/*---------------------------------------------------------------*/
int main(int argc, char *argv[]) {
int nargs, n, Ntp, nsearch, nsearch2=0;
double fwhm = 0, nresels, voxelvolume, nvoxperresel, reselvolume;
double car1mn, rar1mn,sar1mn,cfwhm,rfwhm,sfwhm, ftmp;
double car2mn, rar2mn,sar2mn;
double gmean, gstd, gmax;
FILE *fp;
sprintf(tmpstr, "S%sER%sRONT%sOR", "URF", "_F", "DO") ;
setenv(tmpstr,"1",0);
nargs = handle_version_option (argc, argv, vcid, "$Name: $");
if (nargs && argc - nargs == 1) exit (0);
argc -= nargs;
cmdline = argv2cmdline(argc,argv);
uname(&uts);
getcwd(cwd,2000);
Progname = argv[0] ;
argc --;
argv++;
ErrorInit(NULL, NULL, NULL) ;
DiagInit(NULL, NULL, NULL) ;
if (argc == 0) usage_exit();
parse_commandline(argc, argv);
check_options();
if (checkoptsonly) return(0);
if (SynthSeed < 0) SynthSeed = PDFtodSeed();
if (debug) dump_options(stdout);
// ------------- load or synthesize input ---------------------
InVals = MRIreadType(inpath,InValsType);
if(InVals == NULL) exit(1);
if(SetTR){
printf("Setting TR to %g ms\n",TR);
InVals->tr = TR;
}
if((nframes < 0 && synth) || !synth) nframes = InVals->nframes;
if(nframes < nframesmin && !SmoothOnly && !sum2file) {
printf("ERROR: nframes = %d, need at least %d\n",
nframes,nframesmin);
exit(1);
}
if (InVals->type != MRI_FLOAT) {
mritmp = MRISeqchangeType(InVals, MRI_FLOAT, 0, 0, 0);
MRIfree(&InVals);
InVals = mritmp;
}
if(synth) {
printf("Synthesizing %d frames, Seed = %d\n",nframes,SynthSeed);
mritmp = MRIcloneBySpace(InVals,MRI_FLOAT,nframes);
MRIfree(&InVals);
MRIrandn(mritmp->width, mritmp->height, mritmp->depth,
nframes, 0, 1, mritmp);
InVals = mritmp;
}
voxelvolume = InVals->xsize * InVals->ysize * InVals->zsize ;
printf("voxelvolume %g mm3\n",voxelvolume);
if(DoSqr){
printf("Computing square of input\n");
MRIsquare(InVals,NULL,InVals);
}
// -------------------- handle masking ------------------------
if (maskpath) {
printf("Loading mask %s\n",maskpath);
mask = MRIread(maskpath);
if(mask==NULL) exit(1);
if(MRIdimMismatch(mask,InVals,0)){
printf("ERROR: dimension mismatch between mask and input\n");
exit(1);
}
MRIbinarize2(mask, mask, maskthresh, 0, 1);
}
if (automask) {
RFglobalStats(InVals, NULL, &gmean, &gstd, &gmax);
maskthresh = gmean * automaskthresh;
printf("Computing mask, relative threshold = %g, gmean = %g, absthresh = %g\n",
automaskthresh,gmean,maskthresh);
mritmp = MRIframeMean(InVals,NULL);
//MRIwrite(mritmp,"fmean.mgh");
mask = MRIbinarize2(mritmp, NULL, maskthresh, 0, 1);
MRIfree(&mritmp);
}
if (mask) {
if (maskinv) {
printf("Inverting mask\n");
MRImaskInvert(mask,mask);
}
nsearch = MRInMask(mask);
if (nsearch == 0) {
printf("ERROR: no voxels found in mask\n");
exit(1);
}
// Erode the mask -----------------------------------------------
if (nerode > 0) {
printf("Eroding mask %d times\n",nerode);
for (n=0; n<nerode; n++) MRIerode(mask,mask);
nsearch2 = MRInMask(mask);
if (nsearch2 == 0) {
printf("ERROR: no voxels found in mask after eroding\n");
exit(1);
}
printf("%d voxels in mask after eroding\n",nsearch2);
}
//---- Save mask -----
if (outmaskpath) MRIwrite(mask,outmaskpath);
} else nsearch = InVals->width * InVals->height * InVals->depth;
printf("Search region is %d voxels = %lf mm3\n",nsearch,nsearch*voxelvolume);
