    
    if (skipped_last_cpg || cpg.chrom() != dmr.chrom()) {
      update_dmr_name(dmr, lod_sum, mindiff_sum);
      
      if (lod_sum != 0) {
        dmr_stream << dmr << std::endl;
      }
      
      dmr = cpg;
      dmr.set_score(1);
      
      if (unadjusted_pval >= cutoff) {
        lod_sum = 0;
        mindiff_sum = 0;
      } else {
        lod_sum = lod;
        mindiff_sum = mindiff;
      }
      
    } else {
      dmr.set_end(cpg.end());
      dmr.set_score(dmr.score() + 1);
      
      if (unadjusted_pval < cutoff) {
        lod_sum += lod;
        mindiff_sum += mindiff;
      }
    }
    
  }
  
  update_dmr_name(dmr, lod_sum, mindiff_sum);
  dmr_stream << dmr << std::endl;
  
}