Exemplo n.º 1
0
//  ----------------------------------------------------------------------------
bool CGtfReader::x_MergeFeatureLocationSingleInterval(
    const CGff2Record& record,
    CRef< CSeq_feat > pFeature )
//  ----------------------------------------------------------------------------
{
    const CSeq_interval& gene_int = pFeature->GetLocation().GetInt();
    if ( gene_int.GetFrom() > record.SeqStart() -1 ) {
        pFeature->SetLocation().SetInt().SetFrom( record.SeqStart() );
    }
    if ( gene_int.GetTo() < record.SeqStop() - 1 ) {
        pFeature->SetLocation().SetInt().SetTo( record.SeqStop() );
    }
    if (record.Type() == "CDS"  &&  pFeature->GetData().IsCdregion()) {
        return x_FeatureTrimQualifiers(record, pFeature);
    }
    return true;
}
Exemplo n.º 2
0
CRef<CBioseq_set> CMakeCdrProds::MakeCdrProds(CRef<CSeq_annot> annot,
                                              CBioseq_Handle handle)
{
    CRef<CBioseq_set> bioseq_set(new CBioseq_set);
    if (!annot->GetData().IsFtable()) {
        // Is this the right thing to do?
        // Could throw, or could return null CRef instead.
        return bioseq_set;
    }

    list<CRef<CSeq_feat> >& ftable = annot->SetData().SetFtable();

    NON_CONST_ITERATE (list<CRef<CSeq_feat> >, feat, ftable) {
        if (!(*feat)->GetData().IsCdregion()) {
            // not interested if not a Cdregion
            continue;
        }
        if ((*feat)->IsSetProduct()) {
            // already has a product; don't make new one
            continue;
        }

        string prot;
        CSeqTranslator::Translate(**feat, handle.GetScope(), prot);
        CRef<CSeq_data> seq_data(new CSeq_data(prot,
                                               CSeq_data::e_Iupacaa));
        CRef<CSeq_inst> seq_inst(new CSeq_inst);
        seq_inst->SetSeq_data(*seq_data);
        seq_inst->SetRepr(CSeq_inst_Base::eRepr_raw);
        seq_inst->SetMol(CSeq_inst_Base::eMol_aa);
        seq_inst->SetLength(prot.size());

        CRef<CBioseq> bio_seq(new CBioseq);
        string num = NStr::NumericToString(sm_Counter.Add(1));
        // pad to five digits
        if (num.size() < 5) {
            num.insert(SIZE_TYPE(0), 5 - num.size(), '0');
        }
        string acc = "tp" + num;
        string full_acc = "lcl|" + acc;
        CRef<CSeq_id> id(new CSeq_id(full_acc));
        bio_seq->SetId().push_back(id);
        // a title
        CRef<CSeqdesc> title(new CSeqdesc);
        title->SetTitle(string("Translation product ") + acc);
        bio_seq->SetDescr().Set().push_back(title);
        // Mol_type
        CRef<CSeqdesc> mol_type(new CSeqdesc);
        mol_type->SetMol_type( eGIBB_mol_peptide);
        bio_seq->SetDescr().Set().push_back(mol_type);
        
        // set the instance
        bio_seq->SetInst(*seq_inst);
        
        // wrap this Bio_seq in an entry
        CRef<CSeq_entry> seq_entry(new CSeq_entry);
        seq_entry->SetSeq(*bio_seq);
        
        // add this entry to our Bioseq_set
        bioseq_set->SetSeq_set().push_back(seq_entry);

        // record it as product in the annot we're handed
        CRef<CSeq_loc> prod_loc(new CSeq_loc);
        prod_loc->SetWhole(*id);
        (*feat)->SetProduct(*prod_loc);
    }

    return bioseq_set;
}