示例#1
0
static void updateMembers(Node * bypass, Node * nextNode)
{
	PassageMarkerI marker, next, tmp;
	Coordinate nextLength = getNodeLength(nextNode);

	// Update  marker + arc info
	for (marker = getMarker(bypass); marker != NULL_IDX; marker = tmp) {
		tmp = getNextInNode(marker);

		if (!isTerminal(marker)
		    && getNode(getNextInSequence(marker)) == nextNode) {
			// Marker steps right into target
			next = getNextInSequence(marker);
			disconnectNextPassageMarker(marker, graph);
			destroyPassageMarker(next);
		} else if (getUniqueness(nextNode)
			   && goesToNode(marker, nextNode)) {
			// Marker goes indirectly to target
			while (getNode(getNextInSequence(marker)) !=
			       nextNode) {
				next = getNextInSequence(marker);
				disconnectNextPassageMarker(marker, graph);
				destroyPassageMarker(next);
			}

			next = getNextInSequence(marker);
			disconnectNextPassageMarker(marker, graph);
			destroyPassageMarker(next);
		} else if (!isTerminal(marker)
			   && getFinishOffset(marker) == 0) {
			// Marker goes somewhere else than to target
			next = getNextInSequence(marker);
			incrementFinishOffset(marker, nextLength);
		} else {
			// Marker goes nowhere
			incrementFinishOffset(marker, nextLength);
		}
	}
}
示例#2
0
// Replaces two consecutive nodes into a single equivalent node
// The extra memory is freed
void concatenateNodes(Node * nodeA, Node * nodeB, Graph * graph)
{
	PassageMarkerI marker, tmpMarker;
	Node *twinA = getTwinNode(nodeA);
	Node *twinB = getTwinNode(nodeB);
	Arc *arc;
	Category cat;

	// Arc management:
	// Freeing useless arcs
	while (getArc(nodeA) != NULL)
		destroyArc(getArc(nodeA), graph);

	// Correct arcs
	for (arc = getArc(nodeB); arc != NULL; arc = getNextArc(arc)) {
		if (getDestination(arc) != twinB)
			createAnalogousArc(nodeA, getDestination(arc),
					   arc, graph);
		else
			createAnalogousArc(nodeA, twinA, arc, graph);
	}

	// Passage marker management in node A:
	for (marker = getMarker(nodeA); marker != NULL_IDX;
	     marker = getNextInNode(marker))
		if (isTerminal(marker))
			incrementFinishOffset(marker,
					      getNodeLength(nodeB));

	// Swapping new born passageMarkers from B to A
	for (marker = getMarker(nodeB); marker != NULL_IDX; marker = tmpMarker) {
		tmpMarker = getNextInNode(marker);

		if (isInitial(marker)
		    || getNode(getPreviousInSequence(marker)) != nodeA) {
			extractPassageMarker(marker);
			transposePassageMarker(marker, nodeA);
			incrementFinishOffset(getTwinMarker(marker),
					      getNodeLength(nodeA));
		} else
			disconnectNextPassageMarker(getPreviousInSequence
						    (marker), graph);
	}

	// Read starts
	concatenateReadStarts(nodeA, nodeB, graph);

	// Gaps
	appendNodeGaps(nodeA, nodeB, graph);

	// Descriptor management (node)
	appendDescriptors(nodeA, nodeB);

	// Update uniqueness:
	setUniqueness(nodeA, getUniqueness(nodeA) || getUniqueness(nodeB));

	// Update virtual coverage
	for (cat = 0; cat < CATEGORIES; cat++)
		incrementVirtualCoverage(nodeA, cat,
					 getVirtualCoverage(nodeB, cat));

	// Update original virtual coverage
	for (cat = 0; cat < CATEGORIES; cat++)
		incrementOriginalVirtualCoverage(nodeA, cat,
						 getOriginalVirtualCoverage
						 (nodeB, cat));

	// Freeing gobbled node
	destroyNode(nodeB, graph);
}
示例#3
0
// Replaces two consecutive nodes into a single equivalent node
// The extra memory is freed
void concatenateStringOfNodes(Node * nodeA, Graph * graph)
{
	Node *twinA = getTwinNode(nodeA);
	Node * nodeB = nodeA;
	Node * twinB;
	Node *currentNode, *nextNode;
	Coordinate totalLength = 0;
	PassageMarkerI marker, tmpMarker;
	Arc *arc;
	Category cat;

	while (simpleArcCount(nodeB) == 1
	       &&
	       simpleArcCount(getTwinNode
			      (getDestination(getArc(nodeB)))) ==
	       1
	       && getDestination(getArc(nodeB)) != getTwinNode(nodeB)
	       && getDestination(getArc(nodeB)) != nodeA) {
		totalLength += getNodeLength(nodeB);
		nodeB = getDestination(getArc(nodeB));
	}
	twinB = getTwinNode(nodeB);
	totalLength += getNodeLength(nodeB);
	reallocateNodeDescriptor(nodeA, totalLength);

	currentNode = nodeA;
	while (currentNode != nodeB) {		
		currentNode = getDestination(getArc(currentNode));

