Пример #1
0
int main(int argc, char **argv) {
    int a = 1;
    int format = TT_ANY;
    mFILE *ofp = mstdout();
    char *name = NULL, *oname = NULL;
    int output_conf = 0;

    read_sections(READ_BASES);

    while (a < argc) {
        if (strcasecmp(argv[a], "-abi") == 0)
            format = TT_ABI;

        else if (strcasecmp(argv[a], "-alf") == 0)
            format = TT_ALF;

        else if (strcasecmp(argv[a], "-scf") == 0)
            format = TT_SCF;

        else if (strcasecmp(argv[a], "-pln") == 0)
            format = TT_PLN;

        else if (strcasecmp(argv[a], "-name") == 0) {
            if (a == argc)
                usage();

            name = argv[++a];

        } else if (strcasecmp(argv[a], "-output") == 0) {
            if (a == argc)
                usage();

            ofp = mfopen(oname = argv[++a], "wb");
            if (NULL == ofp) {
                perror(argv[a]);
                return 1;
            }

        } else if (strcasecmp(argv[a], "-conf") == 0) {
            output_conf = 1;

        } else if (argv[a][0] == '-')
            usage();
        else
            break;

        a++;
    }

    if (a+1 != argc)
        usage();

    if (!name)
        name = oname;
    if (!name)
        name = argv[a];

    return convert(argv[a], format, ofp, name, output_conf);
}
Пример #2
0
bool Vfile::read(string filename) {
	// open the file
	ifstream v(filename.c_str());
	if (!v) {
		cout << "Couldn't open file " << filename << " for reading" << endl;
		return false;
	}

	// read the static portions
	read_ok = true;
	read_header(v);
	read_sections(v);

	// check if global bodies were found and datatype is double
	if (bodies.GroupID==-1) { cout << "==============================" << endl; read_ok = false; return read_ok; }
	assert(bodies.Type==6);

	read_dynamics(v);
	v.close();
	return read_ok;

}
Пример #3
0
int main(int argc, char *argv[])
{
	if (argc != 3)
		fail("usage: unself in.self out.elf");

	self = mmap_file(argv[1]);

	read_header();
	read_sections();

	if (key_ver != 0x8000)
		self_decrypt();

	out = fopen(argv[2], "w+");

	write_elf();
	check_elf();

	fclose(out);

	return 0;
}
Пример #4
0
/*
 * Read the ALF format sequence from FILE *fp into a Read structure.
 * All printing characters (as defined by ANSII C `isprint')
 * are accepted, but `N's are translated to `-'s. In this respect we
 * are adhering (more or less) to the CSET_DEFAULT uncertainty code set.
 * 
 * Returns:
 *   Read *	- Success, the Read structure read.
 *   NULLRead	- Failure.
 */
Read *fread_alf(FILE *fp) {
    Read *read = NULLRead;
    int i;
    int numPoints;
    int sections = read_sections(0);
    
    uint_4 data_size;
    uint_4 dataO;
    uint_4 header_size=396; /* size of the header of the processed data
			       section */
    uint_2 actBaseDataSize; /* actual number of bytes of data of information
			       containing the base and basePos information */
    int num_points;         /* keeps track of the actual number of points,
			       rather than the early guess of numPoints */

    off_t indexO;           /* File offset where the index is */
    uint_4 baseO;           /* File offset where the bases are stored */
    
    
    /*
     * RMD lots of changes below here until end of data reading section
     * Some are cosmetic.
     * getIndexEntry calls in front of where they were needed, and made
     * There is a substantive change to the inner loop of the sequence
     * reading section.  This now uses fscanf - much less rigid than the
     * previous scheme.  Note that it reads bp as a float.  This is because
     * it is a float in multiple trace data files! (bizarre Pharmacia
     * programming!).
     */
    
    
    /*************************************************************
     * Read the various file offsets
     *************************************************************/

    /* indexO is the offset of the index.
     * Or I could look for the first label, starting 'ALF'
     * if I used 512 then none of the entries are on long 
     * word boundaries
     */
    indexO = 522;
    
    /* offset in file of first base of sequence */
    if (! (getIndexEntryLW(fp,indexO,BaseEntryLabel,12,&baseO)) )
	goto bail_out;
    
    /* actual size of region containing this data */
    if (! (getIndexEntryW(fp,indexO,BaseEntryLabel,10,&actBaseDataSize)) )
	goto bail_out;
    
    /* Look for Processed data first. If we fail to find it, then look for
     * the Raw data (same format).
     */