if( (infwhm > 0 || infwhmc > 0 || infwhmr > 0 || infwhms > 0) && SmoothOnly) {
if(SaveUnmasked) mritmp = NULL;
else mritmp = mask;
if(infwhm > 0) {
printf("Smoothing input by fwhm=%lf, gstd=%lf\n",infwhm,ingstd);
MRImaskedGaussianSmooth(InVals, mritmp, ingstd, InVals);
}
if(infwhmc > 0 || infwhmr > 0 || infwhms > 0) {
printf("Smoothing input by fwhm=(%lf,%lf,%lf) gstd=(%lf,%lf,%lf)\n",
infwhmc,infwhmr,infwhms,ingstdc,ingstdr,ingstds);
MRIgaussianSmoothNI(InVals, ingstdc, ingstdr, ingstds, InVals);
}
printf("Saving to %s\n",outpath);
MRIwrite(InVals,outpath);
printf("SmoothOnly requested, so exiting now\n");
exit(0);
}
// Make a copy, if needed, prior to doing anything to data
if(outpath) InValsCopy = MRIcopy(InVals,NULL);
// Compute variance reduction factor -------------------
if(sum2file){
ftmp = MRIsum2All(InVals);
fp = fopen(sum2file,"w");
if(fp == NULL){
printf("ERROR: opening %s\n",sum2file);
exit(1);
}
printf("sum2all: %20.10lf\n",ftmp);
printf("vrf: %20.10lf\n",1/ftmp);
fprintf(fp,"%20.10lf\n",ftmp);
exit(0);
}
//------------------------ Detrend ------------------
if(DetrendOrder >= 0) {
Ntp = InVals->nframes;
printf("Polynomial detrending, order = %d\n",DetrendOrder);
X = MatrixAlloc(Ntp,DetrendOrder+1,MATRIX_REAL);
for (n=0;n<Ntp;n++) X->rptr[n+1][1] = 1.0;
ftmp = Ntp/2.0;
if (DetrendOrder >= 1)
for (n=0;n<Ntp;n++) X->rptr[n+1][2] = (n-ftmp)/ftmp;
if (DetrendOrder >= 2)
for (n=0;n<Ntp;n++) X->rptr[n+1][3] = pow((n-ftmp),2.0)/(ftmp*ftmp);
}
if(X){
printf("Detrending\n");
if (X->rows != InVals->nframes) {
printf("ERROR: dimension mismatch between X and input\n");
exit(1);
}
mritmp = fMRIdetrend(InVals,X);
if (mritmp == NULL) exit(1);
MRIfree(&InVals);
InVals = mritmp;
}
// ------------ Smooth Input BY infwhm -------------------------
if(infwhm > 0) {
printf("Smoothing input by fwhm=%lf, gstd=%lf\n",infwhm,ingstd);
MRImaskedGaussianSmooth(InVals, mask, ingstd, InVals);
}
// ------------ Smooth Input BY infwhm -------------------------
if(infwhmc > 0 || infwhmr > 0 || infwhms > 0) {
printf("Smoothing input by fwhm=(%lf,%lf,%lf) gstd=(%lf,%lf,%lf)\n",
infwhmc,infwhmr,infwhms,ingstdc,ingstdr,ingstds);
MRIgaussianSmoothNI(InVals, ingstdc, ingstdr, ingstds, InVals);
}
// ------------ Smooth Input TO fwhm -------------------------
if (tofwhm > 0) {
printf("Attempting to smooth to %g +/- %g mm fwhm (nitersmax=%d)\n",
tofwhm,tofwhmtol,tofwhmnitersmax);
mritmp = MRImaskedGaussianSmoothTo(InVals, mask, tofwhm,
tofwhmtol, tofwhmnitersmax,
&byfwhm, &tofwhmact, &tofwhmniters,
InVals);
if (mritmp == NULL) exit(1);
printf("Smoothed by %g to %g in %d iterations\n",
byfwhm,tofwhmact,tofwhmniters);
if (tofwhmfile) {
fp = fopen(tofwhmfile,"w");
if (!fp) {
printf("ERROR: opening %s\n",tofwhmfile);
exit(1);
}
fprintf(fp,"tofwhm %lf\n",tofwhm);
fprintf(fp,"tofwhmtol %lf\n",tofwhmtol);
fprintf(fp,"tofwhmact %lf\n",tofwhmact);
fprintf(fp,"byfwhm %lf\n",byfwhm);
fprintf(fp,"niters %d\n",tofwhmniters);
fprintf(fp,"nitersmax %d\n",tofwhmnitersmax);
fclose(fp);
}
}
// ------ Save smoothed/detrended ------------------------------
if(outpath) {
// This is a bit of a hack in order to be able to save undetrended
// Operates on InValsCopy, which has not been modified (requires
// smoothing twice, which is silly:).
