Esempio n. 1
0
void ApoptoticCellKiller<SPACE_DIM>::CheckAndLabelSingleCellForApoptosis(CellPtr pCell)
{
    if (pCell->HasCellProperty<ApoptoticCellProperty>() && !(pCell->HasApoptosisBegun()))
    {
        pCell->StartApoptosis();
    }
}
Esempio n. 2
0
void RandomCellKiller<DIM>::CheckAndLabelSingleCellForApoptosis(CellPtr pCell)
{
    /*
     * We assume a constant time step and that there are an integer number (n = 1/dt)
     * of time steps per hour. We also assume that this method is called every time step
     * and that the probabilities of dying at different times are independent.
     *
     * Let q=mProbabilityOfDeathInAnHour and p="probability of death in a given time step".
     *
     * Probability of not dying in an hour:
     * (1-q) = (1-p)^n = (1-p)^(1/dt).
     *
     * Rearranging for p:
     * p = 1 - (1-q)^dt.
     */
    double death_prob_this_timestep = 1.0 - pow((1.0 - mProbabilityOfDeathInAnHour), SimulationTime::Instance()->GetTimeStep());

    if (!pCell->HasApoptosisBegun() &&
        RandomNumberGenerator::Instance()->ranf() < death_prob_this_timestep)
    {
        pCell->StartApoptosis();
    }
}