    /* offset in file to start of processed data segment - there 
     * is then a header of size header_size (currently 396)
     */
    if (! (getIndexEntryLW(fp,indexO,DataEntryLabel,12,&dataO)) ) {
	if (! (getIndexEntryLW(fp,indexO,RawDataEntryLabel,12,&dataO)) )
	    goto bail_out;

	/* actual size of region containing this data */
	if (! (getIndexEntryLW(fp,indexO,RawDataEntryLabel,10,&data_size)) )
	    goto bail_out;
    } else {
	/* actual size of region containing this data */
	if (! (getIndexEntryLW(fp,indexO,DataEntryLabel,10,&data_size)) )
	    goto bail_out;
    }
    
    /* Because each trace value is stored in a 2 byte
     * integer, thus to store A C G T information
     * it takes 8 bytes.  So subtract off the header and
     * divide by 8
     */
    numPoints = (int)((data_size - header_size)/ 8); 
    
    /* Allocate the sequence */
    if (NULLRead == (read = read_allocate(numPoints, BASELIMIT)))
	goto bail_out;
    
    /*************************************************************
     * Read the bases information
     *************************************************************/
    if (sections & READ_BASES) {
	/* new locals introduced by LFW and/or RMD for the ALF */
	int numBases;	/* number of nucleotides read in */
	float bp;
	char ch;

	if (!(fseek(fp, (off_t)baseO, 0) == 0))
	    goto bail_out;
	
	for (numBases = 0; (unsigned)ftell(fp) < baseO+(unsigned short)actBaseDataSize
	                   && numBases<BASELIMIT;) {
	    char line[200];

	    fgets(line, (int)sizeof(line), fp);
	    sscanf(line, "%c %*d %f", &ch, &bp);
	    
	    /* we convert ch to Staden format here */
	    switch (ch) {
	    case 'A':
	    case 'C':
	    case 'G':
	    case 'T':
		break;
	    default:
		ch = '-';
/*
		if (isupper(ch))
		    ch = '-';
		else
		    ch = '\0';
*/
	    }
	    
	    if (ch) {
		read->base[numBases]    = ch;
		read->prob_A[numBases]	= 0;
		read->prob_C[numBases]	= 0;
		read->prob_G[numBases]	= 0;
		read->prob_T[numBases]	= 0;
		read->basePos[numBases] = bp;
		++numBases;
	    }
	}
	read->base[numBases] = 0;
	
	read->NBases  = numBases;
    }
    
    /*************************************************************
     * Read the trace information
     *************************************************************/
    
    if (sections & READ_SAMPLES) {
	
	/*
	 * Traces are stored as 2 byte integers in records in the order of
	 * A C G T A C G T ...
	 */
	
	if (fseek(fp, (off_t)(dataO+header_size), 0) != 0) 
	    goto bail_out;
	
	num_points = 0;
	
	for (i=0; i < read->NPoints; i++) {
	    if (!le_read_int_2(fp, &(read->traceA[i])))
		goto bail_out;
	    if (read->maxTraceVal < read->traceA[i])
		read->maxTraceVal = read->traceA[i];
	    
	    if (!le_read_int_2(fp, &(read->traceC[i])))
		goto bail_out;
	    if (read->maxTraceVal < read->traceC[i])
		read->maxTraceVal = read->traceC[i];
	    
	    if (!le_read_int_2(fp, &(read->traceG[i])))
		goto bail_out;
	    if (read->maxTraceVal < read->traceG[i])
		read->maxTraceVal = read->traceG[i];
	    
	    if (!le_read_int_2(fp, &(read->traceT[i])))
		goto bail_out;
	    if (read->maxTraceVal < read->traceT[i])
		read->maxTraceVal = read->traceT[i];
	    
	    if (read->traceA[i]==0 && read->traceT[i]==0 &&
		read->traceC[i]==0 && read->traceG[i]==0 &&
		i > (numPoints-64))
		break;
	    
	    num_points++;
	}
    }
    
    /* SUCCESS */

    read->format = TT_ALF;
    return(read);

    /* FAILURE */
 bail_out:
    if (read)
	read_deallocate(read);

    return NULLRead;
}
Пример #5
0
int main(int argc, char **argv) {
    Read *r = NULL;
    char *directory = NULL;
    char *ident, *value;
    int ident_len, value_len;
    int i, j, found;
    int *found_args = NULL;
    char **FileList = NULL;
    char trace_filename[FILENAME_MAX]="";
    int num_traces, trace_iter, files_read = 0;
    char *str;

    if(argc != 2)
      usage();

    directory = argv[1];
    