printf("Saving to %s\n",outpath);
// Smoothed output will not be masked
if (SaveDetrended && X) {
mritmp = fMRIdetrend(InValsCopy,X);
if (mritmp == NULL) exit(1);
MRIfree(&InValsCopy);
InValsCopy = mritmp;
}
if (SaveUnmasked) mritmp = NULL;
else mritmp = mask;
if(infwhm > 0)
MRImaskedGaussianSmooth(InValsCopy, mritmp, ingstd, InValsCopy);
if(infwhmc > 0 || infwhmr > 0 || infwhms > 0)
MRIgaussianSmoothNI(InValsCopy, ingstdc, ingstdr, ingstds, InValsCopy);
if(tofwhm > 0) {
bygstd = byfwhm/sqrt(log(256.0));
MRImaskedGaussianSmooth(InValsCopy, mritmp, bygstd, InValsCopy);
}
MRIwrite(InValsCopy,outpath);
MRIfree(&InValsCopy);
}
// ----------- Compute smoothness -----------------------------
printf("Computing spatial AR1 in volume.\n");
ar1 = fMRIspatialAR1(InVals, mask, NULL);
if (ar1 == NULL) exit(1);
fMRIspatialAR1Mean(ar1, mask, &car1mn, &rar1mn, &sar1mn);
cfwhm = RFar1ToFWHM(car1mn, InVals->xsize);
rfwhm = RFar1ToFWHM(rar1mn, InVals->ysize);
sfwhm = RFar1ToFWHM(sar1mn, InVals->zsize);
fwhm = sqrt((cfwhm*cfwhm + rfwhm*rfwhm + sfwhm*sfwhm)/3.0);
printf("ar1mn = (%lf,%lf,%lf)\n",car1mn,rar1mn,sar1mn);
printf("colfwhm = %lf\n",cfwhm);
printf("rowfwhm = %lf\n",rfwhm);
printf("slicefwhm = %lf\n",sfwhm);
printf("outfwhm = %lf\n",fwhm);
reselvolume = cfwhm*rfwhm*sfwhm;
nvoxperresel = reselvolume/voxelvolume;
nresels = voxelvolume*nsearch/reselvolume;
printf("reselvolume %lf\n",reselvolume);
printf("nresels %lf\n",nresels);
printf("nvoxperresel %lf\n",nvoxperresel);
if(DoAR2){
printf("Computing spatial AR2 in volume.\n");
fMRIspatialAR2Mean(InVals, mask, &car2mn, &rar2mn, &sar2mn);
printf("ar2mn = (%lf,%lf,%lf)\n",car2mn,rar2mn,sar2mn);
}
if(ar1path) MRIwrite(ar1,ar1path);
fflush(stdout);
// ---------- Save summary file ---------------------
if(sumfile) {
fp = fopen(sumfile,"w");
if (fp == NULL) {
printf("ERROR: opening %s\n",sumfile);
exit(1);
}
dump_options(fp);
fprintf(fp,"nsearch2 %d\n",nsearch2);
fprintf(fp,"searchspace_vox %d\n",nsearch);
fprintf(fp,"searchspace_mm3 %lf\n",nsearch*voxelvolume);
fprintf(fp,"voxelvolume_mm3 %g\n",voxelvolume);
fprintf(fp,"voxelsize_mm %g %g %g\n",InVals->xsize,InVals->ysize,InVals->zsize);
fprintf(fp,"ar1mn %lf %lf %lf\n",car1mn,rar1mn,sar1mn);
fprintf(fp,"colfwhm_mm %lf\n",cfwhm);
fprintf(fp,"rowfwhm_mm %lf\n",rfwhm);
fprintf(fp,"slicefwhm_mm %lf\n",sfwhm);
fprintf(fp,"outfwhm_mm %lf\n",fwhm);
fprintf(fp,"reselvolume_mm3 %lf\n",reselvolume);
fprintf(fp,"nresels %lf\n",nresels);
fprintf(fp,"nvox_per_resel %lf\n",nvoxperresel);
fclose(fp);
}
if(datfile) {
fp = fopen(datfile,"w");
if(fp == NULL) {
printf("ERROR: opening %s\n",datfile);
exit(1);
}
fprintf(fp,"%lf\n",fwhm);
fclose(fp);
}
printf("mri_fwhm done\n");
return 0;
}
/*---------------------------------------------------------------*/
int main(int argc, char *argv[]) {
int nargs,n;
MRIS *SurfReg[100];
MRI *SrcVal, *TrgVal;
char *base;
nargs = handle_version_option (argc, argv, vcid, "$Name: $");
if (nargs && argc - nargs == 1) exit (0);
