static void seqspecsInitClear (void) {
int i;
if (seqspecs != NULL) {
i = arrayMax (seqspecs);
while (i--)
seqspec_destroy (arru (seqspecs,i,Seqspec));
arrayClear (seqspecs);
}
else
seqspecs = arrayCreate (10,Seqspec);
}
int main(int argc, char *argv[])
{
Array breakPoints;
BreakPoint *currBP;
BreakPointRead *currBPR;
int minNumReads, minNumUniqueOffsets,
minNumReadsForKS,numPossibleOffsets;
double pValueCutoffForKS;
Array offsets;
Array randomNumbers;
double *observedOffsets;
double *randomOffsets;
if (argc != 6) {
usage((char*) "%s <minNumReads> <minNumUniqueOffsets> "
"<minNumReadsForKS> <pValueCutoffForKS> <numPossibleOffsets>",
argv[0]);
}
minNumReads = std::atoi(argv[1]);
minNumUniqueOffsets = std::atoi(argv[2]);
minNumReadsForKS = std::atoi(argv[3]);
pValueCutoffForKS = std::atof(argv[4]);
numPossibleOffsets = std::atoi(argv[5]);
bp_init("-");
offsets = arrayCreate(100, int);
randomNumbers = arrayCreate(100, int);
breakPoints = bp_getBreakPoints();
for (int i = 0; i < arrayMax(breakPoints); i++) {
currBP = arrp(breakPoints, i, BreakPoint);
arrayClear(offsets);
for (int j = 0; j < arrayMax(currBP->breakPointReads); j++) {
currBPR = arrp(currBP->breakPointReads, j, BreakPointRead);
array(offsets, arrayMax(offsets), int) = currBPR->offset;
}
arraySort(offsets, (ARRAYORDERF) arrayIntcmp);
arrayUniq(offsets, NULL, (ARRAYORDERF) arrayIntcmp);
if (arrayMax(currBP->breakPointReads) >= minNumReads &&
arrayMax(currBP->breakPointReads) < minNumReadsForKS) {
if (arrayMax(offsets) >= minNumUniqueOffsets)
std::puts(bp_writeBreakPoint(currBP));
}
else if (arrayMax(currBP->breakPointReads) >= minNumReads &&
arrayMax(currBP->breakPointReads) >= minNumReadsForKS) {
arrayClear(randomNumbers);
for (int j = 0; j < arrayMax(offsets); j++)
array(randomNumbers, arrayMax(randomNumbers), int) = std::rand() % numPossibleOffsets;
arraySort(randomNumbers, (ARRAYORDERF) arrayIntcmp);
observedOffsets = (double *) hlr_malloc(arrayMax(offsets) * sizeof(double));
randomOffsets = (double *) hlr_malloc(arrayMax(offsets) * sizeof(double));
for (int j = 0; j < arrayMax(offsets); j++) {
observedOffsets[j] = arru(offsets, j, int);
randomOffsets[j] = arru(randomNumbers, j, int);
}
if (pValueCutoffForKS < TMath::KolmogorovTest(arrayMax(offsets),
observedOffsets,
arrayMax(offsets),
randomOffsets,
""))
std::puts(bp_writeBreakPoint(currBP));
hlr_free(observedOffsets);
hlr_free(randomOffsets);
}
}