    // Get a list of all chromatogram files in the directory
    num_traces = GetFileList(&FileList, directory);
    if(num_traces == 0){
      fprintf(stderr,"* Path %d yielded 0 files...exiting\n", num_traces);
      exit(2);
    }


  /* step through all the sequences */
  for (trace_iter = 0; trace_iter < num_traces; trace_iter++){

    if(r){
      read_deallocate(r);
    }
    //Get the file name from the iterator.
    sprintf(trace_filename, "%s/%s",directory, FileList[trace_iter]);

    /* Read the file */
    read_sections(READ_COMMENTS);
    if (NULL == (r = read_reading(trace_filename, TT_ANY))) {
      continue;  // don't worry about it
    }
    files_read++;

    if (!r->info)
	return 1;
    
    for(str = strtok(r->info,"\n"); str != NULL;       str = strtok(NULL,"\n")){
      char *name;
      char *value;
      int items = 0;
      char *start,*end;

      name = str;
      value = strchr(name,'=');
      *value = '\0'; // skip over the '='
      value++;
         
      if(!strcmp(name,"RUND")){
	start = value;
	end = strstr(value," - ");
	*end = '\0';   // terminate the start string
	end += 3;      // skip over the " - "
	fprintf(stdout,"%s.RUND=start=%s,end=%s\n", FileList[trace_iter], start,end);
      }else if(! strcmp(name,"DATE")){
	start = value;
	end = strstr(value," to ");
	*end = '\0'; // terminate the start string
	end += 4;    // skip over the " to "
	fprintf(stdout,"%s.DATE=start=%s,end=%s\n", FileList[trace_iter],start,end);
      }else{
	fprintf(stdout,"%s.%s=%s\n", FileList[trace_iter],name, value);
      }

    }
    
  }
  return (files_read == 0);  // is zero, unless we read nothing.
}
Пример #6
0
/*
 * fread_ztr
 *
 * Reads a ZTR file from 'fp'. This checks for the correct magic number and
 * major version number, but not minor version number.
 *
 * FIXME: Add automatic uncompression?
 *
 * Arguments:
 *	fp		A readable FILE pointer
 *
 * Returns:
 *	Success: Pointer to a ztr_t structure (malloced)
 *	Failure: NULL
 */
ztr_t *fread_ztr(FILE *fp) {
    ztr_t *ztr;
    ztr_chunk_t *chunk;
    int sections = read_sections(0);
    
    /* Allocate */
    if (NULL == (ztr = new_ztr()))
	return NULL;

    /* Read the header */
    if (-1 == ztr_read_header(fp, &ztr->header))
	return NULL;

    /* Check magic number and version */
    if (memcmp(ztr->header.magic, ZTR_MAGIC, 8) != 0)
	return NULL;

    if (ztr->header.version_major != ZTR_VERSION_MAJOR)
	return NULL;

    /* Load chunks */
    while ((chunk = ztr_read_chunk_hdr(fp))) {
	/*
	char str[5];

	fprintf(stderr, "Read chunk %.4s %08x length %d\n",
		ZTR_BE2STR(chunk->type, str), chunk->type, chunk->dlength);
	*/
	switch(chunk->type) {
	case ZTR_TYPE_HEADER:
	    /* End of file */
	    return ztr;

	case ZTR_TYPE_SAMP:
	case ZTR_TYPE_SMP4:
	    if (! (sections & READ_SAMPLES)) {
		fseek(fp, chunk->dlength, SEEK_CUR);
		xfree(chunk);
		continue;
	    }
	    break;

          
	case ZTR_TYPE_BASE:
	case ZTR_TYPE_BPOS:
	case ZTR_TYPE_CNF4:
	case ZTR_TYPE_CNF1:
	case ZTR_TYPE_CSID:
	    if (! (sections & READ_BASES)) {
		fseek(fp, chunk->dlength, SEEK_CUR);
		xfree(chunk);
		continue;
	    }
	    break;

	case ZTR_TYPE_TEXT:
	    if (! (sections & READ_COMMENTS)) {
		fseek(fp, chunk->dlength, SEEK_CUR);
		xfree(chunk);
		continue;
	    }
	    break;

	case ZTR_TYPE_CLIP:
	case ZTR_TYPE_FLWO:
	case ZTR_TYPE_FLWC:
	    break;