argc -= nargs;
cmdline = argv2cmdline(argc,argv);
uname(&uts);
getcwd(cwd,2000);
Progname = argv[0] ;
argc --;
argv++;
ErrorInit(NULL, NULL, NULL) ;
DiagInit(NULL, NULL, NULL) ;
if (argc == 0) usage_exit();
parse_commandline(argc, argv);
check_options();
if (checkoptsonly) return(0);
dump_options(stdout);
printf("Loading %s\n",SrcValFile);
SrcVal = MRIread(SrcValFile);
if(SrcVal==NULL) exit(1);
if(DoSynthRand) {
if (SynthSeed < 0) SynthSeed = PDFtodSeed();
printf("INFO: synthesizing, seed = %d\n",SynthSeed);
srand48(SynthSeed);
MRIrandn(SrcVal->width, SrcVal->height, SrcVal->depth,
SrcVal->nframes,0, 1, SrcVal);
}
if(DoSynthOnes != 0) {
printf("INFO: filling input with all 1s\n");
MRIconst(SrcVal->width, SrcVal->height, SrcVal->depth,
SrcVal->nframes, 1, SrcVal);
}
for(n=0; n<nsurfs; n++) {
printf("%d Loading %s\n",n+1,SurfRegFile[n]);
base = fio_basename(SurfRegFile[n],".tri");
if(strcmp(base,"ic7")==0) {
// Have to do it this way to rescale. Need to find a better more robust way.
printf(" reading as ico 7, rescaling radius to 100\n");
SurfReg[n] = ReadIcoByOrder(7, 100);
}
else
SurfReg[n] = MRISread(SurfRegFile[n]);
free(base);
if(SurfReg[n]==NULL) exit(1);
}
TrgVal = MRISapplyReg(SrcVal, SurfReg, nsurfs,ReverseMapFlag,DoJac,UseHash);
if(TrgVal == NULL) exit(1);
printf("Writing %s\n",TrgValFile);
MRIwrite(TrgVal,TrgValFile);
printf("mris_apply_reg done\n");
return 0;
}
/*---------------------------------------------------------------*/
int main(int argc, char **argv)
{
int c,r,s,f;
double val,rval;
FILE *fp;
MRI *mritmp;
Progname = argv[0] ;
argc --;
argv++;
ErrorInit(NULL, NULL, NULL) ;
DiagInit(NULL, NULL, NULL) ;
/* assign default geometry */
cdircos[0] = 1.0;
cdircos[1] = 0.0;
cdircos[2] = 0.0;
rdircos[0] = 0.0;
rdircos[1] = 1.0;
rdircos[2] = 0.0;
sdircos[0] = 0.0;
sdircos[1] = 0.0;
sdircos[2] = 1.0;
res[0] = 1.0;
res[1] = 1.0;
res[2] = 1.0;
cras[0] = 0.0;
cras[1] = 0.0;
cras[2] = 0.0;
res[3] = 2.0; /* TR */
if (argc == 0) usage_exit();
parse_commandline(argc, argv);
check_options();
dump_options(stdout);
if(tempid != NULL) {
printf("INFO: reading template header\n");
if(! DoCurv) mritemp = MRIreadHeader(tempid,tempfmtid);
else mritemp = MRIread(tempid);
if (mritemp == NULL) {
printf("ERROR: reading %s header\n",tempid);
exit(1);
}
if(NewVoxSizeSpeced){
dim[0] = round(mritemp->width*mritemp->xsize/res[0]);
dim[1] = round(mritemp->height*mritemp->ysize/res[1]);
dim[2] = round(mritemp->depth*mritemp->zsize/res[2]);
dim[3] = mritemp->nframes;
res[3] = mritemp->tr;
dimSpeced = 1;
}
if(dimSpeced){
mritmp = MRIallocSequence(dim[0],dim[1],dim[2],MRI_FLOAT,dim[3]);
MRIcopyHeader(mritemp,mritmp);
MRIfree(&mritemp);
mritemp = mritmp;
}
if(resSpeced){
mritemp->xsize = res[0];
mritemp->ysize = res[1];
mritemp->zsize = res[2];
mritemp->tr = res[3];
}
dim[0] = mritemp->width;
dim[1] = mritemp->height;
dim[2] = mritemp->depth;
if (nframes > 0) dim[3] = nframes;
else dim[3] = mritemp->nframes;