		// Passage marker management in node A:
		for (marker = getMarker(nodeA); marker != NULL_IDX;
		     marker = getNextInNode(marker))
			if (getNode(getNextInSequence(marker)) != currentNode)
				incrementFinishOffset(marker,
						      getNodeLength(currentNode));

		// Swapping new born passageMarkers from B to A
		for (marker = getMarker(currentNode); marker != NULL_IDX; marker = tmpMarker) {
			tmpMarker = getNextInNode(marker);

			if (isInitial(marker)
			    || getNode(getPreviousInSequence(marker)) != nodeA) {
				extractPassageMarker(marker);
				transposePassageMarker(marker, nodeA);
				incrementFinishOffset(getTwinMarker(marker),
						      getNodeLength(nodeA));
			} else
				disconnectNextPassageMarker(getPreviousInSequence
							    (marker), graph);
		}

		// Read starts
		concatenateReadStarts(nodeA, currentNode, graph);

		// Gaps
		appendNodeGaps(nodeA, currentNode, graph);

		// Update uniqueness:
		setUniqueness(nodeA, getUniqueness(nodeA) || getUniqueness(currentNode));

		// Update virtual coverage
		for (cat = 0; cat < CATEGORIES; cat++)
			incrementVirtualCoverage(nodeA, cat,
						 getVirtualCoverage(currentNode, cat));

		// Update original virtual coverage
		for (cat = 0; cat < CATEGORIES; cat++)
			incrementOriginalVirtualCoverage(nodeA, cat,
							 getOriginalVirtualCoverage
							 (currentNode, cat));
		// Descriptor management (node)
		directlyAppendDescriptors(nodeA, currentNode, totalLength);
	}

	// Correct arcs
	for (arc = getArc(nodeB); arc != NULL; arc = getNextArc(arc)) {
		if (getDestination(arc) != twinB)
			createAnalogousArc(nodeA, getDestination(arc),
					   arc, graph);
		else
			createAnalogousArc(nodeA, twinA, arc, graph);
	}

	// Freeing gobbled nodes
	currentNode = getTwinNode(nodeB);
	while (currentNode != getTwinNode(nodeA)) {
		arc = getArc(currentNode);
		nextNode = getDestination(arc);
		destroyNode(currentNode, graph);
		currentNode = nextNode;
	}
}
示例#4
0
static Node *bypass()
{
	Node *bypass = getNode(path);
	Node *next = NULL;
	Arc *arc;
	PassageMarkerI nextMarker;

	// Remove unwanted arcs
	while (getArc(bypass) != NULL)
		destroyArc(getArc(bypass), graph);

	// Update extensive variables (length + descriptors + passage markers)
	while (!isTerminal(path)) {
		nextMarker = getNextInSequence(path);
		next = getNode(nextMarker);
		while (next == bypass) {
			disconnectNextPassageMarker(path, graph);
			destroyPassageMarker(nextMarker);
			nextMarker = getNextInSequence(path);
			next = getNode(nextMarker);
		}

		if (next == NULL)
			return bypass;

		// Overall node update 
		if (!getUniqueness(next)) {
			adjustShortReads(bypass, getNextInSequence(path));
			appendSequence(bypass, sequences,
				       getNextInSequence(path), graph);
		} else {
			concatenateReadStarts(bypass, next, graph);

#ifndef SINGLE_COV_CAT
			Category cat;
			for (cat = 0; cat < CATEGORIES; cat++) {
				// Update virtual coverage
				incrementVirtualCoverage(bypass, cat,
							 getVirtualCoverage(next, cat));
				// Update original virtual coverage
				incrementOriginalVirtualCoverage(bypass, cat,
								 getOriginalVirtualCoverage(next, cat));
			}
#else
			incrementVirtualCoverage(bypass, getVirtualCoverage(next));
#endif
			appendDescriptors(bypass, next);
		}

		// Members
		updateMembers(bypass, next);

		// Termination 
		if (isTerminal(path) || getUniqueness(next))
			break;
	}

	// Remove unique groupies from arrival 
	admitGroupies(next, bypass);

	// Copy destination arcs
	for (arc = getArc(next); arc != NULL; arc = getNextArc(arc)) {
		if (getDestination(arc) == next)
			continue;
		else if (getDestination(arc) == getTwinNode(next))
			createAnalogousArc(bypass, getTwinNode(bypass),
					   arc, graph);
		else
			createAnalogousArc(bypass, getDestination(arc),
					   arc, graph);
	}

	destroyNode(next, graph);

	return bypass;
}