	    /*
	default:
	    fprintf(stderr, "Unknown chunk type '%s': skipping\n",
		    ZTR_BE2STR(chunk->type,str));
	    fseek(fp, chunk->dlength, SEEK_CUR);
	    xfree(chunk);
	    continue;
	    */
	}

	chunk->ztr_owns = 1;
	chunk->data = (char *)xmalloc(chunk->dlength);
	if (chunk->dlength != fread(chunk->data, 1, chunk->dlength, fp)) {
	    delete_ztr(ztr);
	    return NULL;
	}
            
	ztr->nchunks++;
	ztr->chunk = (ztr_chunk_t *)xrealloc(ztr->chunk, ztr->nchunks *
					     sizeof(ztr_chunk_t));
	memcpy(&ztr->chunk[ztr->nchunks-1], chunk, sizeof(*chunk));
	xfree(chunk);
    }

    return ztr;
}
Пример #7
0
/*
 * Read the SCF format sequence from FILE *fp into a 'scf' structure.
 * A NULL result indicates failure.
 */
Scf *fread_scf(FILE *fp) {
    Scf *scf;
    Header h;
    int err;
    float scf_version;
    int sections = read_sections(0);

    /* Read header */
    if (read_scf_header(fp, &h) == -1) {
	return NULL;
    }

    /* Allocate memory */
    if (NULL == (scf = scf_allocate(h.samples, h.sample_size,
				    h.bases, h.comments_size,
				    h.private_size))) 
	return NULL;

    /* fake things for older style SCF -- SD */
    if (h.sample_size != 1 && h.sample_size != 2) h.sample_size = 1;

    scf_version = scf_version_str2float(h.version);

    memcpy(&scf->header, &h, sizeof(Header));

    if (sections & READ_SAMPLES) {
	/* Read samples */
	if (fseek(fp, (off_t)h.samples_offset, 0 /* SEEK_SET */) != 0) {
	    scf_deallocate(scf);
	    return NULL;
	}

	if ( 2.9 > scf_version ) {

	    if (h.sample_size == 1) {
		err= read_scf_samples1(fp, scf->samples.samples1, h.samples);
	    }
	    else {
		err= read_scf_samples2(fp, scf->samples.samples2, h.samples);
	    }
	}
	else {

	    if (h.sample_size == 1) {
		err= read_scf_samples31(fp, scf->samples.samples1, h.samples);
	    } 
	    else {
		err= read_scf_samples32(fp, scf->samples.samples2, h.samples);
	    }
	}
	if (-1 == err) {
	    scf_deallocate(scf);
	    return NULL;
	}
    }

    if (sections & READ_BASES) {
	/* Read bases */
	if (fseek(fp, (off_t)h.bases_offset, 0 /* SEEK_SET */) != 0) {
	    scf_deallocate(scf);
	    return NULL;
	}

	if ( 2.9 > scf_version ) {

	    if (-1 == read_scf_bases(fp, scf->bases, h.bases)) {
		scf_deallocate(scf);
		return NULL;
	    }
	}
	else {
	
	    if (-1 == read_scf_bases3(fp, scf->bases, h.bases)) {
		scf_deallocate(scf);
		return NULL;
	    }
	}
    }

    if (sections & READ_COMMENTS) {
	/* Read comments */
	if (scf->comments) {
	    if (fseek(fp,(off_t)(h.comments_offset), 0) != 0
		|| -1 == read_scf_comment(fp, scf->comments,
					  h.comments_size)) {
		/*
		 * Was: "scf_deallocate(scf); return NULL;".
		 * We now simply clear the comments and gracefully continue.
		 */
		fprintf(stderr, "Warning: SCF file had invalid comment field\n");
		xfree(scf->comments);
		scf->comments = NULL;
	    } else {
		scf->comments[h.comments_size] = '\0';
	    }
	}
    }

    /* Read private data */
    if (h.private_size) {
	if (-1 == fseek(fp, (off_t)(h.private_offset), 0) ||
	    h.private_size != fread(scf->private_data, 1, h.private_size, fp)){
	    scf_deallocate(scf);
	    return NULL;
	}
    }

    return scf;
}
Пример #8
0
/*
 * Translates an Scf structure into a Read structure.
 * The Scf structure is left unchanged.
 *
 * Returns:
 *    A pointer to an allocated Read structure upon success.
 *    NULLRead upon failure.
 */
Read *scf2read(Scf *scf) {
    Read *read;
    register int i, i_end;
    TRACE max_val = 0;
    int sections = read_sections(0);
    int nsamples = 0;
    int nbases = 0;