mritemp->nframes = dim[3];
}
if(mritemp) {
if(SpikeTP >= mritemp->nframes){
printf("ERROR: SpikeTP = %d >= mritemp->nframes = %d\n",
SpikeTP,mritemp->nframes);
exit(1);
}
}
printf("Synthesizing\n");
srand48(seed);
if (strcmp(pdfname,"gaussian")==0)
mri = MRIrandn(dim[0], dim[1], dim[2], dim[3], gausmean, gausstd, NULL);
else if (strcmp(pdfname,"uniform")==0)
mri = MRIdrand48(dim[0], dim[1], dim[2], dim[3], 0, 1, NULL);
else if (strcmp(pdfname,"const")==0)
mri = MRIconst(dim[0], dim[1], dim[2], dim[3], ValueA, NULL);
else if (strcmp(pdfname,"sphere")==0) {
if(voxradius < 0)
voxradius =
sqrt( pow(dim[0]/2.0,2)+pow(dim[1]/2.0,2)+pow(dim[2]/2.0,2) )/2.0;
printf("voxradius = %lf\n",voxradius);
mri = MRIsphereMask(dim[0], dim[1], dim[2], dim[3],
dim[0]/2.0, dim[1]/2.0, dim[2]/2.0,
voxradius, ValueA, NULL);
} else if (strcmp(pdfname,"delta")==0) {
mri = MRIconst(dim[0], dim[1], dim[2], dim[3], delta_off_value, NULL);
if (delta_crsf_speced == 0) {
delta_crsf[0] = dim[0]/2;
delta_crsf[1] = dim[1]/2;
delta_crsf[2] = dim[2]/2;
delta_crsf[3] = dim[3]/2;
}
printf("delta set to %g at %d %d %d %d\n",delta_value,delta_crsf[0],
delta_crsf[1],delta_crsf[2],delta_crsf[3]);
MRIFseq_vox(mri,
delta_crsf[0],
delta_crsf[1],
delta_crsf[2],
delta_crsf[3]) = delta_value;
} else if (strcmp(pdfname,"chi2")==0) {
rfs = RFspecInit(seed,NULL);
rfs->name = strcpyalloc("chi2");
rfs->params[0] = dendof;
mri = MRIconst(dim[0], dim[1], dim[2], dim[3], 0, NULL);
printf("Synthesizing chi2 with dof=%d\n",dendof);
RFsynth(mri,rfs,NULL);
} else if (strcmp(pdfname,"z")==0) {
printf("Synthesizing z \n");
rfs = RFspecInit(seed,NULL);
rfs->name = strcpyalloc("gaussian");
rfs->params[0] = 0; // mean
rfs->params[1] = 1; // std
mri = MRIconst(dim[0], dim[1], dim[2], dim[3], 0, NULL);
RFsynth(mri,rfs,NULL);
} else if (strcmp(pdfname,"t")==0) {
printf("Synthesizing t with dof=%d\n",dendof);
rfs = RFspecInit(seed,NULL);
rfs->name = strcpyalloc("t");
rfs->params[0] = dendof;
mri = MRIconst(dim[0], dim[1], dim[2], dim[3], 0, NULL);
RFsynth(mri,rfs,NULL);
} else if (strcmp(pdfname,"tr")==0) {
printf("Synthesizing t with dof=%d as ratio of z/sqrt(chi2)\n",dendof);
rfs = RFspecInit(seed,NULL);
// numerator
rfs->name = strcpyalloc("gaussian");
rfs->params[0] = 0; // mean
rfs->params[1] = 1; // std
mri = MRIconst(dim[0], dim[1], dim[2], dim[3], 0, NULL);
RFsynth(mri,rfs,NULL);
// denominator
rfs->name = strcpyalloc("chi2");
rfs->params[0] = dendof;
mri2 = MRIconst(dim[0], dim[1], dim[2], dim[3], 0, NULL);
RFsynth(mri2,rfs,NULL);
fMRIsqrt(mri2,mri2); // sqrt of chi2
mri = MRIdivide(mri,mri2,mri);
MRIscalarMul(mri, mri, sqrt(dendof)) ;
MRIfree(&mri2);
} else if (strcmp(pdfname,"F")==0) {
printf("Synthesizing F with num=%d den=%d\n",numdof,dendof);
rfs = RFspecInit(seed,NULL);
rfs->name = strcpyalloc("F");
rfs->params[0] = numdof;
rfs->params[1] = dendof;
mri = MRIconst(dim[0], dim[1], dim[2], dim[3], 0, NULL);
RFsynth(mri,rfs,NULL);
} else if (strcmp(pdfname,"Fr")==0) {
