bool NewChromSweep::next(RecordKeyList &next) {
if (_currQueryRec != NULL) {
_queryFRM->deleteRecord(_currQueryRec);
}
nextRecord(true);
if (_currQueryRec == NULL) { //eof hit!
return false;
}
if (_currDatabaseRec == NULL && _cache.empty() && !_runToQueryEnd) {
return false;
}
_hits.clear();
_currChromName = _currQueryRec->getChrName();
// have we changed chromosomes?
if (!chromChange()) {
// scan the database cache for hits
scanCache();
//skip if we hit the end of the DB
// advance the db until we are ahead of the query. update hits and cache as necessary
while (_currDatabaseRec != NULL &&
_currQueryRec->sameChrom(_currDatabaseRec) &&
!(_currDatabaseRec->after(_currQueryRec))) {
if (intersects(_currQueryRec, _currDatabaseRec)) {
_hits.push_back(_currDatabaseRec);
}
if (_currQueryRec->after(_currDatabaseRec)) {
_databaseFRM->deleteRecord(_currDatabaseRec);
_currDatabaseRec = NULL;
} else {
_cache.push_back(_currDatabaseRec);
_currDatabaseRec = NULL;
}
nextRecord(false);
}
}
next.setKey(_currQueryRec);
next.setListNoCopy(_hits);
return true;
}
void FileRecordMgr::deleteMergedRecord(RecordKeyList &recList)
{
deleteAllMergedItemsButKey(recList);
deleteRecord(recList.getKey());
recList.setKey(NULL);
}
bool FileRecordMgr::allocateAndGetNextMergedRecord(RecordKeyList & recList, WANT_STRAND_TYPE desiredStrand, int maxDistance)
{
if (!recList.allClear()) {
deleteMergedRecord(recList);
}
_mustBeForward = desiredStrand == SAME_STRAND_FORWARD;
_mustBeReverse = desiredStrand == SAME_STRAND_REVERSE;
Record *startRecord = tryToTakeFromStorage();
// if we couldn't use a previously stored record for starters,
//then begin with a new one that matches strand criteria.
while (startRecord == NULL) {
startRecord = allocateAndGetNextRecord();
if (startRecord == NULL) { //hit EOF!!
return false;
}
if (_mustBeForward && !startRecord->getStrand()) {
//record is reverse, wanted forward.
addToStorage(startRecord);
startRecord = NULL;
} else if (_mustBeReverse && startRecord->getStrand()) {
//record is forward, wanted reverse
addToStorage(startRecord);
startRecord = NULL;
}
}
// OK!! We have a start record!
_mustBeForward = desiredStrand == SAME_STRAND_FORWARD || (desiredStrand == SAME_STRAND_EITHER && startRecord->getStrand());
_mustBeReverse = desiredStrand == SAME_STRAND_REVERSE || (desiredStrand == SAME_STRAND_EITHER && !startRecord->getStrand());
const QuickString &currChrom = startRecord->getChrName();
_foundChroms.insert(currChrom);
bool madeComposite = false;
recList.push_back(startRecord);
recList.setKey(startRecord); //key of recList will just be the startRecord unless we're able to merge more.
bool currStrand = startRecord->getStrand();
bool mustMatchStrand = desiredStrand != ANY_STRAND;
int currEnd = startRecord->getEndPos();
//now look for more records to merge with this one.
//stop when they're out of range, not on the same chromosome, or we hit EOF.
//ignore if they don't comply with strand.
Record *nextRecord = NULL;
while (nextRecord == NULL) {
bool takenFromStorage = false;
nextRecord = mustMatchStrand ? tryToTakeFromStorage(currStrand) : tryToTakeFromStorage();
if (nextRecord == NULL) {
nextRecord = allocateAndGetNextRecord();
} else {
takenFromStorage = true;
}
if (nextRecord == NULL) { // EOF hit
break;
}
const QuickString &newChrom = nextRecord->getChrName();
if (newChrom != currChrom) { //hit a different chromosome.
if (_foundChroms.find(newChrom) == _foundChroms.end() || takenFromStorage) {
//haven't seen this chromosome before.
addToStorage(nextRecord);
break;
} else {
//different strand, but we've already seen this chrom. File is not sorted.
fprintf(stderr, "ERROR: Input file %s is not sorted by chromosome, startPos.\n", _context->getInputFileName(_contextFileIdx).c_str());
deleteRecord(nextRecord);
deleteMergedRecord(recList);
exit(1);
}
}
int nextStart = nextRecord->getStartPos();
//is the record out of range?
if (nextStart > currEnd + maxDistance) {
//yes, it's out of range.
addToStorage(nextRecord);
break;
}
//ok, they're on the same chrom and in range. Are we happy with the strand?
if (mustMatchStrand && nextRecord->getStrand() != currStrand) {
//no, we're not.
addToStorage(nextRecord);
nextRecord = NULL;
continue;
}
//everything's good! do a merge.
recList.push_back(nextRecord);
madeComposite = true;
int nextEnd = nextRecord->getEndPos();
if (nextEnd > currEnd) {
currEnd = nextEnd;
}
nextRecord = NULL;
}
if (madeComposite) {
Record *newKey = _recordMgr->allocateRecord();
(*newKey) = (*startRecord);
newKey->setEndPos(currEnd);
recList.setKey(newKey);
}
_totalMergedRecordLength += (unsigned long)(recList.getKey()->getEndPos() - recList.getKey()->getStartPos());
return true;
}