    /* allocate */
    if (sections & READ_SAMPLES)
	nsamples = scf->header.samples;
    if (sections & READ_BASES)
	nbases = scf->header.bases;
    read = read_allocate(nsamples, nbases);

    if (NULLRead == read)
	return NULLRead;

    if (sections & READ_SAMPLES) {
	/* copy the samples */
	i_end = scf->header.samples;
	read->NPoints = i_end;
	
	if (scf->header.sample_size == 1) {
	    for (i = 0; i < i_end; i++) {
		read->traceA[i] = scf->samples.samples1[i].sample_A;
		read->traceC[i] = scf->samples.samples1[i].sample_C;
		read->traceG[i] = scf->samples.samples1[i].sample_G;
		read->traceT[i] = scf->samples.samples1[i].sample_T;
		
		if (read->traceA[i] > max_val) max_val = read->traceA[i];
		if (read->traceC[i] > max_val) max_val = read->traceC[i];
		if (read->traceG[i] > max_val) max_val = read->traceG[i];
		if (read->traceT[i] > max_val) max_val = read->traceT[i];
	    }
	} else { /* sample_size == 2 */
	    for (i = 0; i < i_end; i++) {
		read->traceA[i] = scf->samples.samples2[i].sample_A;
		read->traceC[i] = scf->samples.samples2[i].sample_C;
		read->traceG[i] = scf->samples.samples2[i].sample_G;
		read->traceT[i] = scf->samples.samples2[i].sample_T;
		
		if (read->traceA[i] > max_val) max_val = read->traceA[i];
		if (read->traceC[i] > max_val) max_val = read->traceC[i];
		if (read->traceG[i] > max_val) max_val = read->traceG[i];
		if (read->traceT[i] > max_val) max_val = read->traceT[i];
	    }
	}
	
	read->maxTraceVal = max_val;
    }
    
    if (sections & READ_BASES) {
	/* copy the bases */
	i_end = scf->header.bases;
	read->NBases = i_end;

	for (i = 0; i < i_end; i++) {
	    read->basePos[i] = scf->bases[i].peak_index;
	    read->prob_A[i]  = scf->bases[i].prob_A;
	    read->prob_C[i]  = scf->bases[i].prob_C;
	    read->prob_G[i]  = scf->bases[i].prob_G;
	    read->prob_T[i]  = scf->bases[i].prob_T;
	    read->base[i]    = scf->bases[i].base;
	}
	read->base[i] = 0;
    }
    
    if (sections & READ_COMMENTS) {
	/* allocate and copy the comments */
	if (scf->header.comments_size > 0 && scf->comments) {
	    read->info = (char *)xmalloc(scf->header.comments_size+1);
	    if (NULL == read->info) {
		read_deallocate(read);
		return NULLRead;
	    }

	    memcpy(read->info, scf->comments, scf->header.comments_size);
	    read->info[scf->header.comments_size] = '\0';
	}
    }

    /* other bits and pieces */
    read->leftCutoff = scf->header.bases_left_clip;
    read->rightCutoff = read->NBases - scf->header.bases_right_clip + 1;
    read->format = TT_SCF;

    return read;
}
Пример #9
0
/*
 * Allocate a new sequence, with the given sizes.
 * Returns:
 *   "Read *" for success
 *   "NULLRead" for failure
 */
Read *read_allocate(int num_points, int num_bases) {
    Read *seq = NULLRead;

    int sections = read_sections(0);

    /* Allocate the body of the sequence */
    if ((seq = (Read *)xmalloc(sizeof(Read))) == NULL)
	return(NULLRead);

    seq->NPoints = num_points;
    seq->NBases  = num_bases;

    /*   
     * Initialise the body, all pointers are set to NULL so we can
     * happily call `read_deallocate()`.
     */
    seq->leftCutoff  = 0;
    seq->rightCutoff = 0;
    seq->maxTraceVal = 0;
    seq->baseline = 0;

    seq->traceC    = NULL;
    seq->traceA    = NULL;
    seq->traceG    = NULL;
    seq->traceT    = NULL;

    seq->base      = NULL;
    seq->basePos   = NULL;

    seq->info = NULL;
    seq->format = TT_ANY;
    seq->trace_name = NULL;

    seq->prob_A = NULL;
    seq->prob_C = NULL;
    seq->prob_G = NULL;
    seq->prob_T = NULL;

    seq->orig_trace_format = TT_ANY;
    seq->orig_trace = NULL;
    seq->orig_trace_free = NULL;

    seq->ident = NULL;