printf("Synthesizing F with num=%d den=%d as ratio of two chi2\n",
numdof,dendof);
rfs = RFspecInit(seed,NULL);
rfs->name = strcpyalloc("chi2");
// numerator
rfs->params[0] = numdof;
mri = MRIconst(dim[0], dim[1], dim[2], dim[3], 0, NULL);
RFsynth(mri,rfs,NULL);
// denominator
rfs->params[0] = dendof;
mri2 = MRIconst(dim[0], dim[1], dim[2], dim[3], 0, NULL);
RFsynth(mri2,rfs,NULL);
mri = MRIdivide(mri,mri2,mri);
MRIscalarMul(mri, mri, (double)dendof/numdof) ;
MRIfree(&mri2);
} else if (strcmp(pdfname,"voxcrs")==0) {
// three frames. 1st=col, 2nd=row, 3rd=slice
printf("Filling with vox CRS\n");
mri = MRIconst(dim[0], dim[1], dim[2], 3, 0, NULL);
for(c=0; c < mri->width; c ++){
for(r=0; r < mri->height; r ++){
for(s=0; s < mri->depth; s ++){
MRIsetVoxVal(mri,c,r,s,0,c);
MRIsetVoxVal(mri,c,r,s,1,r);
MRIsetVoxVal(mri,c,r,s,2,s);
}
}
}
} else if (strcmp(pdfname,"boundingbox")==0) {
printf("Setting bounding box \n");
if(mritemp == NULL)
mritemp = MRIconst(dim[0], dim[1], dim[2], dim[3], 0, NULL);
mri = MRIsetBoundingBox(mritemp,&boundingbox,ValueA,ValueB);
if(!mri) exit(1);
}
else if (strcmp(pdfname,"checker")==0) {
printf("Checker \n");
mri=MRIchecker(mritemp,NULL);
if(!mri) exit(1);
}
else if (strcmp(pdfname,"sliceno")==0) {
printf("SliceNo \n");
if(mritemp == NULL){
printf("ERROR: need --temp with sliceno\n");
exit(1);
}
mri=MRIsliceNo(mritemp,NULL);
if(!mri) exit(1);
}
else if (strcmp(pdfname,"indexno")==0) {
printf("IndexNo \n");
if(mritemp == NULL){
printf("ERROR: need --temp with indexno\n");
exit(1);
}
mri=MRIindexNo(mritemp,NULL);
if(!mri) exit(1);
}
else if (strcmp(pdfname,"crs")==0) {
printf("CRS \n");
if(mritemp == NULL){
printf("ERROR: need --temp with crs\n");
exit(1);
}
mri=MRIcrs(mritemp,NULL);
if(!mri) exit(1);
}
else {
printf("ERROR: pdf %s unrecognized, must be gaussian, uniform,\n"
"const, delta, checker\n", pdfname);
exit(1);
}
if (tempid != NULL) {
MRIcopyHeader(mritemp,mri);
mri->type = MRI_FLOAT;
// Override
if(nframes > 0) mri->nframes = nframes;
if(TR > 0) mri->tr = TR;
} else {
if(mri == NULL) {
usage_exit();
}
mri->xsize = res[0];
mri->ysize = res[1];
mri->zsize = res[2];
mri->tr = res[3];
mri->x_r = cdircos[0];
mri->x_a = cdircos[1];
mri->x_s = cdircos[2];
mri->y_r = rdircos[0];
mri->y_a = rdircos[1];
mri->y_s = rdircos[2];
mri->z_r = sdircos[0];
mri->z_a = sdircos[1];
mri->z_s = sdircos[2];
if(!usep0){
mri->c_r = cras[0];
mri->c_a = cras[1];
mri->c_s = cras[2];
}
else MRIp0ToCRAS(mri, p0[0], p0[1], p0[2]);
}
if (gstd > 0) {
if(!UseFFT){
printf("Smoothing\n");
MRIgaussianSmooth(mri, gstd, gmnnorm, mri); /* gmnnorm = 1 = normalize */
}
else {
printf("Smoothing with FFT \n");
mri2 = MRIcopy(mri,NULL);
mri = MRI_fft_gaussian(mri2, mri,
gstd, gmnnorm); /* gmnnorm = 1 = normalize */
}
if (rescale) {
printf("Rescaling\n");
if (strcmp(pdfname,"z")==0) RFrescale(mri,rfs,NULL,mri);
if (strcmp(pdfname,"chi2")==0) RFrescale(mri,rfs,NULL,mri);
if (strcmp(pdfname,"t")==0) RFrescale(mri,rfs,NULL,mri);