    /* Allocate space for the bases - 1 extra for the ->base field so
     * that we can treat it as a NULL terminated string.
     */
    if (sections & READ_BASES &&
	(((seq->base	  = (char *)xcalloc(num_bases+1,1))   == NULL) ||
	 ((seq->basePos   = (uint_2 *)xcalloc(num_bases+1,2)) == NULL) ||
	 ((seq->prob_A    = (char *)xcalloc(num_bases+1,1))   == NULL) ||
	 ((seq->prob_C    = (char *)xcalloc(num_bases+1,1))   == NULL) ||
	 ((seq->prob_G    = (char *)xcalloc(num_bases+1,1))   == NULL) ||
	 ((seq->prob_T    = (char *)xcalloc(num_bases+1,1))   == NULL))
	)
    {
	read_deallocate(seq);
	return NULLRead;
    }

    if (sections & READ_SAMPLES &&
	(((seq->traceC   =(TRACE *)xcalloc(num_points+1, 2))  == NULL)||
	 ((seq->traceA   =(TRACE *)xcalloc(num_points+1, 2))  == NULL)||
	 ((seq->traceG   =(TRACE *)xcalloc(num_points+1, 2))  == NULL)||
	 ((seq->traceT   =(TRACE *)xcalloc(num_points+1, 2))  == NULL))
	)
    {
	read_deallocate(seq);
	return NULLRead;
    }
    
    return seq;
}
Пример #10
0
/*
 * ---------------------------------------------------------------------------
 * Loads confidence values from the trace file and averages them.
 * 'opos' is optional - if not known then set to NULL.
 *
 * Returns 0 for success
 *        -1 for failure
 */
int get_read_conf(Exp_info *e, int length, int2 *opos, int1 *conf) {
    int ttype, i;
    FILE *fp;
    uint_1 *prob_A, *prob_C, *prob_G, *prob_T;
    char *seq;
    float scf_version;
    int nbases = 0;

    /* Sanity check */
    if (!(exp_Nentries(e,EFLT_LT) && exp_Nentries(e,EFLT_LN)))
	return -1;

    /* Find and load trace file */
    ttype = trace_type_str2int(exp_get_entry(e, EFLT_LT));

    if (ttype != TT_SCF &&
	ttype != TT_ZTR)
	return -1;

    /*
     * We only support direct reading accuracy values from SCF files.
     * Otherwise we have to take a slower approach.
     */
    if (ttype != TT_SCF) {
	Read *r;
	int sec = read_sections(0);
	read_sections(READ_BASES);

	if (NULL == (r = read_reading(exp_get_entry(e,EFLT_LN), TT_ANYTR))) {
	    read_sections(sec);
	    return -1;
	}

	prob_A = (int1 *)xmalloc(r->NBases);
	prob_C = (int1 *)xmalloc(r->NBases);
	prob_G = (int1 *)xmalloc(r->NBases);
	prob_T = (int1 *)xmalloc(r->NBases);
	seq    = (char *)xmalloc(r->NBases);

	memcpy(prob_A, r->prob_A, r->NBases);
	memcpy(prob_C, r->prob_C, r->NBases);
	memcpy(prob_G, r->prob_G, r->NBases);
	memcpy(prob_T, r->prob_T, r->NBases);
	memcpy(seq,    r->base,   r->NBases);

	nbases = r->NBases;

	read_deallocate(r);
	read_sections(sec);

    } else {
	Header h;
	/* For SCF files we read directly - the above code would also do. */

	if (NULL == (fp = open_trace_file(exp_get_entry(e,EFLT_LN), NULL)))
	    return -1;

	/* Read the SCF header */
	if (-1 == read_scf_header(fp, &h))
	    return -1;
	scf_version = scf_version_str2float(h.version);
	nbases = h.bases;

	/* Alloc memory */
	prob_A = (uint_1 *)xmalloc(h.bases * sizeof(*prob_A));
	prob_C = (uint_1 *)xmalloc(h.bases * sizeof(*prob_A));
	prob_G = (uint_1 *)xmalloc(h.bases * sizeof(*prob_A));
	prob_T = (uint_1 *)xmalloc(h.bases * sizeof(*prob_A));
	seq    = (char   *)xmalloc(h.bases * sizeof(*seq));
	if (NULL == prob_A ||
	    NULL == prob_C ||
	    NULL == prob_G ||
	    NULL == prob_T ||
	    NULL == seq)
	    return -1;

	/* Load base scores */
	if (scf_version >= 3.0) {
	    /*
	     * Version 3 base format:
	     * num_bases * 4byte peak index
	     * num_bases * prob_A
	     * num_bases * prob_C
	     * num_bases * prob_G
	     * num_bases * prob_T
	     * num_bases * base
	     * num_bases * spare (x3)
	     */
	    fseek(fp, (off_t)h.bases_offset + 4 * h.bases, SEEK_SET);
	    if (h.bases != fread(prob_A, 1, h.bases, fp))
		return -1;
	    if (h.bases != fread(prob_C, 1, h.bases, fp))
		return -1;
	    if (h.bases != fread(prob_G, 1, h.bases, fp))
		return -1;
	    if (h.bases != fread(prob_T, 1, h.bases, fp))
		return -1;
	    if (h.bases != fread(seq, 1, h.bases, fp))
		return -1;
	} else {
	    int i;
	    uint_1 buf[12];

	    /*
	     * Version 2 base format
	     * num_bases * base_struct,  where base_struct is 12 bytes:
	     *     0-3 peak_index
	     *     4-7 prob_A/C/G/T
	     *     8   base
	     *     9-  spare
	     */
	    fseek(fp, (off_t)h.bases_offset, SEEK_SET);

	    for (i = 0; (unsigned)i < h.bases; i++) {
		if (1 != fread(buf, 12, 1, fp))
		    return -1;
		prob_A[i] = buf[4];
		prob_C[i] = buf[5];
		prob_G[i] = buf[6];
		prob_T[i] = buf[7];
		seq[i]    = buf[8];
	    }
	}

	fclose(fp);
    }

    /* Determine confidence values */
    if (opos) {
	for (i=0; i<length; i++) {
	    if (opos[i] == 0) {
		/* Inserted base, change to 0% */
		conf[i] = 0;
	    } else {
		switch(seq[opos[i]-1]) {
		case 'a':
		case 'A':
		    conf[i] = prob_A[opos[i]-1];
		    break;
		case 'c':
		case 'C':
		    conf[i] = prob_C[opos[i]-1];
		    break;
		case 'g':
		case 'G':
		    conf[i] = prob_G[opos[i]-1];
		    break;
		case 't':
		case 'T':
		    conf[i] = prob_T[opos[i]-1];
		    break;
		default:
		    conf[i] = 2;
		}
	    }
	}
    } else {
	int mlength = MIN(length, nbases);

	for (i=0; i < mlength; i++) {
	    switch(seq[i]) {
	    case 'a':
	    case 'A':
		conf[i] = prob_A[i];
		break;
	    case 'c':
	    case 'C':
		conf[i] = prob_C[i];
		break;
	    case 'g':
	    case 'G':
		conf[i] = prob_G[i];
		break;
	    case 't':
	    case 'T':
		conf[i] = prob_T[i];
		break;
	    case 'n':
	    case 'N':
	    case '-':
		conf[i] = (prob_A[i] + prob_C[i] + prob_G[i] + prob_T[i]) / 4;
		break;
	    default:
		conf[i] = 2;
	    }
	}
	for (; i < length; i++)
	    conf[i] = 2;
    }

    xfree(prob_A);
    xfree(prob_C);
    xfree(prob_G);
    xfree(prob_T);
    xfree(seq);

    return 0;
}
Пример #11
0
void
elf_mod_symload(int strtablen)
{
	Elf_Ehdr ehdr;
	char *shstrtab;
	struct elf_section *head, *s;
	char *symbuf, *strbuf;

	/*
	 * Seek to the text offset to start loading...
	 */
	if (lseek(modfd, 0, SEEK_SET) == -1)
		err(12, "lseek");
	if (read_elf_header(modfd, &ehdr) < 0)
		return;

	shstrtab = read_shstring_table(modfd, &ehdr);
	read_sections(modfd, &ehdr, shstrtab, &head);

	for (s = head; s; s = s->next) {
		struct elf_section *p = s;

		if ((p->type == SHT_SYMTAB) || (p->type == SHT_DYNSYM)) {
			if (debug)
				fprintf(stderr, "loading `%s': addr = %p, "
				    "size = %#lx\n",
				    s->name, s->addr, (u_long)s->size);
			/*
			 * Seek to the file offset to start loading it...
			 */
			if (lseek(modfd, p->offset, SEEK_SET) == -1)
				err(12, "lseek");
			symbuf = malloc(p->size);
			if (symbuf == 0)
				err(13, "malloc");
			if (read(modfd, symbuf, p->size) != p->size)
				err(14, "read");

			loadsym(symbuf, p->size);
			free(symbuf);
		}
	}

	for (s = head; s; s = s->next) {
		struct elf_section *p = s;