if (strcmp(pdfname,"tr")==0) RFrescale(mri,rfs,NULL,mri);
if (strcmp(pdfname,"F")==0) RFrescale(mri,rfs,NULL,mri);
if (strcmp(pdfname,"Fr")==0) RFrescale(mri,rfs,NULL,mri);
}
}
if(DoHSC){
// This multiplies each frame by a random number
// between HSCMin HSCMax to simulate heteroscedastisity
printf("Applying HSC %lf %lf\n",HSCMin,HSCMax);
for(f=0; f < mri->nframes; f++){
rval = (HSCMax-HSCMin)*drand48() + HSCMin;
if(debug) printf("%3d %lf\n",f,rval);
for(c=0; c < mri->width; c ++){
for(r=0; r < mri->height; r ++){
for(s=0; s < mri->depth; s ++){
val = MRIgetVoxVal(mri,c,r,s,f);
MRIsetVoxVal(mri,c,r,s,f,rval*val);
}
}
}
}
}
if(AddOffset) {
printf("Adding offset\n");
offset = MRIread(tempid);
if(offset == NULL) exit(1);
if(OffsetFrame == -1) OffsetFrame = nint(offset->nframes/2);
printf("Offset frame %d\n",OffsetFrame);
mritmp = fMRIframe(offset, OffsetFrame, NULL);
if(mritmp == NULL) exit(1);
MRIfree(&offset);
offset = mritmp;
fMRIaddOffset(mri, offset, NULL, mri);
}
if(SpikeTP > 0){
printf("Spiking time point %d\n",SpikeTP);
for(c=0; c < mri->width; c ++){
for(r=0; r < mri->height; r ++){
for(s=0; s < mri->depth; s ++){
MRIsetVoxVal(mri,c,r,s,SpikeTP,1e9);
}
}
}
}
if(DoAbs){
printf("Computing absolute value\n");
MRIabs(mri,mri);
}
if(!NoOutput){
printf("Saving\n");
if(!DoCurv) MRIwriteAnyFormat(mri,volid,volfmt,-1,NULL);
else {
printf("Saving in curv format\n");
MRIScopyMRI(surf, mri, 0, "curv");
MRISwriteCurvature(surf,volid);
}
}
if(sum2file){
val = MRIsum2All(mri);
fp = fopen(sum2file,"w");
if(fp == NULL){
printf("ERROR: opening %s\n",sum2file);
exit(1);
}
printf("sum2all: %20.10lf\n",val);
printf("vrf: %20.10lf\n",1/val);
fprintf(fp,"%20.10lf\n",val);
}
return(0);
}
/*---------------------------------------------------------------*/
MRI *fMRIhsynth(MRI *res, MRI *mask, int DoTNorm)
{
int c,r,s,f,nvox;
double val;
MRI *hsynth, *tvar=NULL;
double *svar, svarsum, tstdvox;
// Compute temporal variance at each voxel
if(DoTNorm) tvar = fMRIcovariance(res, 0, -1, mask, NULL);
// Compute spatial variance at each frame
svar = (double *) calloc(res->nframes,sizeof(double));
svarsum = 0;
for (f=0; f < res->nframes; f++) {
svar[f] = 0;
nvox = 0;
for (c=0; c < res->width; c++) {
for (r=0; r < res->height; r++) {
for (s=0; s < res->depth; s++) {
if(mask && MRIgetVoxVal(mask,c,r,s,0) == 0) continue;
val = MRIgetVoxVal(res,c,r,s,f);
if(DoTNorm){
tstdvox = sqrt(MRIgetVoxVal(tvar,c,r,s,0));
val /= tstdvox;
}
svar[f] += (val*val);
nvox ++;
}
}
}
svar[f] /= nvox;
svarsum += svar[f];
}
for (f=0; f < res->nframes; f++) svar[f] /= (svarsum/res->nframes);
for (f=0; f < res->nframes; f++) printf("%2d %g\n",f,svar[f]);
// Synth noise that is both spatially and temporally white and gaussian
hsynth = MRIrandn(res->width, res->height, res->depth, res->nframes, 0, 1, NULL);
MRIcopyHeader(res,hsynth);
// Scale by frame. Noise is still independent across
// space and time, but it is no longer homogeneous.