		if ((p->type == SHT_STRTAB) &&
		    (strcmp(p->name, ".strtab") == 0 )) {
			if (debug)
				fprintf(stderr, "loading `%s': addr = %p, "
				    "size = %#lx\n",
				    s->name, s->addr, (u_long)s->size);
			/*
			 * Seek to the file offset to start loading it...
			 */
			if (lseek(modfd, p->offset, SEEK_SET) == -1)
				err(12, "lseek");
			strbuf = malloc(p->size);
			if (strbuf == 0)
				err(13, "malloc");
			if (read(modfd, strbuf, p->size) != p->size)
				err(14, "read");

			loadsym(strbuf, p->size);
			free(strbuf);
		}
	}

	free(shstrtab);
	free_sections(head);
	return;
}
Пример #12
0
/* load a prelinked module; returns entry point */
void *
elf_mod_load(int fd)
{
	Elf_Ehdr ehdr;
	size_t zero_size = 0;
	size_t b;
	ssize_t n;
	char *shstrtab;
	struct elf_section *head, *s;
	char buf[10 * BUFSIZ];
	void *addr = NULL;

	if (read_elf_header(fd, &ehdr) < 0)
		return NULL;

	shstrtab = read_shstring_table(fd, &ehdr);
	read_sections(fd, &ehdr, shstrtab, &head);

	for (s = head; s; s = s->next) {
		if (s->type != SHT_STRTAB && s->type != SHT_SYMTAB &&
		    s->type != SHT_DYNSYM) {
			if (debug)
				fprintf(stderr, "loading `%s': addr = %p, "
				    "size = %#lx\n",
				    s->name, s->addr, (u_long)s->size);
			if (s->type == SHT_NOBITS) {
				/* skip some space */
				zero_size += s->size;
			} else {
				if (addr != NULL) {
					/*
					 * if there is a gap in the prelinked
					 * module, transfer some empty space.
					 */
					zero_size += (char*)s->addr -
					    (char*)addr;
				}
				if (zero_size) {
					loadspace(zero_size);
					zero_size = 0;
				}
				b = s->size;
				if (lseek(fd, s->offset, SEEK_SET) == -1)
					err(1, "lseek");
				while (b) {
					n = read(fd, buf, MIN(b, sizeof(buf)));
					if (n == 0)
						errx(1, "unexpected EOF");
					if (n < 0)
						err(1, "read");
					loadbuf(buf, n);
					b -= n;
				}
				addr = (char*)s->addr + s->size;
			}
		}
	}
	if (zero_size)
		loadspace(zero_size);

	free_sections(head);
	free(shstrtab);
	return (void *)ehdr.e_entry;
}
Пример #13
0
/* return size needed by the module */
int
elf_mod_sizes(int fd, size_t *modsize, int *strtablen,
    struct lmc_resrv *resrvp, struct stat *sp)
{
	Elf_Ehdr ehdr;
	ssize_t off = 0;
	size_t data_hole = 0;
	char *shstrtab, *strtab;
	struct elf_section *head, *s, *stab;

	if (read_elf_header(fd, &ehdr) < 0)
		return -1;
	shstrtab = read_shstring_table(fd, &ehdr);
	read_sections(fd, &ehdr, shstrtab, &head);

	for (s = head; s; s = s->next) {
		/* XXX impossible! */
		if (s->type == SHT_STRTAB && s->type == SHT_SYMTAB &&
		    s->type == SHT_DYNSYM)
			continue;
		if (debug)
			fprintf(stderr,
			    "%s: addr = %p size = %#lx align = %#lx\n",
			    s->name, s->addr, (u_long)s->size, (u_long)s->align);
		/*
		 * XXX try to get rid of the hole before the data
		 * section that GNU-ld likes to put there
		 */
		if (strcmp(s->name, ".data") == 0 && s->addr > (void *)off) {
			data_offset = roundup(off, s->align);
			if (debug)
				fprintf(stderr, ".data section forced to "
				    "offset %p (was %p)\n",
				    (void *)data_offset, s->addr);
			/* later remove size of compressed hole from off */
			data_hole = (ssize_t)s->addr - data_offset;
		}
		off = (ssize_t)s->addr + s->size;
	}
	off -= data_hole;

	/* XXX round to pagesize? */
	*modsize = roundup(off, sysconf(_SC_PAGESIZE));

	/* get string table length */
	strtab = read_string_table(fd, head, strtablen);
	free(shstrtab);
	free(strtab);

	/* get symbol table sections */
	get_symtab(&head);
	stab = head;
	resrvp->sym_symsize = 0;
	while (stab) {
		resrvp->sym_symsize += stab->size;
		stab = stab->next;
	}
	resrvp->sym_size = resrvp->sym_symsize + *strtablen;
	free_sections(head);

	return (0);
}