for (f=0; f < res->nframes; f++) {
for (c=0; c < res->width; c++) {
for (r=0; r < res->height; r++) {
for (s=0; s < res->depth; s++) {
if(mask && MRIgetVoxVal(mask,c,r,s,0) == 0) {
MRIsetVoxVal(hsynth,c,r,s,f,0);
continue;
}
val = MRIgetVoxVal(hsynth,c,r,s,f);
val *= sqrt(svar[f]);
MRIsetVoxVal(hsynth,c,r,s,f,val);
}
}
}
}
free(svar);
if(DoTNorm) MRIfree(&tvar);
return(hsynth);
}
/*---------------------------------------------------------------*/
int main(int argc, char *argv[]) {
int nargs,n,err;
MRIS *SurfReg[100];
MRI *SrcVal, *TrgVal;
char *base;
COLOR_TABLE *ctab=NULL;
nargs = handle_version_option (argc, argv, vcid, "$Name: $");
if (nargs && argc - nargs == 1) exit (0);
argc -= nargs;
cmdline = argv2cmdline(argc,argv);
uname(&uts);
getcwd(cwd,2000);
Progname = argv[0] ;
argc --;
argv++;
ErrorInit(NULL, NULL, NULL) ;
DiagInit(NULL, NULL, NULL) ;
if (argc == 0) usage_exit();
parse_commandline(argc, argv);
check_options();
if (checkoptsonly) return(0);
dump_options(stdout);
// Load in surface registrations
for(n=0; n<nsurfs;n++){
printf("%d Loading %s\n",n+1,SurfRegFile[n]);
base = fio_basename(SurfRegFile[n],".tri");
if(strcmp(base,"ic7")==0){
// Have to do it this way to rescale. Need to find a better more robust way.
printf(" reading as ico 7, rescaling radius to 100\n");
SurfReg[n] = ReadIcoByOrder(7, 100);
}
else
SurfReg[n] = MRISread(SurfRegFile[n]);
free(base);
if(SurfReg[n]==NULL) exit(1);
}
// Load in source data
SrcVal = NULL;
if(DoSynthRand) {
if (SynthSeed < 0) SynthSeed = PDFtodSeed();
printf("INFO: synthesizing, seed = %d\n",SynthSeed);
srand48(SynthSeed);
MRIrandn(SrcVal->width, SrcVal->height, SrcVal->depth,
SrcVal->nframes,0, 1, SrcVal);
}
else if(DoSynthOnes != 0) {
printf("INFO: filling input with all 1s\n");
MRIconst(SrcVal->width, SrcVal->height, SrcVal->depth,
SrcVal->nframes, 1, SrcVal);
}
else if(AnnotFile) {
printf("Loading annotation %s\n",AnnotFile);
err = MRISreadAnnotation(SurfReg[0], AnnotFile);
if(err) exit(1);
SrcVal = MRISannotIndex2Seg(SurfReg[0]);
ctab = CTABdeepCopy(SurfReg[0]->ct);
}
else if(LabelFile) {
LABEL *srclabel;
printf("Loading label %s\n",LabelFile);
srclabel = LabelRead(NULL, LabelFile);
if(srclabel == NULL) exit(1);
SrcVal = MRISlabel2Mask(SurfReg[0],srclabel,NULL);
printf(" %d points in input label\n",srclabel->n_points);
LabelFree(&srclabel);
}
else {
printf("Loading %s\n",SrcValFile);
SrcVal = MRIread(SrcValFile);
if(SrcVal==NULL) exit(1);
}
// Apply registration to source
TrgVal = MRISapplyReg(SrcVal, SurfReg, nsurfs, ReverseMapFlag, DoJac, UseHash);
if(TrgVal == NULL) exit(1);
// Save output
if(AnnotFile){
printf("Converting to target annot\n");
err = MRISseg2annot(SurfReg[nsurfs-1],TrgVal,ctab);
if(err) exit(1);
printf("Writing %s\n",TrgValFile);
MRISwriteAnnotation(SurfReg[nsurfs-1], TrgValFile);
}
else if(LabelFile){
LABEL *label;
label = MRISmask2Label(SurfReg[nsurfs-1], TrgVal, 0, 10e-5);
printf(" %d points in output label\n",label->n_points);
err = LabelWrite(label,TrgValFile);
if(err){
printf("ERROR: writing label file %s\n",TrgValFile);
exit(1);
}
LabelFree(&label);
}
else{
printf("Writing %s\n",TrgValFile);
MRIwrite(TrgVal,TrgValFile);
}
printf("mris_apply_reg done\n");
return 0;
}
